epivincamine-4500 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the epivincamine-4500 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AMIGO2 adhesion molecule with Ig-like domain 2
ANGPTL2 angiopoietin-like 2
ANGPTL4 angiopoietin-like 4
APAF1 apoptotic peptidase activating factor 1
APOE apolipoprotein E
ARSD arylsulfatase D
ASIC4 acid sensing (proton gated) ion channel family member 4
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
BMP6 bone morphogenetic protein 6
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
CABP1 calcium binding protein 1
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD22 CD22 molecule
CD68 CD68 molecule
CDK13 cyclin-dependent kinase 13
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEP41 centrosomal protein 41kDa
COL7A1 collagen, type VII, alpha 1
CSF1 colony stimulating factor 1 (macrophage)
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYR61 cysteine-rich, angiogenic inducer, 61
DSTYK dual serine/threonine and tyrosine protein kinase
ELAC2 elaC ribonuclease Z 2
ESRRG estrogen-related receptor gamma
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FKRP fukutin related protein
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GADD45B growth arrest and DNA-damage-inducible, beta
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPATCH4 G patch domain containing 4
GPRC5B G protein-coupled receptor, class C, group 5, member B
HCG9 HLA complex group 9 (non-protein coding)
HCRP1 hepatocellular carcinoma-related HCRP1
HOMER3 homer scaffolding protein 3
IL6ST interleukin 6 signal transducer
IMPG2 interphotoreceptor matrix proteoglycan 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KANSL3 KAT8 regulatory NSL complex subunit 3
KCTD14 potassium channel tetramerization domain containing 14
KIAA0319L KIAA0319-like
KRT4 keratin 4, type II
LATS1 large tumor suppressor kinase 1
LEFTY1 left-right determination factor 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MRPL41 mitochondrial ribosomal protein L41
MYH14 myosin, heavy chain 14, non-muscle
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PDE4DIP phosphodiesterase 4D interacting protein
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POM121L2 POM121 transmembrane nucleoporin-like 2
PRLH prolactin releasing hormone
PTGDR2 prostaglandin D2 receptor 2
PTPRU protein tyrosine phosphatase, receptor type, U
PVR poliovirus receptor
QPCTL glutaminyl-peptide cyclotransferase-like
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RGS7 regulator of G-protein signaling 7
RND1 Rho family GTPase 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPL35A ribosomal protein L35a
SEC14L4 SEC14-like 4 (S. cerevisiae)
SIRPB1 signal-regulatory protein beta 1
SIT1 signaling threshold regulating transmembrane adaptor 1
SKIL SKI-like proto-oncogene
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SPN sialophorin
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRRT serrate, RNA effector molecule
SULT4A1 sulfotransferase family 4A, member 1
SYT13 synaptotagmin XIII
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGFB2 transforming growth factor, beta 2
TMPRSS15 transmembrane protease, serine 15
TNN tenascin N
TREM1 triggering receptor expressed on myeloid cells 1
UGCG UDP-glucose ceramide glucosyltransferase
USP22 ubiquitin specific peptidase 22
VGLL1 vestigial-like family member 1
WDR62 WD repeat domain 62
WTAP Wilms tumor 1 associated protein
ZCCHC11 zinc finger, CCHC domain containing 11
ZHX3 zinc fingers and homeoboxes 3
ZNF225 zinc finger protein 225
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C14ORF93 chromosome 14 open reading frame 93
CBX7 chromobox homolog 7
CCNO cyclin O
CD70 CD70 molecule
CDHR2 cadherin-related family member 2
CDKL3 cyclin-dependent kinase-like 3
CEP295 centrosomal protein 295kDa
CIDEC cell death-inducing DFFA-like effector c
CLN3 ceroid-lipofuscinosis, neuronal 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRY2 cryptochrome circadian clock 2
CTC1 CTS telomere maintenance complex component 1
CTSK cathepsin K
DTX2 deltex 2, E3 ubiquitin ligase
ERN2 endoplasmic reticulum to nucleus signaling 2
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM204A family with sequence similarity 204, member A
FAM50B family with sequence similarity 50, member B
FBXO2 F-box protein 2
FKBP10 FK506 binding protein 10, 65 kDa
GAL3ST4 galactose-3-O-sulfotransferase 4
GAREM GRB2 associated, regulator of MAPK1
GEMIN8 gem (nuclear organelle) associated protein 8
GLS2 glutaminase 2 (liver, mitochondrial)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRAMD1B GRAM domain containing 1B
GRAMD1C GRAM domain containing 1C
GRB7 growth factor receptor-bound protein 7
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
H1F0 H1 histone family, member 0
HDAC7 histone deacetylase 7
HHLA3 HERV-H LTR-associating 3
HIST1H4D histone cluster 1, H4d
HIST1H4E histone cluster 1, H4e
HIST2H2AA3 histone cluster 2, H2aa3
HMHA1 histocompatibility (minor) HA-1
IL33 interleukin 33
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0754 KIAA0754
LIPG lipase, endothelial
LMNB1 lamin B1
LOC257152 uncharacterized LOC257152
LPAR3 lysophosphatidic acid receptor 3
METTL16 methyltransferase like 16
MX1 MX dynamin-like GTPase 1
MXRA8 matrix-remodelling associated 8
MYO1D myosin ID
MYO1F myosin IF
NAT6 N-acetyltransferase 6 (GCN5-related)
NBEAL2 neurobeachin-like 2
NECAP2 NECAP endocytosis associated 2
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCDHA9 protocadherin alpha 9
PCOLCE procollagen C-endopeptidase enhancer
PDE8B phosphodiesterase 8B
PER3 period circadian clock 3
PLD2 phospholipase D2
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLL polymerase (DNA directed), lambda
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RAB3A RAB3A, member RAS oncogene family
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RGS17 regulator of G-protein signaling 17
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SGK2 serum/glucocorticoid regulated kinase 2
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMR3A submaxillary gland androgen regulated protein 3A
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STARD3 StAR-related lipid transfer (START) domain containing 3
STON1 stonin 1
STRN striatin, calmodulin binding protein
SYT17 synaptotagmin XVII
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAGLN3 transgelin 3
TGFB3 transforming growth factor, beta 3
TH tyrosine hydroxylase
TMEM8B transmembrane protein 8B
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VEGFB vascular endothelial growth factor B
WDR91 WD repeat domain 91
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZBTB22 zinc finger and BTB domain containing 22
ZC3H12A zinc finger CCCH-type containing 12A
ZNF165 zinc finger protein 165
ZNF205 zinc finger protein 205
ZNF358 zinc finger protein 358
ZNF480 zinc finger protein 480