epitiostanol-7342 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the epitiostanol-7342 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALS2CL ALS2 C-terminal like
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
AREG amphiregulin
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARNT aryl hydrocarbon receptor nuclear translocator
ARTN artemin
BAIAP3 BAI1-associated protein 3
BCL6 B-cell CLL/lymphoma 6
CADM3 cell adhesion molecule 3
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD79A CD79a molecule, immunoglobulin-associated alpha
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
COL11A2 collagen, type XI, alpha 2
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
DIEXF digestive organ expansion factor homolog (zebrafish)
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
E2F4 E2F transcription factor 4, p107/p130-binding
EGR3 early growth response 3
ELOVL5 ELOVL fatty acid elongase 5
EPHA1 EPH receptor A1
EPOR erythropoietin receptor
EVA1B eva-1 homolog B (C. elegans)
FAM169A family with sequence similarity 169, member A
FAM46C family with sequence similarity 46, member C
FAM50B family with sequence similarity 50, member B
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGFR4 fibroblast growth factor receptor 4
FLRT3 fibronectin leucine rich transmembrane protein 3
FSCN1 fascin actin-bundling protein 1
FZD7 frizzled class receptor 7
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GLP1R glucagon-like peptide 1 receptor
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GOLGA2 golgin A2
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HFE hemochromatosis
HPS1 Hermansky-Pudlak syndrome 1
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
INSIG1 insulin induced gene 1
IQCG IQ motif containing G
IRS2 insulin receptor substrate 2
JADE2 jade family PHD finger 2
JAK2 Janus kinase 2
JAM3 junctional adhesion molecule 3
KDM4B lysine (K)-specific demethylase 4B
LACTB2 lactamase, beta 2
LHX6 LIM homeobox 6
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LZTFL1 leucine zipper transcription factor-like 1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MARS methionyl-tRNA synthetase
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NME5 NME/NM23 family member 5
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPY1R neuropeptide Y receptor Y1
PADI2 peptidyl arginine deiminase, type II
PAPOLA poly(A) polymerase alpha
PDAP1 PDGFA associated protein 1
PER3 period circadian clock 3
PGR progesterone receptor
PLA2G3 phospholipase A2, group III
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRODH proline dehydrogenase (oxidase) 1
PXDC1 PX domain containing 1
RAD52 RAD52 homolog (S. cerevisiae)
RBM34 RNA binding motif protein 34
RECQL5 RecQ protein-like 5
RSU1 Ras suppressor protein 1
RUNDC3A RUN domain containing 3A
RUNX1 runt-related transcription factor 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SGK1 serum/glucocorticoid regulated kinase 1
SH3BP2 SH3-domain binding protein 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMOX spermine oxidase
SOX3 SRY (sex determining region Y)-box 3
SREBF2 sterol regulatory element binding transcription factor 2
SSPN sarcospan
STK17B serine/threonine kinase 17b
SYBU syntabulin (syntaxin-interacting)
TLE4 transducin-like enhancer of split 4
TLN2 talin 2
TMPRSS3 transmembrane protease, serine 3
TRIB2 tribbles pseudokinase 2
TRIM32 tripartite motif containing 32
TRIP11 thyroid hormone receptor interactor 11
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
ZNF235 zinc finger protein 235
ZNF37BP zinc finger protein 37B, pseudogene
ZNF516 zinc finger protein 516
ZNF821 zinc finger protein 821
ZNRD1-AS1 ZNRD1 antisense RNA 1

decreased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABHD17B abhydrolase domain containing 17B
AGO1 argonaute RISC catalytic component 1
AHDC1 AT hook, DNA binding motif, containing 1
AIM1 absent in melanoma 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKRD26 ankyrin repeat domain 26
APOD apolipoprotein D
BACE1 beta-site APP-cleaving enzyme 1
BMP4 bone morphogenetic protein 4
CAPN15 calpain 15
CAPN5 calpain 5
CARD8 caspase recruitment domain family, member 8
CBX7 chromobox homolog 7
CENPT centromere protein T
CEP85 centrosomal protein 85kDa
CIR1 corepressor interacting with RBPJ, 1
CLDN9 claudin 9
CLSPN claspin
CRBN cereblon
CTAGE9 CTAGE family, member 9
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNALI1 dynein, axonemal, light intermediate chain 1
EFNA1 ephrin-A1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENO2 enolase 2 (gamma, neuronal)
EPHA2 EPH receptor A2
ESRP2 epithelial splicing regulatory protein 2
F8 coagulation factor VIII, procoagulant component
FAM53B family with sequence similarity 53, member B
FAM63A family with sequence similarity 63, member A
FANCE Fanconi anemia, complementation group E
FLT4 fms-related tyrosine kinase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GSTT1 glutathione S-transferase theta 1
HIST1H2BC histone cluster 1, H2bc
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXC10 homeobox C10
HOXC13 homeobox C13
IFI6 interferon, alpha-inducible protein 6
INCENP inner centromere protein antigens 135/155kDa
IRF6 interferon regulatory factor 6
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL25 kelch-like family member 25
KREMEN2 kringle containing transmembrane protein 2
LINC00339 long intergenic non-protein coding RNA 339
LMO2 LIM domain only 2 (rhombotin-like 1)
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LZTR1 leucine-zipper-like transcription regulator 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
NEK11 NIMA-related kinase 11
NPIPB15 nuclear pore complex interacting protein family, member B15
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PACS1 phosphofurin acidic cluster sorting protein 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
RANGRF RAN guanine nucleotide release factor
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF25 ring finger protein 25
RNF31 ring finger protein 31
RPGR retinitis pigmentosa GTPase regulator
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPUSD2 RNA pseudouridylate synthase domain containing 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETD8 SET domain containing (lysine methyltransferase) 8
SKIL SKI-like proto-oncogene
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC46A3 solute carrier family 46, member 3
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STX1A syntaxin 1A (brain)
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SYTL2 synaptotagmin-like 2
TAOK1 TAO kinase 1
TARP TCR gamma alternate reading frame protein
TCTN2 tectonic family member 2
TRIM5 tripartite motif containing 5
TTLL1 tubulin tyrosine ligase-like family member 1
TYK2 tyrosine kinase 2
UBE2L6 ubiquitin-conjugating enzyme E2L 6
VAX2 ventral anterior homeobox 2
VEGFC vascular endothelial growth factor C
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR62 WD repeat domain 62
XYLT2 xylosyltransferase II
ZNF510 zinc finger protein 510
ZNF665 zinc finger protein 665
ZNF675 zinc finger protein 675