epor Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description erythropoietin receptor|This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 2057)
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Genes

22 genes co-occuring with the biological term epor in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
EPHB4 EPH receptor B4
EPO erythropoietin
EPOR erythropoietin receptor
ESR1 estrogen receptor 1
ETV6 ets variant 6
GPER1 G protein-coupled estrogen receptor 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-G major histocompatibility complex, class I, G
HSPA4 heat shock 70kDa protein 4
IGH immunoglobulin heavy locus
JAK2 Janus kinase 2
KITLG KIT ligand
LYN LYN proto-oncogene, Src family tyrosine kinase
MECOM MDS1 and EVI1 complex locus
MPL MPL proto-oncogene, thrombopoietin receptor
RUNX1 runt-related transcription factor 1
SOCS3 suppressor of cytokine signaling 3
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TAL1 T-cell acute lymphocytic leukemia 1
WT1 Wilms tumor 1