erap1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description endoplasmic reticulum aminopeptidase 1|The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010] (NCBI Entrez Gene Database, 51752)
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Genes

18 genes co-occuring with the biological term erap1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
CANX calnexin
ERAP1 endoplasmic reticulum aminopeptidase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
ESR1 estrogen receptor 1
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
IL23R interleukin 23 receptor
JUN jun proto-oncogene
LNPEP leucyl/cystinyl aminopeptidase
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
PDIA3 protein disulfide isomerase family A, member 3
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBPL TAP binding protein-like
TP53 tumor protein p53