erythroderma Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An inflammatory exfoliative dermatosis involving nearly all of the surface of the skin. Erythroderma develops suddenly. A patchy erythema may generalize and spread to affect most of the skin. Scaling may appear in 2-6 days and be accompanied by hot, red, dry skin, malaise, and fever. (Human Phenotype Ontology, HP_0001019)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003454
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Genes

5 gene mutations causing the erythroderma phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CARD11 caspase recruitment domain family, member 11
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
LOR loricrin
RAG2 recombination activating gene 2
TRPV3 transient receptor potential cation channel, subfamily V, member 3