equilin-5255 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the equilin-5255 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP8L A kinase (PRKA) anchor protein 8-like
ARTN artemin
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
C19ORF66 chromosome 19 open reading frame 66
C1QB complement component 1, q subcomponent, B chain
C3 complement component 3
CCDC70 coiled-coil domain containing 70
CD52 CD52 molecule
CD58 CD58 molecule
CD6 CD6 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLEC11A C-type lectin domain family 11, member A
CRMP1 collapsin response mediator protein 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DMPK dystrophia myotonica-protein kinase
DMXL2 Dmx-like 2
DNALI1 dynein, axonemal, light intermediate chain 1
DOK2 docking protein 2, 56kDa
DVL2 dishevelled segment polarity protein 2
EGR3 early growth response 3
EHBP1L1 EH domain binding protein 1-like 1
EPHB2 EPH receptor B2
ETV5 ets variant 5
EXOSC1 exosome component 1
F5 coagulation factor V (proaccelerin, labile factor)
FBXO2 F-box protein 2
FGFR1 fibroblast growth factor receptor 1
FOXG1 forkhead box G1
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GHRHR growth hormone releasing hormone receptor
GLS glutaminase
GPR3 G protein-coupled receptor 3
GRIK5 glutamate receptor, ionotropic, kainate 5
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HHAT hedgehog acyltransferase
ICOSLG inducible T-cell co-stimulator ligand
INO80D INO80 complex subunit D
IPW imprinted in Prader-Willi syndrome (non-protein coding)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAK2 Janus kinase 2
KIAA0125 KIAA0125
KLHL20 kelch-like family member 20
LIFR leukemia inhibitory factor receptor alpha
LINC00341 long intergenic non-protein coding RNA 341
LTC4S leukotriene C4 synthase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGEA3 melanoma antigen family A3
MAOA monoamine oxidase A
MARK2 MAP/microtubule affinity-regulating kinase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEF2D myocyte enhancer factor 2D
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MIER2 mesoderm induction early response 1, family member 2
MINK1 misshapen-like kinase 1
MOB3B MOB kinase activator 3B
MTL5 metallothionein-like 5, testis-specific (tesmin)
MTMR7 myotubularin related protein 7
MX1 MX dynamin-like GTPase 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit
NAV2 neuron navigator 2
NF1 neurofibromin 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKX2-5 NK2 homeobox 5
NMRK1 nicotinamide riboside kinase 1
NPC1 Niemann-Pick disease, type C1
NPR3 natriuretic peptide receptor 3
OMG oligodendrocyte myelin glycoprotein
PCDHB11 protocadherin beta 11
PEX5L peroxisomal biogenesis factor 5-like
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PKNOX2 PBX/knotted 1 homeobox 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
RAB6A RAB6A, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RNF208 ring finger protein 208
RSU1 Ras suppressor protein 1
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SHOX2 short stature homeobox 2
SLC43A3 solute carrier family 43, member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
SPN sialophorin
SRF serum response factor (c-fos serum response element-binding transcription factor)
TBKBP1 TBK1 binding protein 1
TGM2 transglutaminase 2
THRB thyroid hormone receptor, beta
TLR1 toll-like receptor 1
TMOD2 tropomodulin 2 (neuronal)
TNXB tenascin XB
TREM2 triggering receptor expressed on myeloid cells 2
TTC39A tetratricopeptide repeat domain 39A
ZFAND5 zinc finger, AN1-type domain 5
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
AGMAT agmatine ureohydrolase (agmatinase)
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARC activity-regulated cytoskeleton-associated protein
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ASPHD1 aspartate beta-hydroxylase domain containing 1
B9D2 B9 protein domain 2
C8ORF60 chromosome 8 open reading frame 60
CCDC25 coiled-coil domain containing 25
CEP295 centrosomal protein 295kDa
CLCN6 chloride channel, voltage-sensitive 6
CLGN calmegin
CLSPN claspin
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COPZ2 coatomer protein complex, subunit zeta 2
CXADR coxsackie virus and adenovirus receptor
CXXC4 CXXC finger protein 4
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFNA1 ephrin-A1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA4 EPH receptor A4
ETNK2 ethanolamine kinase 2
ETV6 ets variant 6
FBXO31 F-box protein 31
FGF13 fibroblast growth factor 13
FKBP10 FK506 binding protein 10, 65 kDa
FRMD1 FERM domain containing 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAMT guanidinoacetate N-methyltransferase
GK3P glycerol kinase 3 pseudogene
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH2L G patch domain containing 2-like
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H4F histone cluster 1, H4f
HOXC8 homeobox C8
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HYI hydroxypyruvate isomerase (putative)
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IGFBP6 insulin-like growth factor binding protein 6
IRF1 interferon regulatory factor 1
IRF9 interferon regulatory factor 9
ITGA10 integrin, alpha 10
KDM5C lysine (K)-specific demethylase 5C
KIF5A kinesin family member 5A
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MYOZ3 myozenin 3
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDRG1 N-myc downstream regulated 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NME5 NME/NM23 family member 5
NPFFR1 neuropeptide FF receptor 1
NPTX1 neuronal pentraxin I
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSGIN1 oxidative stress induced growth inhibitor 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCDHB13 protocadherin beta 13
PGP phosphoglycolate phosphatase
PRR4 proline rich 4 (lacrimal)
PRSS53 protease, serine, 53
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RAB3D RAB3D, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL10L ribosomal protein L10-like
S100A7 S100 calcium binding protein A7
SAYSD1 SAYSVFN motif domain containing 1
SCAI suppressor of cancer cell invasion
SCML2 sex comb on midleg-like 2 (Drosophila)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC12A9 solute carrier family 12, member 9
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STRA6 stimulated by retinoic acid 6
TARP TCR gamma alternate reading frame protein
TCTA T-cell leukemia translocation altered
TMEM53 transmembrane protein 53
TMEM57 transmembrane protein 57
TMPRSS2 transmembrane protease, serine 2
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TYRP1 tyrosinase-related protein 1
USB1 U6 snRNA biogenesis 1
VEGFC vascular endothelial growth factor C
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF329 zinc finger protein 329
ZNF428 zinc finger protein 428
ZSWIM1 zinc finger, SWIM-type containing 1