| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the erythromycin-6729 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| APC2 | adenomatosis polyposis coli 2 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| CCDC28B | coiled-coil domain containing 28B |
| CCDC71 | coiled-coil domain containing 71 |
| CD82 | CD82 molecule |
| CDC14A | cell division cycle 14A |
| CDC42 | cell division cycle 42 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CLDN18 | claudin 18 |
| CLSPN | claspin |
| CRHR1 | corticotropin releasing hormone receptor 1 |
| CST5 | cystatin D |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CWH43 | cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) |
| DLC1 | DLC1 Rho GTPase activating protein |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| DTNB | dystrobrevin, beta |
| DUSP9 | dual specificity phosphatase 9 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 |
| EFNB1 | ephrin-B1 |
| ELK1 | ELK1, member of ETS oncogene family |
| EPS8L1 | EPS8-like 1 |
| FBLN1 | fibulin 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GGT1 | gamma-glutamyltransferase 1 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GPR21 | G protein-coupled receptor 21 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| HAP1 | huntingtin-associated protein 1 |
| HHLA1 | HERV-H LTR-associating 1 |
| HIP1 | huntingtin interacting protein 1 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HIST1H3I | histone cluster 1, H3i |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IL11 | interleukin 11 |
| ITGB6 | integrin, beta 6 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KCNJ13 | potassium channel, inwardly rectifying subfamily J, member 13 |
| KIAA1467 | KIAA1467 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog |
| KRT38 | keratin 38, type I |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LYZ | lysozyme |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MNMIP1 | manchette microtubule inner protein 1 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MS4A5 | membrane-spanning 4-domains, subfamily A, member 5 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
| NEK9 | NIMA-related kinase 9 |
| NNMT | nicotinamide N-methyltransferase |
| NRAP | nebulin-related anchoring protein |
| NXPH4 | neurexophilin 4 |
| OMD | osteomodulin |
| PALM | paralemmin |
| PASK | PAS domain containing serine/threonine kinase |
| PCDHB13 | protocadherin beta 13 |
| PCDHGA11 | protocadherin gamma subfamily A, 11 |
| PCDHGB6 | protocadherin gamma subfamily B, 6 |
| PGAM2 | phosphoglycerate mutase 2 (muscle) |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| POU5F1B | POU class 5 homeobox 1B |
| POU6F1 | POU class 6 homeobox 1 |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 |
| PTGDR2 | prostaglandin D2 receptor 2 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 |
| ROR2 | receptor tyrosine kinase-like orphan receptor 2 |
| RUNDC3A | RUN domain containing 3A |
| RUNX1 | runt-related transcription factor 1 |
| SCRT1 | scratch family zinc finger 1 |
| SGSM3 | small G protein signaling modulator 3 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SOCS3 | suppressor of cytokine signaling 3 |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
| TBXA2R | thromboxane A2 receptor |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TLR1 | toll-like receptor 1 |
| TNNT3 | troponin T type 3 (skeletal, fast) |
| TRH | thyrotropin-releasing hormone |
| TRIM29 | tripartite motif containing 29 |
| TRPC3 | transient receptor potential cation channel, subfamily C, member 3 |
| TSPAN2 | tetraspanin 2 |
| VAX2 | ventral anterior homeobox 2 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF154 | zinc finger protein 154 |
| ZNF609 | zinc finger protein 609 |
| ZNF688 | zinc finger protein 688 |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACE | angiotensin I converting enzyme |
| ACKR3 | atypical chemokine receptor 3 |
| AFAP1 | actin filament associated protein 1 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| APOC4 | apolipoprotein C-IV |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| AVPI1 | arginine vasopressin-induced 1 |
| AXIN1 | axin 1 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BOLA1 | bolA family member 1 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CASS4 | Cas scaffolding protein family member 4 |
| CCNA1 | cyclin A1 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CLDN15 | claudin 15 |
| CLIC3 | chloride intracellular channel 3 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNN1 | calponin 1, basic, smooth muscle |
| CPZ | carboxypeptidase Z |
| DAGLA | diacylglycerol lipase, alpha |
| DCSTAMP | dendrocyte expressed seven transmembrane protein |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DMTN | dematin actin binding protein |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FRAT1 | frequently rearranged in advanced T-cell lymphomas 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HESX1 | HESX homeobox 1 |
| HIRA | histone cell cycle regulator |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3B | histone cluster 1, H3b |
| HMHA1 | histocompatibility (minor) HA-1 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IQCG | IQ motif containing G |
| JUNB | jun B proto-oncogene |
| KIAA1107 | KIAA1107 |
| KIRREL | kin of IRRE like (Drosophila) |
| LIFR | leukemia inhibitory factor receptor alpha |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LRRC6 | leucine rich repeat containing 6 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MUC3B | mucin 3B, cell surface associated |
| MXD3 | MAX dimerization protein 3 |
| MYO1F | myosin IF |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OSBP2 | oxysterol binding protein 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PALMD | palmdelphin |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PTK6 | protein tyrosine kinase 6 |
| QSER1 | glutamine and serine rich 1 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RNF25 | ring finger protein 25 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RWDD2A | RWD domain containing 2A |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNTG1 | syntrophin, gamma 1 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| TAGLN3 | transgelin 3 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TUBA4B | tubulin, alpha 4b |
| WDR25 | WD repeat domain 25 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| YY2 | YY2 transcription factor |
| ZNF215 | zinc finger protein 215 |
| ZNF253 | zinc finger protein 253 |
| ZNF552 | zinc finger protein 552 |
| ZNF668 | zinc finger protein 668 |
| ZNF711 | zinc finger protein 711 |