| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
195 genes differentially expressed following the erastin-6369 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX3 | acyl-CoA oxidase 3, pristanoyl |
| ACVR1B | activin A receptor, type IB |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BEND5 | BEN domain containing 5 |
| BTBD18 | BTB (POZ) domain containing 18 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| CADM4 | cell adhesion molecule 4 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC85B | coiled-coil domain containing 85B |
| CCR2 | chemokine (C-C motif) receptor 2 |
| CD200 | CD200 molecule |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEP41 | centrosomal protein 41kDa |
| CERS4 | ceramide synthase 4 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COL6A1 | collagen, type VI, alpha 1 |
| COPE | coatomer protein complex, subunit epsilon |
| CORO7 | coronin 7 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSPG5 | chondroitin sulfate proteoglycan 5 (neuroglycan C) |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DCTN1 | dynactin 1 |
| DCX | doublecortin |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DTNA | dystrobrevin, alpha |
| DTNB | dystrobrevin, beta |
| EDNRA | endothelin receptor type A |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| ELL | elongation factor RNA polymerase II |
| FAM49B | family with sequence similarity 49, member B |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FYB | FYN binding protein |
| GIMAP5 | GTPase, IMAP family member 5 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HEMK1 | HemK methyltransferase family member 1 |
| HIP1 | huntingtin interacting protein 1 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HOXB2 | homeobox B2 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| INHBA | inhibin, beta A |
| ISG20L2 | interferon stimulated exonuclease gene 20kDa-like 2 |
| KCND1 | potassium channel, voltage gated Shal related subfamily D, member 1 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNJ12 | potassium channel, inwardly rectifying subfamily J, member 12 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KIAA0391 | KIAA0391 |
| KIAA1549L | KIAA1549-like |
| KIF2A | kinesin heavy chain member 2A |
| KLF13 | Kruppel-like factor 13 |
| KRT32 | keratin 32, type I |
| KRT6B | keratin 6B, type II |
| KYNU | kynureninase |
| LOC100131532 | uncharacterized LOC100131532 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MIIP | migration and invasion inhibitory protein |
| NOX1 | NADPH oxidase 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| RABIF | RAB interacting factor |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| RPL18 | ribosomal protein L18 |
| RUNX1 | runt-related transcription factor 1 |
| SAA3P | serum amyloid A3 pseudogene |
| SIX3 | SIX homeobox 3 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SOCS3 | suppressor of cytokine signaling 3 |
| SYT1 | synaptotagmin I |
| TFEB | transcription factor EB |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TMEM212 | transmembrane protein 212 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TPM2 | tropomyosin 2 (beta) |
| TRIM45 | tripartite motif containing 45 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF444 | zinc finger protein 444 |
| ZNF518A | zinc finger protein 518A |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ATG10 | autophagy related 10 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| BMPR1B | bone morphogenetic protein receptor, type IB |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCDC57 | coiled-coil domain containing 57 |
| CD2 | CD2 molecule |
| CD300C | CD300c molecule |
| CDON | cell adhesion associated, oncogene regulated |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CEL | carboxyl ester lipase |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 |
| CLEC3B | C-type lectin domain family 3, member B |
| CLUL1 | clusterin-like 1 (retinal) |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CST4 | cystatin S |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| CYTH3 | cytohesin 3 |
| DKFZP434C153 | DKFZP434C153 protein |
| DKFZP434L187 | uncharacterized LOC26082 |
| DOK2 | docking protein 2, 56kDa |
| DOK5 | docking protein 5 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| ENO3 | enolase 3 (beta, muscle) |
| FBXO22 | F-box protein 22 |
| FBXO31 | F-box protein 31 |
| FGF21 | fibroblast growth factor 21 |
| FGL1 | fibrinogen-like 1 |
| FHL3 | four and a half LIM domains 3 |
| FOXC1 | forkhead box C1 |
| FRMD1 | FERM domain containing 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GHRH | growth hormone releasing hormone |
| GOLGA2P5 | golgin A2 pseudogene 5 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HAP1 | huntingtin-associated protein 1 |
| HCRT | hypocretin (orexin) neuropeptide precursor |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H3G | histone cluster 1, H3g |
| HTRA1 | HtrA serine peptidase 1 |
| IMPG2 | interphotoreceptor matrix proteoglycan 2 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNA2 | potassium channel, voltage gated shaker related subfamily A, member 2 |
| KIAA1456 | KIAA1456 |
| KRT85 | keratin 85, type II |
| LEFTY1 | left-right determination factor 1 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| MAOB | monoamine oxidase B |
| MATK | megakaryocyte-associated tyrosine kinase |
| MLXIPL | MLX interacting protein-like |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NRIP3 | nuclear receptor interacting protein 3 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OR10H1 | olfactory receptor, family 10, subfamily H, member 1 |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PALM | paralemmin |
| PDCD1 | programmed cell death 1 |
| PDE9A | phosphodiesterase 9A |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PIP | prolactin-induced protein |
| PMP2 | peripheral myelin protein 2 |
| PQLC2 | PQ loop repeat containing 2 |
| PRSS21 | protease, serine, 21 (testisin) |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RIMS1 | regulating synaptic membrane exocytosis 1 |
| RNF122 | ring finger protein 122 |
| SCARF1 | scavenger receptor class F, member 1 |
| SERPINF2 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SNTG1 | syntrophin, gamma 1 |
| SP1 | Sp1 transcription factor |
| SSTR4 | somatostatin receptor 4 |
| SSTR5 | somatostatin receptor 5 |
| STK16 | serine/threonine kinase 16 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TIGD6 | tigger transposable element derived 6 |
| TTN | titin |
| VNN2 | vanin 2 |
| ZNF747 | zinc finger protein 747 |
