erk1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli. (Gene Ontology, GO_0004707)
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Genes

34 genes co-occuring with the biological term erk1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
BSG basigin (Ok blood group)
CD44 CD44 molecule (Indian blood group)
CREBBP CREB binding protein
CXCL12 chemokine (C-X-C motif) ligand 12
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ESR1 estrogen receptor 1
FGFR1 fibroblast growth factor receptor 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HSF1 heat shock transcription factor 1
HSPB8 heat shock 22kDa protein 8
IGF1 insulin-like growth factor 1 (somatomedin C)
IL4 interleukin 4
KAT2B K(lysine) acetyltransferase 2B
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MIR214 microRNA 214
MUC1 mucin 1, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
RETN resistin
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SPHK1 sphingosine kinase 1
SPHK2 sphingosine kinase 2
TGFB1 transforming growth factor, beta 1
TMPRSS4 transmembrane protease, serine 4
TNF tumor necrosis factor
VEGFA vascular endothelial growth factor A
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon