erk1/2 Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

281 proteins co-occuring with the biological term erk1/2 in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ADAM17 ADAM metallopeptidase domain 17
ADRB2 adrenoceptor beta 2, surface
ADRBK1 adrenergic, beta, receptor kinase 1
AFAP1L2 actin filament associated protein 1-like 2
AGTR1 angiotensin II receptor, type 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALOX5 arachidonate 5-lipoxygenase
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
AQP2 aquaporin 2 (collecting duct)
AR androgen receptor
ARHGAP31 Rho GTPase activating protein 31
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
BAD BCL2-associated agonist of cell death
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCR breakpoint cluster region
BEX1 brain expressed, X-linked 1
BIK BCL2-interacting killer (apoptosis-inducing)
BLVRA biliverdin reductase A
BMPR1A bone morphogenetic protein receptor, type IA
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTG2 BTG family, member 2
BTK Bruton agammaglobulinemia tyrosine kinase
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALD1 caldesmon 1
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CANX calnexin
CASP9 caspase 9, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CCDC6 coiled-coil domain containing 6
CCKBR cholecystokinin B receptor
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR7 chemokine (C-C motif) receptor 7
CDC25A cell division cycle 25A
CDC25C cell division cycle 25C
CDK1 cyclin-dependent kinase 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDX2 caudal type homeobox 2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CENPE centromere protein E, 312kDa
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHRM2 cholinergic receptor, muscarinic 2
CIITA class II, major histocompatibility complex, transactivator
CNN3 calponin 3, acidic
CREB1 cAMP responsive element binding protein 1
CRHR1 corticotropin releasing hormone receptor 1
CRYAB crystallin, alpha B
CSF1R colony stimulating factor 1 receptor
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTTN cortactin
DAPK1 death-associated protein kinase 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK2 docking protein 2, 56kDa
DUPD1 dual specificity phosphatase and pro isomerase domain containing 1
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
DUSP9 dual specificity phosphatase 9
EGFR epidermal growth factor receptor
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ELK1 ELK1, member of ETS oncogene family
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EP300 E1A binding protein p300
EPHB1 EPH receptor B1
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV1 ets variant 1
ETV6 ets variant 6
EWSR1 EWS RNA-binding protein 1
EXOC7 exocyst complex component 7
FADD Fas (TNFRSF6)-associated via death domain
FGFR1 fibroblast growth factor receptor 1
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
FOXC1 forkhead box C1
FOXO1 forkhead box O1
FTH1 ferritin, heavy polypeptide 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GAP43 growth associated protein 43
GATA4 GATA binding protein 4
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJA1 gap junction protein, alpha 1, 43kDa
GOLGA2 golgin A2
GRB7 growth factor receptor-bound protein 7
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
H2AFX H2A histone family, member X
H3F3B H3 histone, family 3B (H3.3B)
HIST1H2BB histone cluster 1, H2bb
HIST1H3A histone cluster 1, H3a
HSF1 heat shock transcription factor 1
HSPB8 heat shock 22kDa protein 8
HTT huntingtin
IGF1R insulin-like growth factor 1 receptor
IL16 interleukin 16
IL6ST interleukin 6 signal transducer
INSR insulin receptor
IRS1 insulin receptor substrate 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB4 integrin, beta 4
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
JUND jun D proto-oncogene
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF4 Kruppel-like factor 4 (gut)
KRT8 keratin 8, type II
KSR1 kinase suppressor of ras 1
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LEPR leptin receptor
LIFR leukemia inhibitory factor receptor alpha
LIMA1 LIM domain and actin binding 1
LIME1 Lck interacting transmembrane adaptor 1
LIPE lipase, hormone-sensitive
LRP1 low density lipoprotein receptor-related protein 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK6 mitogen-activated protein kinase 6
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MBP myelin basic protein
MED1 mediator complex subunit 1
MEF2A myocyte enhancer factor 2A
MET MET proto-oncogene, receptor tyrosine kinase
MITF microphthalmia-associated transcription factor
MKL1 megakaryoblastic leukemia (translocation) 1
MKNK1 MAP kinase interacting serine/threonine kinase 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MPL MPL proto-oncogene, thrombopoietin receptor
MTMR2 myotubularin related protein 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYL12B myosin, light chain 12B, regulatory
MYOCD myocardin
NCAM1 neural cell adhesion molecule 1
NCF1 neutrophil cytosolic factor 1
NCOA3 nuclear receptor coactivator 3
NDEL1 nudE neurodevelopment protein 1-like 1
NEFL neurofilament, light polypeptide
NEUROD1 neuronal differentiation 1
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS3 nitric oxide synthase 3 (endothelial cell)
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OSMR oncostatin M receptor
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PARP1 poly (ADP-ribose) polymerase 1
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PDX1 pancreatic and duodenal homeobox 1
PEA15 phosphoprotein enriched in astrocytes 15
PEBP1 phosphatidylethanolamine binding protein 1
PGAP3 post-GPI attachment to proteins 3
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKM pyruvate kinase, muscle
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCG1 phospholipase C, gamma 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POU4F1 POU class 4 homeobox 1
POU5F1 POU class 5 homeobox 1
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCI protein kinase C, iota
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRL prolactin
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN7 protein tyrosine phosphatase, non-receptor type 7
PTPRR protein tyrosine phosphatase, receptor type, R
PXN paxillin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RGS19 regulator of G-protein signaling 19
RNF2 ring finger protein 2
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPS3 ribosomal protein S3
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RUNX2 runt-related transcription factor 2
RXRA retinoid X receptor, alpha
S100A9 S100 calcium binding protein A9
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMAD2 SMAD family member 2
SORBS3 sorbin and SH3 domain containing 3
SP1 Sp1 transcription factor
SPHK1 sphingosine kinase 1
SPHK2 sphingosine kinase 2
SPRY2 sprouty homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SREBF1 sterol regulatory element binding transcription factor 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAR steroidogenic acute regulatory protein
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STIM1 stromal interaction molecule 1
STK11 serine/threonine kinase 11
STMN1 stathmin 1
SULT4A1 sulfotransferase family 4A, member 1
SYN1 synapsin I
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TAL1 T-cell acute lymphocytic leukemia 1
TAL2 T-cell acute lymphocytic leukemia 2
TCF3 transcription factor 3
TH tyrosine hydroxylase
THRB thyroid hormone receptor, beta
TNNI3 troponin I type 3 (cardiac)
TOB1 transducer of ERBB2, 1
TP53 tumor protein p53
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC2 tuberous sclerosis 2
UBE2I ubiquitin-conjugating enzyme E2I
UBTF upstream binding transcription factor, RNA polymerase I
UBXN1 UBX domain protein 1
VIM vimentin
XBP1 X-box binding protein 1
ZC3HC1 zinc finger, C3HC-type containing 1