epo Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description erythropoietin|This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2056)
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Genes

75 genes co-occuring with the biological term epo in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACTN3 actinin, alpha 3 (gene/pseudogene)
ANKH ANKH inorganic pyrophosphate transport regulator
ASIC3 acid sensing (proton gated) ion channel 3
ATF4 activating transcription factor 4
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
CCL3 chemokine (C-C motif) ligand 3
CGB chorionic gonadotropin, beta polypeptide
CREB1 cAMP responsive element binding protein 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
EGLN1 egl-9 family hypoxia-inducible factor 1
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
EPO erythropoietin
EPOR erythropoietin receptor
EPX eosinophil peroxidase
FABP1 fatty acid binding protein 1, liver
FAS Fas cell surface death receptor
FLT1 fms-related tyrosine kinase 1
FOXO3 forkhead box O3
GATA2 GATA binding protein 2
GATA3 GATA binding protein 3
GATA4 GATA binding protein 4
GDF15 growth differentiation factor 15
HAMP hepcidin antimicrobial peptide
HFE2 hemochromatosis type 2 (juvenile)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
HSPA9 heat shock 70kDa protein 9 (mortalin)
IFNG interferon, gamma
IL1B interleukin 1, beta
IL6 interleukin 6
IL9 interleukin 9
KDR kinase insert domain receptor
KITLG KIT ligand
LPO lactoperoxidase
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MECOM MDS1 and EVI1 complex locus
MPL MPL proto-oncogene, thrombopoietin receptor
MPO myeloperoxidase
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFE2 nuclear factor, erythroid 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS3 nitric oxide synthase 3 (endothelial cell)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PTHLH parathyroid hormone-like hormone
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN6 protein tyrosine phosphatase, non-receptor type 6
SGK1 serum/glucocorticoid regulated kinase 1
SIRT1 sirtuin 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
TAL1 T-cell acute lymphocytic leukemia 1
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
THPO thrombopoietin
TNF tumor necrosis factor
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TTR transthyretin
USF2 upstream transcription factor 2, c-fos interacting
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WT1 Wilms tumor 1