erythromycin-5329 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the erythromycin-5329 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHI1 Abelson helper integration site 1
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APC adenomatous polyposis coli
APOC1 apolipoprotein C-I
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARTN artemin
ATP11A ATPase, class VI, type 11A
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
CAPN15 calpain 15
CASKIN2 CASK interacting protein 2
CCDC69 coiled-coil domain containing 69
CDK13 cyclin-dependent kinase 13
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHKA choline kinase alpha
CHKB choline kinase beta
CPTP ceramide-1-phosphate transfer protein
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTNNBL1 catenin, beta like 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DIEXF digestive organ expansion factor homolog (zebrafish)
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF3A eukaryotic translation initiation factor 3, subunit A
FGFR1 fibroblast growth factor receptor 1
GLUD2 glutamate dehydrogenase 2
GUSBP3 glucuronidase, beta pseudogene 3
HABP4 hyaluronan binding protein 4
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HDAC11 histone deacetylase 11
HOXC8 homeobox C8
HPS1 Hermansky-Pudlak syndrome 1
HR hair growth associated
IFITM1 interferon induced transmembrane protein 1
IFT54 intraflagellar transport 54
IGFBP3 insulin-like growth factor binding protein 3
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCTD13 potassium channel tetramerization domain containing 13
LAMC2 laminin, gamma 2
LARP7 La ribonucleoprotein domain family, member 7
LZTR1 leucine-zipper-like transcription regulator 1
MAP4 microtubule-associated protein 4
MAPT microtubule-associated protein tau
MAST3 microtubule associated serine/threonine kinase 3
MCF2L MCF.2 cell line derived transforming sequence-like
MED14 mediator complex subunit 14
MZF1 myeloid zinc finger 1
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NEK1 NIMA-related kinase 1
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFIB nuclear factor I/B
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFYA nuclear transcription factor Y, alpha
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NR2C1 nuclear receptor subfamily 2, group C, member 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRG2 neuregulin 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PCSK6 proprotein convertase subtilisin/kexin type 6
PDLIM7 PDZ and LIM domain 7 (enigma)
PIAS2 protein inhibitor of activated STAT, 2
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
POFUT1 protein O-fucosyltransferase 1
POT1 protection of telomeres 1
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
RAB6A RAB6A, member RAS oncogene family
RAD51B RAD51 paralog B
RANBP3 RAN binding protein 3
RSL1D1 ribosomal L1 domain containing 1
RTEL1 regulator of telomere elongation helicase 1
SCGB2A2 secretoglobin, family 2A, member 2
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKA1 spindle and kinetochore associated complex subunit 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNTA1 syntrophin, alpha 1
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAPBP TAP binding protein (tapasin)
TAZ tafazzin
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TMEM63A transmembrane protein 63A
TMEM80 transmembrane protein 80
TRIO trio Rho guanine nucleotide exchange factor
TXNL4A thioredoxin-like 4A
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZBTB25 zinc finger and BTB domain containing 25
ZNF551 zinc finger protein 551

decreased expression

Symbol Name
ACYP2 acylphosphatase 2, muscle type
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANXA2P3 annexin A2 pseudogene 3
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ASAP1-IT1 ASAP1 intronic transcript 1
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD5 ATPase family, AAA domain containing 5
ATG14 autophagy related 14
BAHD1 bromo adjacent homology domain containing 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCORL1 BCL6 corepressor-like 1
C14ORF132 chromosome 14 open reading frame 132
C1ORF159 chromosome 1 open reading frame 159
CAMKMT calmodulin-lysine N-methyltransferase
CAPG capping protein (actin filament), gelsolin-like
CCDC121 coiled-coil domain containing 121
CCDC94 coiled-coil domain containing 94
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP97 centrosomal protein 97kDa
CHRM3 cholinergic receptor, muscarinic 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL4A5 collagen, type IV, alpha 5
COQ6 coenzyme Q6 monooxygenase
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ENO2 enolase 2 (gamma, neuronal)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERI3 ERI1 exoribonuclease family member 3
EVPL envoplakin
FA2H fatty acid 2-hydroxylase
FAM222B family with sequence similarity 222, member B
FAM53B family with sequence similarity 53, member B
FBXW12 F-box and WD repeat domain containing 12
GLS2 glutaminase 2 (liver, mitochondrial)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HSPA2 heat shock 70kDa protein 2
IREB2 iron-responsive element binding protein 2
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KDM5C lysine (K)-specific demethylase 5C
LMNB1 lamin B1
LOC730101 uncharacterized LOC730101
MEFV Mediterranean fever
MGC12488
MPI mannose phosphate isomerase
MVD mevalonate (diphospho) decarboxylase
MVP major vault protein
MYO1E myosin IE
NDE1 nudE neurodevelopment protein 1
NPM3 nucleophosmin/nucleoplasmin 3
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHA9 protocadherin alpha 9
PCSK7 proprotein convertase subtilisin/kexin type 7
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PLXNA3 plexin A3
PMM1 phosphomannomutase 1
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RAB33B RAB33B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RFTN1 raftlin, lipid raft linker 1
RIBC2 RIB43A domain with coiled-coils 2
RIPK4 receptor-interacting serine-threonine kinase 4
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF126P1 ring finger protein 126 pseudogene 1
RPH3AL rabphilin 3A-like (without C2 domains)
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAMP3 secretory carrier membrane protein 3
SCAMP5 secretory carrier membrane protein 5
SCD5 stearoyl-CoA desaturase 5
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SIRT6 sirtuin 6
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SNX15 sorting nexin 15
SOWAHC sosondowah ankyrin repeat domain family member C
SYCP2 synaptonemal complex protein 2
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TCTN2 tectonic family member 2
TNS2 tensin 2
TPCN1 two pore segment channel 1
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSPYL2 TSPY-like 2
TUBA3C tubulin, alpha 3c
VAV1 vav 1 guanine nucleotide exchange factor
VEGFC vascular endothelial growth factor C
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WDR91 WD repeat domain 91
XK X-linked Kx blood group
ZBTB39 zinc finger and BTB domain containing 39
ZFP69B ZFP69 zinc finger protein B
ZMAT5 zinc finger, matrin-type 5
ZNF219 zinc finger protein 219
ZNF324 zinc finger protein 324