| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the erythromycin-2010 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADCY9 | adenylate cyclase 9 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C22ORF24 | chromosome 22 open reading frame 24 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CCDC176 | coiled-coil domain containing 176 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CHKA | choline kinase alpha |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CMTR1 | cap methyltransferase 1 |
| CYB561 | cytochrome b561 |
| DBF4 | DBF4 zinc finger |
| DUSP13 | dual specificity phosphatase 13 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| E2F1 | E2F transcription factor 1 |
| EHD1 | EH-domain containing 1 |
| ERCC8 | excision repair cross-complementation group 8 |
| FASTK | Fas-activated serine/threonine kinase |
| FBXO21 | F-box protein 21 |
| FBXO42 | F-box protein 42 |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| GLRX3 | glutaredoxin 3 |
| GMEB2 | glucocorticoid modulatory element binding protein 2 |
| GPX2 | glutathione peroxidase 2 |
| HIST1H4J | histone cluster 1, H4j |
| ICAM2 | intercellular adhesion molecule 2 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IDS | iduronate 2-sulfatase |
| INSIG2 | insulin induced gene 2 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| KIZ | kizuna centrosomal protein |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LAMA4 | laminin, alpha 4 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LETM1 | leucine zipper-EF-hand containing transmembrane protein 1 |
| LHFP | lipoma HMGIC fusion partner |
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 |
| MED27 | mediator complex subunit 27 |
| MED9 | mediator complex subunit 9 |
| METTL7A | methyltransferase like 7A |
| MIP | major intrinsic protein of lens fiber |
| MOB3B | MOB kinase activator 3B |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| NELL2 | NEL-like 2 (chicken) |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PENK | proenkephalin |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PRDX2 | peroxiredoxin 2 |
| RAB4B | RAB4B, member RAS oncogene family |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 |
| SMAD5 | SMAD family member 5 |
| SMAD6 | SMAD family member 6 |
| SOCS5 | suppressor of cytokine signaling 5 |
| STAP2 | signal transducing adaptor family member 2 |
| TMEM161A | transmembrane protein 161A |
| TMEM74B | transmembrane protein 74B |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TOM1 | target of myb1 (chicken) |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRD | T cell receptor delta locus |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| TUFT1 | tuftelin 1 |
| TWF1 | twinfilin actin binding protein 1 |
| UBL3 | ubiquitin-like 3 |
| UBTF | upstream binding transcription factor, RNA polymerase I |
| WRN | Werner syndrome, RecQ helicase-like |
| YIPF2 | Yip1 domain family, member 2 |
| ZNF175 | zinc finger protein 175 |
| ZNF224 | zinc finger protein 224 |
| ZNF408 | zinc finger protein 408 |
| ZNF473 | zinc finger protein 473 |
| ZNF500 | zinc finger protein 500 |
| ZNF721 | zinc finger protein 721 |
| Symbol | Name |
|---|---|
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| AIDA | axin interactor, dorsalization associated |
| ANKRD40 | ankyrin repeat domain 40 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| AUNIP | aurora kinase A and ninein interacting protein |
| BCORL1 | BCL6 corepressor-like 1 |
| BLMH | bleomycin hydrolase |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD151 | CD151 molecule (Raph blood group) |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEP72 | centrosomal protein 72kDa |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| COMMD8 | COMM domain containing 8 |
| CPOX | coproporphyrinogen oxidase |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa |
| DENND1A | DENN/MADD domain containing 1A |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DPY19L4 | dpy-19-like 4 (C. elegans) |
| EDAR | ectodysplasin A receptor |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FUBP3 | far upstream element (FUSE) binding protein 3 |
| GALNS | galactosamine (N-acetyl)-6-sulfatase |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST2H2BE | histone cluster 2, H2be |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HSD17B4 | hydroxysteroid (17-beta) dehydrogenase 4 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KCTD5 | potassium channel tetramerization domain containing 5 |
| KIAA0894 | KIAA0894 protein |
| KIFAP3 | kinesin-associated protein 3 |
| KPTN | kaptin (actin binding protein) |
| LACTB2 | lactamase, beta 2 |
| LOC440434 | aminopeptidase puromycin sensitive pseudogene |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAGT1 | magnesium transporter 1 |
| MEAF6 | MYST/Esa1-associated factor 6 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MGAM | maltase-glucoamylase |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MSRA | methionine sulfoxide reductase A |
| MTERF1 | mitochondrial transcription termination factor 1 |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDE1 | nudE neurodevelopment protein 1 |
| NEK11 | NIMA-related kinase 11 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| PAQR3 | progestin and adipoQ receptor family member III |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PEX12 | peroxisomal biogenesis factor 12 |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RAB5B | RAB5B, member RAS oncogene family |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RNASE6 | ribonuclease, RNase A family, k6 |
| RNF146 | ring finger protein 146 |
| RNMTL1 | RNA methyltransferase like 1 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SMAD7 | SMAD family member 7 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SPON2 | spondin 2, extracellular matrix protein |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| SPX | spexin hormone |
| SRBD1 | S1 RNA binding domain 1 |
| SYNGR2 | synaptogyrin 2 |
| TCTN2 | tectonic family member 2 |
| TFB2M | transcription factor B2, mitochondrial |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM243 | transmembrane protein 243, mitochondrial |
| TOB1 | transducer of ERBB2, 1 |
| TRIM8 | tripartite motif containing 8 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TSLIG2 | tRNA splicing ligase complex subunit 2 |
| TSPAN14 | tetraspanin 14 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| WDR43 | WD repeat domain 43 |
| ZNF32 | zinc finger protein 32 |