eps15 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description epidermal growth factor receptor pathway substrate 15|This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2009] (NCBI Entrez Gene Database, 2060)
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Genes

11 genes co-occuring with the biological term eps15 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
APP amyloid beta (A4) precursor protein
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
EGFR epidermal growth factor receptor
EPS15 epidermal growth factor receptor pathway substrate 15
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
MAPK14 mitogen-activated protein kinase 14
MET MET proto-oncogene, receptor tyrosine kinase
PARK2 parkin RBR E3 ubiquitin protein ligase
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1
WWP1 WW domain containing E3 ubiquitin protein ligase 1