erythromycin-1510 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

192 genes differentially expressed following the erythromycin-1510 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTL8 actin-like 8
ADAM22 ADAM metallopeptidase domain 22
ADCY1 adenylate cyclase 1 (brain)
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARHGAP33 Rho GTPase activating protein 33
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMCX4 armadillo repeat containing, X-linked 4
BLZF1 basic leucine zipper nuclear factor 1
C11ORF16 chromosome 11 open reading frame 16
C22ORF46 chromosome 22 open reading frame 46
CCDC176 coiled-coil domain containing 176
CCDC33 coiled-coil domain containing 33
CD58 CD58 molecule
CDK18 cyclin-dependent kinase 18
CDK20 cyclin-dependent kinase 20
CEP152 centrosomal protein 152kDa
CFHR2 complement factor H-related 2
CNR1 cannabinoid receptor 1 (brain)
COL1A1 collagen, type I, alpha 1
DLX2 distal-less homeobox 2
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DPYSL4 dihydropyrimidinase-like 4
EFNB3 ephrin-B3
EPHX2 epoxide hydrolase 2, cytoplasmic
FAM76A family with sequence similarity 76, member A
FOS FBJ murine osteosarcoma viral oncogene homolog
FRMPD1 FERM and PDZ domain containing 1
GPR85 G protein-coupled receptor 85
HCG4 HLA complex group 4 (non-protein coding)
HDLBP high density lipoprotein binding protein
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HNF1B HNF1 homeobox B
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
ISG20 interferon stimulated exonuclease gene 20kDa
KCNIP1 Kv channel interacting protein 1
LARP7 La ribonucleoprotein domain family, member 7
LHX2 LIM homeobox 2
LMO7 LIM domain 7
LOC100131532 uncharacterized LOC100131532
LOC157562 uncharacterized LOC157562
MAGEB2 melanoma antigen family B2
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MARK4 MAP/microtubule affinity-regulating kinase 4
MOBP myelin-associated oligodendrocyte basic protein
MON2 MON2 homolog (S. cerevisiae)
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MVD mevalonate (diphospho) decarboxylase
MYCNOS MYCN opposite strand
MYH14 myosin, heavy chain 14, non-muscle
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NOX1 NADPH oxidase 1
NRSN2 neurensin 2
OAZ3 ornithine decarboxylase antizyme 3
OLFML2A olfactomedin-like 2A
PCDH12 protocadherin 12
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PITX2 paired-like homeodomain 2
POMT2 protein-O-mannosyltransferase 2
PRND prion protein 2 (dublet)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRB protein tyrosine phosphatase, receptor type, B
RBP4 retinol binding protein 4, plasma
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SATB2 SATB homeobox 2
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC43A3 solute carrier family 43, member 3
SNCAIP synuclein, alpha interacting protein
SOX10 SRY (sex determining region Y)-box 10
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SQSTM1 sequestosome 1
SSTR5 somatostatin receptor 5
SYNJ2 synaptojanin 2
TBX5 T-box 5
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TFEB transcription factor EB
TGM2 transglutaminase 2
TLE4 transducin-like enhancer of split 4
TMEM209 transmembrane protein 209
TNPO2 transportin 2
TRAK1 trafficking protein, kinesin binding 1
TRPA1 transient receptor potential cation channel, subfamily A, member 1
VAC14 Vac14 homolog (S. cerevisiae)
VIPR1 vasoactive intestinal peptide receptor 1
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF551 zinc finger protein 551
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
AHDC1 AT hook, DNA binding motif, containing 1
ARMC4 armadillo repeat containing 4
ARRB1 arrestin, beta 1
ASB7 ankyrin repeat and SOCS box containing 7
ATF3 activating transcription factor 3
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BCOR BCL6 corepressor
C19ORF40 chromosome 19 open reading frame 40
C1ORF159 chromosome 1 open reading frame 159
C8ORF60 chromosome 8 open reading frame 60
CARD8 caspase recruitment domain family, member 8
CCDC15 coiled-coil domain containing 15
CFD complement factor D (adipsin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCN5 chloride channel, voltage-sensitive 5
COG4 component of oligomeric golgi complex 4
CORO2A coronin, actin binding protein, 2A
CRY2 cryptochrome circadian clock 2
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EPPK1 epiplakin 1
ERO1L ERO1-like (S. cerevisiae)
FGD1 FYVE, RhoGEF and PH domain containing 1
FLT4 fms-related tyrosine kinase 4
GAN gigaxonin
GAREM GRB2 associated, regulator of MAPK1
GMPR guanosine monophosphate reductase
GPR19 G protein-coupled receptor 19
GPX2 glutathione peroxidase 2
GRB7 growth factor receptor-bound protein 7
GRPR gastrin-releasing peptide receptor
GSTA4 glutathione S-transferase alpha 4
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HOOK1 hook microtubule-tethering protein 1
IFT81 intraflagellar transport 81
IL15RA interleukin 15 receptor, alpha
IRAK4 interleukin-1 receptor-associated kinase 4
KCNK15 potassium channel, two pore domain subfamily K, member 15
KLC2 kinesin light chain 2
KRI1 KRI1 homolog (S. cerevisiae)
LOC100287590 uncharacterized LOC100287590
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LYRM9 LYR motif containing 9
MAGEF1 melanoma antigen family F1
MCOLN3 mucolipin 3
MMP9 matrix metallopeptidase 9
MTMR6 myotubularin related protein 6
MUC3A mucin 3A, cell surface associated
MXD3 MAX dimerization protein 3
NEK11 NIMA-related kinase 11
NFE2L3 nuclear factor, erythroid 2-like 3
NKX3-2 NK3 homeobox 2
NPIPB3 nuclear pore complex interacting protein family, member B3
NPY5R neuropeptide Y receptor Y5
NR1H2 nuclear receptor subfamily 1, group H, member 2
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGPEP1 pyroglutamyl-peptidase I
PLA2G3 phospholipase A2, group III
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PYCRL pyrroline-5-carboxylate reductase-like
R3HCC1L R3H domain and coiled-coil containing 1-like
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RPS17P5 ribosomal protein S17 pseudogene 5
SH2D4A SH2 domain containing 4A
SIRT6 sirtuin 6
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNHG3 small nucleolar RNA host gene 3
SULT4A1 sulfotransferase family 4A, member 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM104 transmembrane protein 104
TNS2 tensin 2
TPCN1 two pore segment channel 1
TRMT61A tRNA methyltransferase 61A
TUBA4A tubulin, alpha 4a
VGF VGF nerve growth factor inducible
WDR4 WD repeat domain 4
WWC2 WW and C2 domain containing 2
ZBTB22 zinc finger and BTB domain containing 22
ZBTB3 zinc finger and BTB domain containing 3
ZNF134 zinc finger protein 134
ZNF180 zinc finger protein 180
ZNF253 zinc finger protein 253
ZNF329 zinc finger protein 329
ZNF492 zinc finger protein 492
ZNF816 zinc finger protein 816