| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the erastin-6364 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACRV1 | acrosomal vesicle protein 1 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| ALOX12 | arachidonate 12-lipoxygenase |
| ALOX12B | arachidonate 12-lipoxygenase, 12R type |
| ALOX5 | arachidonate 5-lipoxygenase |
| AMPD1 | adenosine monophosphate deaminase 1 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ARSA | arylsulfatase A |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| C1ORF61 | chromosome 1 open reading frame 61 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CAPN10 | calpain 10 |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CD52 | CD52 molecule |
| CDC5L | cell division cycle 5-like |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLIC5 | chloride intracellular channel 5 |
| COL16A1 | collagen, type XVI, alpha 1 |
| CPA4 | carboxypeptidase A4 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DCAKD | dephospho-CoA kinase domain containing |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DTNB | dystrobrevin, beta |
| DYM | dymeclin |
| EXOSC2 | exosome component 2 |
| FCAR | Fc fragment of IgA receptor |
| FLOT1 | flotillin 1 |
| FRMD1 | FERM domain containing 1 |
| FRZB | frizzled-related protein |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GPX2 | glutathione peroxidase 2 |
| GRM2 | glutamate receptor, metabotropic 2 |
| HFE | hemochromatosis |
| HHAT | hedgehog acyltransferase |
| HOXA10 | homeobox A10 |
| HOXA4 | homeobox A4 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase |
| IL11 | interleukin 11 |
| INHBE | inhibin, beta E |
| KCNJ14 | potassium channel, inwardly rectifying subfamily J, member 14 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIFC3 | kinesin family member C3 |
| KLF12 | Kruppel-like factor 12 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LAT2 | linker for activation of T cells family, member 2 |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LMTK1 | lemur tail kinase 1 |
| MCF2L2 | MCF.2 cell line derived transforming sequence-like 2 |
| MED25 | mediator complex subunit 25 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NME5 | NME/NM23 family member 5 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PCDHB12 | protocadherin beta 12 |
| PDE8B | phosphodiesterase 8B |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PLCB2 | phospholipase C, beta 2 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| RARB | retinoic acid receptor, beta |
| RASAL2 | RAS protein activator like 2 |
| RPL7 | ribosomal protein L7 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SHOX2 | short stature homeobox 2 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC13A2 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNTG1 | syntrophin, gamma 1 |
| SPN | sialophorin |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| STAB1 | stabilin 1 |
| STK24 | serine/threonine kinase 24 |
| STOML1 | stomatin (EPB72)-like 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TAOK1 | TAO kinase 1 |
| TCF4 | transcription factor 4 |
| TENM4 | teneurin transmembrane protein 4 |
| TLR2 | toll-like receptor 2 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TSSK2 | testis-specific serine kinase 2 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZNF646 | zinc finger protein 646 |
| ZNF771 | zinc finger protein 771 |
| Symbol | Name |
|---|---|
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AQP7 | aquaporin 7 |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ATG10 | autophagy related 10 |
| BST1 | bone marrow stromal cell antigen 1 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| CCL16 | chemokine (C-C motif) ligand 16 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CD244 | CD244 molecule, natural killer cell receptor 2B4 |
| CDON | cell adhesion associated, oncogene regulated |
| CFP | complement factor properdin |
| COL9A1 | collagen, type IX, alpha 1 |
| CPLX2 | complexin 2 |
| CRYGD | crystallin, gamma D |
| CT55 | cancer/testis antigen 55 |
| CTSE | cathepsin E |
| DOK5 | docking protein 5 |
| DSPP | dentin sialophosphoprotein |
| ELAVL4 | ELAV like neuron-specific RNA binding protein 4 |
| EPHB6 | EPH receptor B6 |
| ETV4 | ets variant 4 |
| EXTL1 | exostosin-like glycosyltransferase 1 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 |
| FOXJ1 | forkhead box J1 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GPR183 | G protein-coupled receptor 183 |
| GPR3 | G protein-coupled receptor 3 |
| GRM4 | glutamate receptor, metabotropic 4 |
| GTPBP10 | GTP-binding protein 10 (putative) |
| HAMP | hepcidin antimicrobial peptide |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HEYL | hes-related family bHLH transcription factor with YRPW motif-like |
| HIST1H2AI | histone cluster 1, H2ai |
| HOXB2 | homeobox B2 |
| HSF4 | heat shock transcription factor 4 |
| INE1 | inactivation escape 1 (non-protein coding) |
| KCNA2 | potassium channel, voltage gated shaker related subfamily A, member 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KLHL25 | kelch-like family member 25 |
| KLK12 | kallikrein-related peptidase 12 |
| KRT38 | keratin 38, type I |
| KRT83 | keratin 83, type II |
| LEFTY1 | left-right determination factor 1 |
| LIM2 | lens intrinsic membrane protein 2, 19kDa |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LSP1 | lymphocyte-specific protein 1 |
| LYZ | lysozyme |
| MALL | mal, T-cell differentiation protein-like |
| MCC | mutated in colorectal cancers |
| MMP10 | matrix metallopeptidase 10 |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| MXRA8 | matrix-remodelling associated 8 |
| MYLK | myosin light chain kinase |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NNAT | neuronatin |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NTN3 | netrin 3 |
| PAX1 | paired box 1 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLG | plasminogen |
| PRO2964 | uncharacterized protein PRO2964 |
| PROX1 | prospero homeobox 1 |
| PTPRN | protein tyrosine phosphatase, receptor type, N |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| ROR2 | receptor tyrosine kinase-like orphan receptor 2 |
| RPS2P45 | ribosomal protein S2 pseudogene 45 |
| SKI | SKI proto-oncogene |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 |
| SLCO1B1 | solute carrier organic anion transporter family, member 1B1 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SSTR5 | somatostatin receptor 5 |
| STMN4 | stathmin-like 4 |
| STRN | striatin, calmodulin binding protein |
| T | T, brachyury homolog (mouse) |
| TAT | tyrosine aminotransferase |
| TCTN2 | tectonic family member 2 |
| TMEM8B | transmembrane protein 8B |
| TONSL | tonsoku-like, DNA repair protein |
| TRIM58 | tripartite motif containing 58 |
| XDH | xanthine dehydrogenase |
| ZBTB7B | zinc finger and BTB domain containing 7B |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF428 | zinc finger protein 428 |
| ZNF506 | zinc finger protein 506 |
| ZNF639 | zinc finger protein 639 |
