epitiostanol-4788 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the epitiostanol-4788 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ACSL4 acyl-CoA synthetase long-chain family member 4
ADAM10 ADAM metallopeptidase domain 10
AMPD1 adenosine monophosphate deaminase 1
AMPD3 adenosine monophosphate deaminase 3
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
APOM apolipoprotein M
B3GAT1 beta-1,3-glucuronyltransferase 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BDKRB2 bradykinin receptor B2
BGLAP bone gamma-carboxyglutamate (gla) protein
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C1ORF54 chromosome 1 open reading frame 54
C8ORF44 chromosome 8 open reading frame 44
CD200 CD200 molecule
CD58 CD58 molecule
CES3 carboxylesterase 3
CHST10 carbohydrate sulfotransferase 10
CLDN1 claudin 1
CLDND1 claudin domain containing 1
COL1A1 collagen, type I, alpha 1
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EGR3 early growth response 3
EMID1 EMI domain containing 1
EPHA1 EPH receptor A1
EPOR erythropoietin receptor
EXOC7 exocyst complex component 7
FGF13 fibroblast growth factor 13
FH fumarate hydratase
FSCN3 fascin actin-bundling protein 3, testicular
GLDC glycine dehydrogenase (decarboxylating)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GRB10 growth factor receptor-bound protein 10
GSTP1 glutathione S-transferase pi 1
HBS1L HBS1-like translational GTPase
HMGA1 high mobility group AT-hook 1
HOXA4 homeobox A4
HOXC5 homeobox C5
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
JAK2 Janus kinase 2
KANK1 KN motif and ankyrin repeat domains 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDM4B lysine (K)-specific demethylase 4B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYCNOS MYCN opposite strand
NAT6 N-acetyltransferase 6 (GCN5-related)
NAV2 neuron navigator 2
NFX1 nuclear transcription factor, X-box binding 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
NUMA1 nuclear mitotic apparatus protein 1
OLFML2A olfactomedin-like 2A
PAPPA2 pappalysin 2
PCNXL2 pecanex-like 2 (Drosophila)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTBP3 polypyrimidine tract binding protein 3
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAD51 RAD51 recombinase
RAI2 retinoic acid induced 2
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
REPS1 RALBP1 associated Eps domain containing 1
RND1 Rho family GTPase 1
SAA4 serum amyloid A4, constitutive
SCAND2P SCAN domain containing 2 pseudogene
SEC23A Sec23 homolog A (S. cerevisiae)
SGCE sarcoglycan, epsilon
SH3GL3 SH3-domain GRB2-like 3
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SMAD5 SMAD family member 5
SPEG SPEG complex locus
SQLE squalene epoxidase
STX7 syntaxin 7
SWAP70 SWAP switching B-cell complex 70kDa subunit
TBX2 T-box 2
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGFBR3 transforming growth factor, beta receptor III
TGM2 transglutaminase 2
THBS3 thrombospondin 3
TMEM209 transmembrane protein 209
TRIM2 tripartite motif containing 2
TRIM68 tripartite motif containing 68
TSPAN9 tetraspanin 9
UPK3B uroplakin 3B
VARS valyl-tRNA synthetase
ZNF532 zinc finger protein 532

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD3A ATPase family, AAA domain containing 3A
ATG14 autophagy related 14
CAPN5 calpain 5
CD79B CD79b molecule, immunoglobulin-associated beta
CDADC1 cytidine and dCMP deaminase domain containing 1
CLDN4 claudin 4
CRIP1 cysteine-rich protein 1 (intestinal)
CUL9 cullin 9
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DENND4C DENN/MADD domain containing 4C
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA4 EPH receptor A4
FAM186A family with sequence similarity 186, member A
FLJ22184
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GEMIN8 gem (nuclear organelle) associated protein 8
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPATCH2 G patch domain containing 2
GRB7 growth factor receptor-bound protein 7
GRWD1 glutamate-rich WD repeat containing 1
GSTA4 glutathione S-transferase alpha 4
GSTT1 glutathione S-transferase theta 1
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H2BJ histone cluster 1, H2bj
HIST1H4D histone cluster 1, H4d
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFT140 intraflagellar transport 140
IFT22 intraflagellar transport 22
IL17RA interleukin 17 receptor A
IL4R interleukin 4 receptor
IQSEC2 IQ motif and Sec7 domain 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
JUNB jun B proto-oncogene
KAT2A K(lysine) acetyltransferase 2A
KIF13B kinesin family member 13B
KRT31 keratin 31, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LZTR1 leucine-zipper-like transcription regulator 1
MAP1S microtubule-associated protein 1S
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRPS18C mitochondrial ribosomal protein S18C
MUC3B mucin 3B, cell surface associated
MYO1F myosin IF
NACA2 nascent polypeptide-associated complex alpha subunit 2
NLRX1 NLR family member X1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PEX26 peroxisomal biogenesis factor 26
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PP14571 uncharacterized LOC100130449
PTCD2 pentatricopeptide repeat domain 2
RAD54L2 RAD54-like 2 (S. cerevisiae)
RCAN3 RCAN family member 3
SAMD9 sterile alpha motif domain containing 9
SCAI suppressor of cancer cell invasion
SCHIP1 schwannomin interacting protein 1
SDC3 syndecan 3
SKIL SKI-like proto-oncogene
SLC4A2 solute carrier family 4 (anion exchanger), member 2
STEAP4 STEAP family member 4
SUN2 Sad1 and UNC84 domain containing 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
THAP7 THAP domain containing 7
TICAM1 toll-like receptor adaptor molecule 1
TIGD6 tigger transposable element derived 6
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM121 transmembrane protein 121
TMEM62 transmembrane protein 62
TNS2 tensin 2
TPK1 thiamin pyrophosphokinase 1
TPRA1 transmembrane protein, adipocyte asscociated 1
TRIM25 tripartite motif containing 25
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSGA10 testis specific, 10
TSPAN1 tetraspanin 1
UBQLN4 ubiquilin 4
UPP1 uridine phosphorylase 1
USP27X ubiquitin specific peptidase 27, X-linked
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
XAB2 XPA binding protein 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB48 zinc finger and BTB domain containing 48
ZFP69B ZFP69 zinc finger protein B
ZNF205 zinc finger protein 205
ZNF324 zinc finger protein 324
ZNF652 zinc finger protein 652
ZNF767P zinc finger family member 767, pseudogene
ZNF768 zinc finger protein 768
ZNF804A zinc finger protein 804A