epitiostanol-4204 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the epitiostanol-4204 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHNAK AHNAK nucleoprotein
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APC adenomatous polyposis coli
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATG10 autophagy related 10
BAGE B melanoma antigen
C11ORF63 chromosome 11 open reading frame 63
CA5B carbonic anhydrase VB, mitochondrial
CCDC121 coiled-coil domain containing 121
CTC1 CTS telomere maintenance complex component 1
CTNS cystinosin, lysosomal cystine transporter
CTSK cathepsin K
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DOC2A double C2-like domains, alpha
DOK4 docking protein 4
ERAP1 endoplasmic reticulum aminopeptidase 1
ERCC5 excision repair cross-complementation group 5
FBXL8 F-box and leucine-rich repeat protein 8
FGB fibrinogen beta chain
FLT1 fms-related tyrosine kinase 1
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FRZB frizzled-related protein
GAS7 growth arrest-specific 7
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GK3P glycerol kinase 3 pseudogene
GPR15 G protein-coupled receptor 15
HDAC6 histone deacetylase 6
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HFE hemochromatosis
HIST1H2AL histone cluster 1, H2al
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DOA major histocompatibility complex, class II, DO alpha
HOXC5 homeobox C5
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IGLL1 immunoglobulin lambda-like polypeptide 1
IL18R1 interleukin 18 receptor 1
IRS4 insulin receptor substrate 4
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KMT2A lysine (K)-specific methyltransferase 2A
KRT10 keratin 10, type I
LARGE like-glycosyltransferase
LINC00216 long intergenic non-protein coding RNA 216
LOX lysyl oxidase
MCF2L MCF.2 cell line derived transforming sequence-like
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MSTN myostatin
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
MYL10 myosin, light chain 10, regulatory
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OR10H1 olfactory receptor, family 10, subfamily H, member 1
OSBPL10 oxysterol binding protein-like 10
PALMD palmdelphin
PCDHA5 protocadherin alpha 5
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDLIM5 PDZ and LIM domain 5
PPARD peroxisome proliferator-activated receptor delta
PRB4 proline-rich protein BstNI subfamily 4
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PTH2R parathyroid hormone 2 receptor
PTHLH parathyroid hormone-like hormone
PTPRJ protein tyrosine phosphatase, receptor type, J
RAB36 RAB36, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RET ret proto-oncogene
RNASE4 ribonuclease, RNase A family, 4
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
RXRB retinoid X receptor, beta
SCARB1 scavenger receptor class B, member 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SEZ6L seizure related 6 homolog (mouse)-like
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC22A14 solute carrier family 22, member 14
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMAD4 SMAD family member 4
SOS2 son of sevenless homolog 2 (Drosophila)
SRSF1 serine/arginine-rich splicing factor 1
SSTR4 somatostatin receptor 4
STAT1 signal transducer and activator of transcription 1, 91kDa
STON1 stonin 1
SULF1 sulfatase 1
SULT4A1 sulfotransferase family 4A, member 1
TRIM29 tripartite motif containing 29
TRPM1 transient receptor potential cation channel, subfamily M, member 1
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
WFDC2 WAP four-disulfide core domain 2
ZBTB20 zinc finger and BTB domain containing 20
ZNF492 zinc finger protein 492
ZNF695 zinc finger protein 695

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ALPK1 alpha-kinase 1
AMBRA1 autophagy/beclin-1 regulator 1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARHGAP22 Rho GTPase activating protein 22
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
AXIN1 axin 1
C22ORF46 chromosome 22 open reading frame 46
C5ORF45 chromosome 5 open reading frame 45
C8A complement component 8, alpha polypeptide
CAPN15 calpain 15
CASP5 caspase 5, apoptosis-related cysteine peptidase
CBX8 chromobox homolog 8
CCDC85C coiled-coil domain containing 85C
CCNJL cyclin J-like
CD70 CD70 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEMP1 cementum protein 1
CLTCL1 clathrin, heavy chain-like 1
CNN1 calponin 1, basic, smooth muscle
CORO1A coronin, actin binding protein, 1A
CORT cortistatin
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CXCL3 chemokine (C-X-C motif) ligand 3
DSPP dentin sialophosphoprotein
EBF2 early B-cell factor 2
ELP6 elongator acetyltransferase complex subunit 6
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXO2 F-box protein 2
FGF23 fibroblast growth factor 23
FLJ21369 uncharacterized protein FLJ21369
FRMPD1 FERM and PDZ domain containing 1
FSD1 fibronectin type III and SPRY domain containing 1
GIF gastric intrinsic factor (vitamin B synthesis)
HIST1H2BN histone cluster 1, H2bn
HOXA6 homeobox A6
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL6 interleukin 6
ITGB7 integrin, beta 7
KANSL3 KAT8 regulatory NSL complex subunit 3
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA1456 KIAA1456
KRT20 keratin 20, type I
KRT86 keratin 86, type II
KRT8P12 keratin 8 pseudogene 12
LIME1 Lck interacting transmembrane adaptor 1
LOC100127972 uncharacterized LOC100127972
LOC157562 uncharacterized LOC157562
LRRK1 leucine-rich repeat kinase 1
LY6D lymphocyte antigen 6 complex, locus D
MAST3 microtubule associated serine/threonine kinase 3
MB myoglobin
MFGE8 milk fat globule-EGF factor 8 protein
MFSD10 major facilitator superfamily domain containing 10
MGP matrix Gla protein
MRAS muscle RAS oncogene homolog
MRPL41 mitochondrial ribosomal protein L41
MTSS1L metastasis suppressor 1-like
MYO1F myosin IF
MYOZ3 myozenin 3
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAT6 N-acetyltransferase 6 (GCN5-related)
NBEAL2 neurobeachin-like 2
NSUN6 NOP2/Sun domain family, member 6
NT5M 5',3'-nucleotidase, mitochondrial
ONECUT2 one cut homeobox 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PAX9 paired box 9
PLD3 phospholipase D family, member 3
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRB3 proline-rich protein BstNI subfamily 3
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB3A RAB3A, member RAS oncogene family
RAP1GAP2 RAP1 GTPase activating protein 2
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF2 ring finger protein 2
SCARA3 scavenger receptor class A, member 3
SOX21 SRY (sex determining region Y)-box 21
SPATA1 spermatogenesis associated 1
SSBP3 single stranded DNA binding protein 3
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TESPA1 thymocyte expressed, positive selection associated 1
TLN1 talin 1
TMPRSS4 transmembrane protease, serine 4
TRAF2 TNF receptor-associated factor 2
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3C tubulin, alpha 3c
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VGLL3 vestigial-like family member 3
XAB2 XPA binding protein 2
ZC3H3 zinc finger CCCH-type containing 3
ZNF222 zinc finger protein 222
ZNF408 zinc finger protein 408
ZNF749 zinc finger protein 749
ZNF862 zinc finger protein 862