er-associated ubiquitin-dependent protein catabolic process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the breakdown of proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation. This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. (Gene Ontology, GO_0030433)
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41 genes participating in the er-associated ubiquitin-dependent protein catabolic process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
DERL1 derlin 1
DERL2 derlin 2
DERL3 derlin 3
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
ERLIN1 ER lipid raft associated 1
ERLIN2 ER lipid raft associated 2
FBXO2 F-box protein 2
FBXO6 F-box protein 6
FOXRED2 FAD-dependent oxidoreductase domain containing 2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
JKAMP JNK1/MAPK8-associated membrane protein
KIAA0368 KIAA0368
MAN1B1 mannosidase, alpha, class 1B, member 1
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin
RHBDD1 rhomboid domain containing 1
RNF103 ring finger protein 103
RNF121 ring finger protein 121
RNF175 ring finger protein 175
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
SDF2L1 stromal cell-derived factor 2-like 1
SEC61B Sec61 beta subunit
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TMEM67 transmembrane protein 67
TOR1A torsin family 1, member A (torsin A)
TRIM13 tripartite motif containing 13
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UBE2J2 ubiquitin-conjugating enzyme E2, J2
UBXN8 UBX domain protein 8
USP19 ubiquitin specific peptidase 19
VCP valosin containing protein
VIMP VCP-interacting membrane selenoprotein
WFS1 Wolfram syndrome 1 (wolframin)
YOD1 YOD1 deubiquitinase