| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the equilin-5255 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ARTN | artemin |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C1QB | complement component 1, q subcomponent, B chain |
| C3 | complement component 3 |
| CCDC70 | coiled-coil domain containing 70 |
| CD52 | CD52 molecule |
| CD58 | CD58 molecule |
| CD6 | CD6 molecule |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CLEC11A | C-type lectin domain family 11, member A |
| CRMP1 | collapsin response mediator protein 1 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DMPK | dystrophia myotonica-protein kinase |
| DMXL2 | Dmx-like 2 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DOK2 | docking protein 2, 56kDa |
| DVL2 | dishevelled segment polarity protein 2 |
| EGR3 | early growth response 3 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| EPHB2 | EPH receptor B2 |
| ETV5 | ets variant 5 |
| EXOSC1 | exosome component 1 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FBXO2 | F-box protein 2 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FOXG1 | forkhead box G1 |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GHRHR | growth hormone releasing hormone receptor |
| GLS | glutaminase |
| GPR3 | G protein-coupled receptor 3 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HHAT | hedgehog acyltransferase |
| ICOSLG | inducible T-cell co-stimulator ligand |
| INO80D | INO80 complex subunit D |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| JAK2 | Janus kinase 2 |
| KIAA0125 | KIAA0125 |
| KLHL20 | kelch-like family member 20 |
| LIFR | leukemia inhibitory factor receptor alpha |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LTC4S | leukotriene C4 synthase |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAGEA3 | melanoma antigen family A3 |
| MAOA | monoamine oxidase A |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MEF2D | myocyte enhancer factor 2D |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MINK1 | misshapen-like kinase 1 |
| MOB3B | MOB kinase activator 3B |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| MTMR7 | myotubularin related protein 7 |
| MX1 | MX dynamin-like GTPase 1 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NAA11 | N(alpha)-acetyltransferase 11, NatA catalytic subunit |
| NAV2 | neuron navigator 2 |
| NF1 | neurofibromin 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NKX2-5 | NK2 homeobox 5 |
| NMRK1 | nicotinamide riboside kinase 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| NPR3 | natriuretic peptide receptor 3 |
| OMG | oligodendrocyte myelin glycoprotein |
| PCDHB11 | protocadherin beta 11 |
| PEX5L | peroxisomal biogenesis factor 5-like |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| RAB6A | RAB6A, member RAS oncogene family |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RNF208 | ring finger protein 208 |
| RSU1 | Ras suppressor protein 1 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SHOX2 | short stature homeobox 2 |
| SLC43A3 | solute carrier family 43, member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPN | sialophorin |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) |
| TBKBP1 | TBK1 binding protein 1 |
| TGM2 | transglutaminase 2 |
| THRB | thyroid hormone receptor, beta |
| TLR1 | toll-like receptor 1 |
| TMOD2 | tropomodulin 2 (neuronal) |
| TNXB | tenascin XB |
| TREM2 | triggering receptor expressed on myeloid cells 2 |
| TTC39A | tetratricopeptide repeat domain 39A |
| ZFAND5 | zinc finger, AN1-type domain 5 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| B9D2 | B9 protein domain 2 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CCDC25 | coiled-coil domain containing 25 |
| CEP295 | centrosomal protein 295kDa |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLGN | calmegin |
| CLSPN | claspin |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CXADR | coxsackie virus and adenovirus receptor |
| CXXC4 | CXXC finger protein 4 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EFNA1 | ephrin-A1 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EPHA4 | EPH receptor A4 |
| ETNK2 | ethanolamine kinase 2 |
| ETV6 | ets variant 6 |
| FBXO31 | F-box protein 31 |
| FGF13 | fibroblast growth factor 13 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FRMD1 | FERM domain containing 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GK3P | glycerol kinase 3 pseudogene |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPATCH2L | G patch domain containing 2-like |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H4F | histone cluster 1, H4f |
| HOXC8 | homeobox C8 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HYI | hydroxypyruvate isomerase (putative) |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IRF1 | interferon regulatory factor 1 |
| IRF9 | interferon regulatory factor 9 |
| ITGA10 | integrin, alpha 10 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIF5A | kinesin family member 5A |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MYOZ3 | myozenin 3 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NDRG1 | N-myc downstream regulated 1 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NME5 | NME/NM23 family member 5 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPTX1 | neuronal pentraxin I |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PCDHB13 | protocadherin beta 13 |
| PGP | phosphoglycolate phosphatase |
| PRR4 | proline rich 4 (lacrimal) |
| PRSS53 | protease, serine, 53 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| RAB3D | RAB3D, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPL10L | ribosomal protein L10-like |
| S100A7 | S100 calcium binding protein A7 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAI | suppressor of cancer cell invasion |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STRA6 | stimulated by retinoic acid 6 |
| TARP | TCR gamma alternate reading frame protein |
| TCTA | T-cell leukemia translocation altered |
| TMEM53 | transmembrane protein 53 |
| TMEM57 | transmembrane protein 57 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TYRP1 | tyrosinase-related protein 1 |
| USB1 | U6 snRNA biogenesis 1 |
| VEGFC | vascular endothelial growth factor C |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF329 | zinc finger protein 329 |
| ZNF428 | zinc finger protein 428 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |