equilin-3039 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the equilin-3039 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ADAM7 ADAM metallopeptidase domain 7
AK1 adenylate kinase 1
AREG amphiregulin
ARHGAP26 Rho GTPase activating protein 26
ASCL1 achaete-scute family bHLH transcription factor 1
ATP9A ATPase, class II, type 9A
BTN3A1 butyrophilin, subfamily 3, member A1
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CCDC181 coiled-coil domain containing 181
CD209 CD209 molecule
CD22 CD22 molecule
CD68 CD68 molecule
CLDN3 claudin 3
COL1A1 collagen, type I, alpha 1
DRD2 dopamine receptor D2
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
DZIP3 DAZ interacting zinc finger protein 3
EGLN3 egl-9 family hypoxia-inducible factor 3
EGOT eosinophil granule ontogeny transcript (non-protein coding)
ESR1 estrogen receptor 1
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAM149B1 family with sequence similarity 149, member B1
FAM65B family with sequence similarity 65, member B
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGF16 fibroblast growth factor 16
FRMD8 FERM domain containing 8
GABARAPL1 GABA(A) receptor-associated protein like 1
GALC galactosylceramidase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPR153 G protein-coupled receptor 153
GRIK5 glutamate receptor, ionotropic, kainate 5
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HCFC1 host cell factor C1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HOXA1 homeobox A1
IL36RN interleukin 36 receptor antagonist
IMPG2 interphotoreceptor matrix proteoglycan 2
IRF4 interferon regulatory factor 4
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KRT8 keratin 8, type II
KRTAP1-3 keratin associated protein 1-3
LMOD1 leiomodin 1 (smooth muscle)
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP9 microtubule-associated protein 9
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MED16 mediator complex subunit 16
MIR622 microRNA 622
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MRPL20 mitochondrial ribosomal protein L20
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MUSK muscle, skeletal, receptor tyrosine kinase
MYH14 myosin, heavy chain 14, non-muscle
MYO7B myosin VIIB
NEUROG2 neurogenin 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NIPAL3 NIPA-like domain containing 3
NPR1 natriuretic peptide receptor 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NXPE4 neurexophilin and PC-esterase domain family, member 4
OCA2 oculocutaneous albinism II
PBOV1 prostate and breast cancer overexpressed 1
PCDHB17P protocadherin beta 17 pseudogene
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PDLIM7 PDZ and LIM domain 7 (enigma)
PKNOX2 PBX/knotted 1 homeobox 2
PP14571 uncharacterized LOC100130449
PRPH peripherin
PTGDS prostaglandin D2 synthase 21kDa (brain)
QPCTL glutaminyl-peptide cyclotransferase-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RELN reelin
RIMS2 regulating synaptic membrane exocytosis 2
RPL10L ribosomal protein L10-like
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RUNDC3A RUN domain containing 3A
SCIN scinderin
SCN7A sodium channel, voltage gated, type VII alpha subunit
SEZ6L seizure related 6 homolog (mouse)-like
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SNPH syntaphilin
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STX11 syntaxin 11
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TBX5 T-box 5
TCEAL2 transcription elongation factor A (SII)-like 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TCP10L t-complex 10-like
TGFBR3 transforming growth factor, beta receptor III
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TSKU tsukushi, small leucine rich proteoglycan
TUBA4B tubulin, alpha 4b
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ANKRD55 ankyrin repeat domain 55
AP4M1 adaptor-related protein complex 4, mu 1 subunit
AXIN1 axin 1
BSPRY B-box and SPRY domain containing
C14ORF93 chromosome 14 open reading frame 93
C17ORF70 chromosome 17 open reading frame 70
C22ORF46 chromosome 22 open reading frame 46
C8A complement component 8, alpha polypeptide
C9ORF9 chromosome 9 open reading frame 9
CDHR2 cadherin-related family member 2
CFAP69 cilia and flagella associated protein 69
CFP complement factor properdin
CHMP1A charged multivesicular body protein 1A
CHPF chondroitin polymerizing factor
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLGN calmegin
CPNE7 copine VII
CRYGC crystallin, gamma C
DYSF dysferlin
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EGR2 early growth response 2
EIF5A2 eukaryotic translation initiation factor 5A2
ELAVL3 ELAV like neuron-specific RNA binding protein 3
FAM106A family with sequence similarity 106, member A
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FHL3 four and a half LIM domains 3
FOXN2 forkhead box N2
FRMPD1 FERM and PDZ domain containing 1
FURIN furin (paired basic amino acid cleaving enzyme)
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GBP2 guanylate binding protein 2, interferon-inducible
GIF gastric intrinsic factor (vitamin B synthesis)
HIST1H1B histone cluster 1, H1b
HS1BP3 HCLS1 binding protein 3
IBSP integrin-binding sialoprotein
IDI2-AS1 IDI2 antisense RNA 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IRF7 interferon regulatory factor 7
ITGA10 integrin, alpha 10
ITPKB inositol-trisphosphate 3-kinase B
KDM8 lysine (K)-specific demethylase 8
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KLF3 Kruppel-like factor 3 (basic)
KLHL36 kelch-like family member 36
KRT8P12 keratin 8 pseudogene 12
LIN7A lin-7 homolog A (C. elegans)
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTB lymphotoxin beta (TNF superfamily, member 3)
MICA MHC class I polypeptide-related sequence A
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NDE1 nudE neurodevelopment protein 1
NIPAL2 NIPA-like domain containing 2
NME8 NME/NM23 family member 8
OCLN occludin
OXCT2 3-oxoacid CoA transferase 2
PADI1 peptidyl arginine deiminase, type I
PDGFD platelet derived growth factor D
PDGFRL platelet-derived growth factor receptor-like
PDZD7 PDZ domain containing 7
PHACTR1 phosphatase and actin regulator 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PMFBP1 polyamine modulated factor 1 binding protein 1
POLM polymerase (DNA directed), mu
PRSS21 protease, serine, 21 (testisin)
PTCD1 pentatricopeptide repeat domain 1
QSER1 glutamine and serine rich 1
RAB33A RAB33A, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
REC8 REC8 meiotic recombination protein
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHOB ras homolog family member B
RPGRIP1L RPGRIP1-like
RPL13P5 ribosomal protein L13 pseudogene 5
SCG5 secretogranin V
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SH2D4A SH2 domain containing 4A
SLC16A4 solute carrier family 16, member 4
SLC17A2 solute carrier family 17, member 2
SLC35F5 solute carrier family 35, member F5
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMR3B submaxillary gland androgen regulated protein 3B
SPATA20 spermatogenesis associated 20
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM209 transmembrane protein 209
TMEM53 transmembrane protein 53
TONSL tonsoku-like, DNA repair protein
TRAF2 TNF receptor-associated factor 2
TRIM36 tripartite motif containing 36
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TRPS1 trichorhinophalangeal syndrome I
TTLL1 tubulin tyrosine ligase-like family member 1
ZNF212 zinc finger protein 212
ZNF768 zinc finger protein 768