| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the equilin-4659 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACRV1 | acrosomal vesicle protein 1 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| ADAM20 | ADAM metallopeptidase domain 20 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| APOB | apolipoprotein B |
| ATXN7L1 | ataxin 7-like 1 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| C2CD2L | C2CD2-like |
| C6ORF10 | chromosome 6 open reading frame 10 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CHAT | choline O-acetyltransferase |
| CHI3L2 | chitinase 3-like 2 |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CORT | cortistatin |
| CPB1 | carboxypeptidase B1 (tissue) |
| CRMP1 | collapsin response mediator protein 1 |
| CRYGD | crystallin, gamma D |
| DCTN1 | dynactin 1 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EMID1 | EMI domain containing 1 |
| ENG | endoglin |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| ETV6 | ets variant 6 |
| EXO5 | exonuclease 5 |
| EXOSC1 | exosome component 1 |
| FAM63B | family with sequence similarity 63, member B |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| FMOD | fibromodulin |
| FOXO1 | forkhead box O1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAL | galanin/GMAP prepropeptide |
| GLI2 | GLI family zinc finger 2 |
| GNRHR | gonadotropin-releasing hormone receptor |
| GPR75 | G protein-coupled receptor 75 |
| GRM8 | glutamate receptor, metabotropic 8 |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HGD | homogentisate 1,2-dioxygenase |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HR | hair growth associated |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IL16 | interleukin 16 |
| ING2 | inhibitor of growth family, member 2 |
| KIR3DS1 | killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 |
| KLF6 | Kruppel-like factor 6 |
| KRT17 | keratin 17, type I |
| LIPE | lipase, hormone-sensitive |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| MCPH1 | microcephalin 1 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MPPE1 | metallophosphoesterase 1 |
| MTAP | methylthioadenosine phosphorylase |
| MTMR1 | myotubularin related protein 1 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MVD | mevalonate (diphospho) decarboxylase |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NPVF | neuropeptide VF precursor |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| PAX9 | paired box 9 |
| PCDHB3 | protocadherin beta 3 |
| PCDHGB6 | protocadherin gamma subfamily B, 6 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| RBM12B | RNA binding motif protein 12B |
| RCVRN | recoverin |
| RPL10L | ribosomal protein L10-like |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| RS1 | retinoschisin 1 |
| SAA3P | serum amyloid A3 pseudogene |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SPON1 | spondin 1, extracellular matrix protein |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
| SRPK3 | SRSF protein kinase 3 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| SULF1 | sulfatase 1 |
| SYMPK | symplekin |
| SYN3 | synapsin III |
| TTC22 | tetratricopeptide repeat domain 22 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF749 | zinc finger protein 749 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| AGO4 | argonaute RISC catalytic component 4 |
| AMT | aminomethyltransferase |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| ATAD5 | ATPase family, AAA domain containing 5 |
| AURKC | aurora kinase C |
| AXIN1 | axin 1 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C1RL | complement component 1, r subcomponent-like |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CA9 | carbonic anhydrase IX |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CEP97 | centrosomal protein 97kDa |
| CHMP6 | charged multivesicular body protein 6 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CREB5 | cAMP responsive element binding protein 5 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EML4 | echinoderm microtubule associated protein like 4 |
| FAM53B | family with sequence similarity 53, member B |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FUZ | fuzzy planar cell polarity protein |
| GAS8 | growth arrest-specific 8 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GPR3 | G protein-coupled receptor 3 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HLX | H2.0-like homeobox |
| IFT140 | intraflagellar transport 140 |
| IFT54 | intraflagellar transport 54 |
| IL17RA | interleukin 17 receptor A |
| IL24 | interleukin 24 |
| IL32 | interleukin 32 |
| INADL | InaD-like (Drosophila) |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KIAA1462 | KIAA1462 |
| KLF2 | Kruppel-like factor 2 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL25 | kelch-like family member 25 |
| KRT4 | keratin 4, type II |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LMO7 | LIM domain 7 |
| MCC | mutated in colorectal cancers |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MX1 | MX dynamin-like GTPase 1 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NAG18 | NAG18 mRNA |
| NDP | Norrie disease (pseudoglioma) |
| NDRG4 | NDRG family member 4 |
| NOL10 | nucleolar protein 10 |
| NRTN | neurturin |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| RUNDC3B | RUN domain containing 3B |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH2D4A | SH2 domain containing 4A |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SP1 | Sp1 transcription factor |
| SPEG | SPEG complex locus |
| SPRYD7 | SPRY domain containing 7 |
| STAC | SH3 and cysteine rich domain |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STK16 | serine/threonine kinase 16 |
| SYNGR3 | synaptogyrin 3 |
| SYT17 | synaptotagmin XVII |
| TCTN2 | tectonic family member 2 |
| TMEM8B | transmembrane protein 8B |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TUBA4B | tubulin, alpha 4b |
| UBTD1 | ubiquitin domain containing 1 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF219 | zinc finger protein 219 |
| ZNF276 | zinc finger protein 276 |
| ZNF778 | zinc finger protein 778 |