esculetin-3120 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

194 genes differentially expressed following the esculetin-3120 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ACACB acetyl-CoA carboxylase beta
ACAN aggrecan
ACVR1B activin A receptor, type IB
ADD2 adducin 2 (beta)
ADGRL1 adhesion G protein-coupled receptor L1
AKAP4 A kinase (PRKA) anchor protein 4
ANGPTL2 angiopoietin-like 2
ANKMY1 ankyrin repeat and MYND domain containing 1
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARHGAP33 Rho GTPase activating protein 33
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
B9D1 B9 protein domain 1
BCAS3 breast carcinoma amplified sequence 3
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CAMKMT calmodulin-lysine N-methyltransferase
CD2 CD2 molecule
CD47 CD47 molecule
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CENPT centromere protein T
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CYB5R2 cytochrome b5 reductase 2
DEPTOR DEP domain containing MTOR-interacting protein
EHD1 EH-domain containing 1
ENDOD1 endonuclease domain containing 1
EPHB2 EPH receptor B2
ERAP1 endoplasmic reticulum aminopeptidase 1
FABP3 fatty acid binding protein 3, muscle and heart
FASLG Fas ligand (TNF superfamily, member 6)
FBXL18 F-box and leucine-rich repeat protein 18
FLOT1 flotillin 1
FOXG1 forkhead box G1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GID4 GID complex subunit 4
GPR153 G protein-coupled receptor 153
GTDC1 glycosyltransferase-like domain containing 1
HHLA1 HERV-H LTR-associating 1
HIST1H4E histone cluster 1, H4e
HOXA1 homeobox A1
HOXA4 homeobox A4
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
ICA1 islet cell autoantigen 1, 69kDa
ICAM1 intercellular adhesion molecule 1
IDS iduronate 2-sulfatase
IL16 interleukin 16
IL36G interleukin 36, gamma
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KRT86 keratin 86, type II
LHFPL2 lipoma HMGIC fusion partner-like 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LRRN3 leucine rich repeat neuronal 3
MAP4 microtubule-associated protein 4
MFSD6 major facilitator superfamily domain containing 6
MMP1 matrix metallopeptidase 1
MOB3B MOB kinase activator 3B
MPZL1 myelin protein zero-like 1
MTMR10 myotubularin related protein 10
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NMT2 N-myristoyltransferase 2
NPTX1 neuronal pentraxin I
OMG oligodendrocyte myelin glycoprotein
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
PLCD1 phospholipase C, delta 1
POU3F4 POU class 3 homeobox 4
PPARD peroxisome proliferator-activated receptor delta
PROSC proline synthetase co-transcribed homolog (bacterial)
PSG9 pregnancy specific beta-1-glycoprotein 9
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RECQL5 RecQ protein-like 5
RGSL1 regulator of G-protein signaling like 1
SAFB scaffold attachment factor B
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SRR serine racemase
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
SYCP2 synaptonemal complex protein 2
TGFB1 transforming growth factor, beta 1
TMCC2 transmembrane and coiled-coil domain family 2
TRIM3 tripartite motif containing 3
ULBP2 UL16 binding protein 2
ULK4 unc-51 like kinase 4
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
YPEL1 yippee-like 1 (Drosophila)
ZER1 zyg-11 related, cell cycle regulator
ZNF287 zinc finger protein 287
ZNF324 zinc finger protein 324
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACOX2 acyl-CoA oxidase 2, branched chain
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AXIN1 axin 1
B3GNT1
BAHCC1 BAH domain and coiled-coil containing 1
C14ORF93 chromosome 14 open reading frame 93
CBR3 carbonyl reductase 3
CCNT1 cyclin T1
CDCP1 CUB domain containing protein 1
CDKL3 cyclin-dependent kinase-like 3
CNTLN centlein, centrosomal protein
CORT cortistatin
CPTP ceramide-1-phosphate transfer protein
CXCL2 chemokine (C-X-C motif) ligand 2
DCAF13 DDB1 and CUL4 associated factor 13
DGKE diacylglycerol kinase, epsilon 64kDa
DOLK dolichol kinase
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ELMO3 engulfment and cell motility 3
ENO3 enolase 3 (beta, muscle)
EXOC6B exocyst complex component 6B
FHIT fragile histidine triad
FLJ21369 uncharacterized protein FLJ21369
GAMT guanidinoacetate N-methyltransferase
GJA1 gap junction protein, alpha 1, 43kDa
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR19 G protein-coupled receptor 19
GPR3 G protein-coupled receptor 3
GRIP2 glutamate receptor interacting protein 2
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H1T histone cluster 1, H1t
HIST1H2BI histone cluster 1, H2bi
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
HIST1H3G histone cluster 1, H3g
HIST1H4C histone cluster 1, H4c
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGLV1-44 immunoglobulin lambda variable 1-44
IL12B interleukin 12B
INO80D INO80 complex subunit D
IQSEC2 IQ motif and Sec7 domain 2
JMJD4 jumonji domain containing 4
KLF13 Kruppel-like factor 13
KLHL28 kelch-like family member 28
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LRRC6 leucine rich repeat containing 6
LTBP3 latent transforming growth factor beta binding protein 3
MRPL24 mitochondrial ribosomal protein L24
NAG18 NAG18 mRNA
NCS1 neuronal calcium sensor 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NTHL1 nth endonuclease III-like 1 (E. coli)
PCDHGB5 protocadherin gamma subfamily B, 5
PIP prolactin-induced protein
PLCB4 phospholipase C, beta 4
PLCL1 phospholipase C-like 1
PLK1 polo-like kinase 1
PRKCZ protein kinase C, zeta
PSKH1 protein serine kinase H1
PTDSS2 phosphatidylserine synthase 2
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAB3D RAB3D, member RAS oncogene family
RANBP17 RAN binding protein 17
RAP1GAP2 RAP1 GTPase activating protein 2
RCAN3 RCAN family member 3
RNF126P1 ring finger protein 126 pseudogene 1
SALL2 spalt-like transcription factor 2
SCARB1 scavenger receptor class B, member 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SIK1 salt-inducible kinase 1
SMR3A submaxillary gland androgen regulated protein 3A
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
TAS2R4 taste receptor, type 2, member 4
TIAM2 T-cell lymphoma invasion and metastasis 2
TIGD6 tigger transposable element derived 6
TRAF1 TNF receptor-associated factor 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPAN32 tetraspanin 32
UNC93B1 unc-93 homolog B1 (C. elegans)
UPK3A uroplakin 3A
WNT16 wingless-type MMTV integration site family, member 16
ZDHHC24 zinc finger, DHHC-type containing 24
ZFHX3 zinc finger homeobox 3
ZHX2 zinc fingers and homeoboxes 2
ZMAT5 zinc finger, matrin-type 5
ZNF234 zinc finger protein 234
ZNF408 zinc finger protein 408
ZNF492 zinc finger protein 492
ZNF862 zinc finger protein 862