erlotinib Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
External Link http://ctdbase.org/detail.go?type=chem&acc=C400278
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Genes

47 genes/proteins interacting with the chemical erlotinib from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
AKT1 v-akt murine thymoma viral oncogene homolog 1
AREG amphiregulin
ATF4 activating transcription factor 4
ATG5 autophagy related 5
ATG7 autophagy related 7
AXL AXL receptor tyrosine kinase
BCL2 B-cell CLL/lymphoma 2
BCL2L2 BCL2-like 2
BECN1 beclin 1, autophagy related
BRCA1 breast cancer 1, early onset
CCND1 cyclin D1
CD69 CD69 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK4 cyclin-dependent kinase 4
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDIT3 DNA-damage-inducible transcript 3
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
HBEGF heparin-binding EGF-like growth factor
IFNG interferon, gamma
IL2 interleukin 2
IL2RA interleukin 2 receptor, alpha
IL6 interleukin 6
JAK2 Janus kinase 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KRAS Kirsten rat sarcoma viral oncogene homolog
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MET MET proto-oncogene, receptor tyrosine kinase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NOX4 NADPH oxidase 4
NR1I2 nuclear receptor subfamily 1, group I, member 2
PML promyelocytic leukemia
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TGFA transforming growth factor, alpha
XBP1 X-box binding protein 1