| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the erastin-6412 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCK2 | aarF domain containing kinase 2 |
| AHNAK | AHNAK nucleoprotein |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| AMPH | amphiphysin |
| ANGPT4 | angiopoietin 4 |
| APOL3 | apolipoprotein L, 3 |
| APP | amyloid beta (A4) precursor protein |
| ARMC4 | armadillo repeat containing 4 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CASC1 | cancer susceptibility candidate 1 |
| CAV2 | caveolin 2 |
| CCR8 | chemokine (C-C motif) receptor 8 |
| CDK13 | cyclin-dependent kinase 13 |
| CENPO | centromere protein O |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLSTN3 | calsyntenin 3 |
| COL16A1 | collagen, type XVI, alpha 1 |
| COLEC12 | collectin sub-family member 12 |
| CXORF21 | chromosome X open reading frame 21 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| EPHA3 | EPH receptor A3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ESR1 | estrogen receptor 1 |
| FH | fumarate hydratase |
| FNDC3A | fibronectin type III domain containing 3A |
| FOSL2 | FOS-like antigen 2 |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) |
| GAP43 | growth associated protein 43 |
| GDPD2 | glycerophosphodiester phosphodiesterase domain containing 2 |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HFE | hemochromatosis |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H4D | histone cluster 1, H4d |
| IFNA14 | interferon, alpha 14 |
| INHBE | inhibin, beta E |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA1661 | KIAA1661 protein |
| KRTAP1-1 | keratin associated protein 1-1 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| MATN1 | matrilin 1, cartilage matrix protein |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| MYF5 | myogenic factor 5 |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OSBPL10 | oxysterol binding protein-like 10 |
| PCDHB6 | protocadherin beta 6 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PLEK | pleckstrin |
| PLIN2 | perilipin 2 |
| PLK3 | polo-like kinase 3 |
| PML | promyelocytic leukemia |
| POU2F2 | POU class 2 homeobox 2 |
| PRKCB | protein kinase C, beta |
| PRTN3 | proteinase 3 |
| PTCH1 | patched 1 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RBFA | ribosome binding factor A (putative) |
| RDH16 | retinol dehydrogenase 16 (all-trans) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RYR2 | ryanodine receptor 2 (cardiac) |
| S100A8 | S100 calcium binding protein A8 |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SDS | serine dehydratase |
| SH2D3A | SH2 domain containing 3A |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIRT5 | sirtuin 5 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLN | sarcolipin |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| ZNF528 | zinc finger protein 528 |
| ZNF695 | zinc finger protein 695 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| AFAP1 | actin filament associated protein 1 |
| ALDOAP2 | aldolase A, fructose-bisphosphate pseudogene 2 |
| AOC3 | amine oxidase, copper containing 3 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ASIC2 | acid sensing (proton gated) ion channel 2 |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| C1ORF21 | chromosome 1 open reading frame 21 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| CCDC9 | coiled-coil domain containing 9 |
| CD14 | CD14 molecule |
| CLEC4E | C-type lectin domain family 4, member E |
| CSTA | cystatin A (stefin A) |
| CT62 | cancer/testis antigen 62 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| EFNA3 | ephrin-A3 |
| ELL | elongation factor RNA polymerase II |
| EPPK1 | epiplakin 1 |
| ESM1 | endothelial cell-specific molecule 1 |
| FAM46C | family with sequence similarity 46, member C |
| FAM76A | family with sequence similarity 76, member A |
| FLT4 | fms-related tyrosine kinase 4 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GLB1L | galactosidase, beta 1-like |
| GPR143 | G protein-coupled receptor 143 |
| GPR15 | G protein-coupled receptor 15 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HDAC5 | histone deacetylase 5 |
| HEXA-AS1 | HEXA antisense RNA 1 |
| HIST1H3A | histone cluster 1, H3a |
| HOXB2 | homeobox B2 |
| HOXB3 | homeobox B3 |
| HSD17B3 | hydroxysteroid (17-beta) dehydrogenase 3 |
| IFT54 | intraflagellar transport 54 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNIP2 | Kv channel interacting protein 2 |
| KIAA1456 | KIAA1456 |
| KLHL28 | kelch-like family member 28 |
| LDB2 | LIM domain binding 2 |
| LHX1 | LIM homeobox 1 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LSP1 | lymphocyte-specific protein 1 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MBTD1 | mbt domain containing 1 |
| MDFI | MyoD family inhibitor |
| MIP | major intrinsic protein of lens fiber |
| MIR600HG | MIR600 host gene |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MS4A5 | membrane-spanning 4-domains, subfamily A, member 5 |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NME5 | NME/NM23 family member 5 |
| NRL | neural retina leucine zipper |
| ONECUT2 | one cut homeobox 2 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PALM | paralemmin |
| PCBP3 | poly(rC) binding protein 3 |
| PCDHGA11 | protocadherin gamma subfamily A, 11 |
| PCDHGA9 | protocadherin gamma subfamily A, 9 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POU3F4 | POU class 3 homeobox 4 |
| PRDM12 | PR domain containing 12 |
| PROM1 | prominin 1 |
| PRSS53 | protease, serine, 53 |
| QPCT | glutaminyl-peptide cyclotransferase |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RETN | resistin |
| RNF122 | ring finger protein 122 |
| SCG5 | secretogranin V |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC6A11 | solute carrier family 6 (neurotransmitter transporter), member 11 |
| SNTG1 | syntrophin, gamma 1 |
| SNX29 | sorting nexin 29 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TCTN2 | tectonic family member 2 |
| TDRD12 | tudor domain containing 12 |
| TLR2 | toll-like receptor 2 |
| TMEM53 | transmembrane protein 53 |
| TMEM8B | transmembrane protein 8B |
| TRAIP | TRAF interacting protein |
| TTPA | tocopherol (alpha) transfer protein |
| TUBB1 | tubulin, beta 1 class VI |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WNT8B | wingless-type MMTV integration site family, member 8B |
| XDH | xanthine dehydrogenase |
| ZNF112 | zinc finger protein 112 |
| ZNF613 | zinc finger protein 613 |
