| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the esculetin-7459 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADAM20 | ADAM metallopeptidase domain 20 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADRA1D | adrenoceptor alpha 1D |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ARMC4 | armadillo repeat containing 4 |
| ART1 | ADP-ribosyltransferase 1 |
| ATP10B | ATPase, class V, type 10B |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| C1ORF61 | chromosome 1 open reading frame 61 |
| CALB2 | calbindin 2 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CSPP1 | centrosome and spindle pole associated protein 1 |
| CTAGE5 | CTAGE family, member 5 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CYBB | cytochrome b-245, beta polypeptide |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| ECE1 | endothelin converting enzyme 1 |
| ERCC2 | excision repair cross-complementation group 2 |
| EWSR1 | EWS RNA-binding protein 1 |
| FADS3 | fatty acid desaturase 3 |
| FLJ42627 | uncharacterized LOC645644 |
| FOXG1 | forkhead box G1 |
| GLI1 | GLI family zinc finger 1 |
| GPR137 | G protein-coupled receptor 137 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GSTM4 | glutathione S-transferase mu 4 |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HFE | hemochromatosis |
| HIST1H1B | histone cluster 1, H1b |
| HPX | hemopexin |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| IRS2 | insulin receptor substrate 2 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KHSRP | KH-type splicing regulatory protein |
| LAT2 | linker for activation of T cells family, member 2 |
| LHX2 | LIM homeobox 2 |
| LMAN1 | lectin, mannose-binding, 1 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP4 | microtubule-associated protein 4 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MYL5 | myosin, light chain 5, regulatory |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NCOR2 | nuclear receptor corepressor 2 |
| NF2 | neurofibromin 2 (merlin) |
| NOP14-AS1 | NOP14 antisense RNA 1 |
| PAX2 | paired box 2 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLAC1 | placenta-specific 1 |
| PLCD1 | phospholipase C, delta 1 |
| POLL | polymerase (DNA directed), lambda |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| PTH1R | parathyroid hormone 1 receptor |
| RAB33A | RAB33A, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase |
| RPL18 | ribosomal protein L18 |
| RPL35A | ribosomal protein L35a |
| S100A8 | S100 calcium binding protein A8 |
| SAPCD1 | suppressor APC domain containing 1 |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPN | sialophorin |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| STAB2 | stabilin 2 |
| STIM1 | stromal interaction molecule 1 |
| STK11 | serine/threonine kinase 11 |
| SYNJ2 | synaptojanin 2 |
| THBS3 | thrombospondin 3 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEM97 | transmembrane protein 97 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| USP34 | ubiquitin specific peptidase 34 |
| WIZ | widely interspaced zinc finger motifs |
| WNT2B | wingless-type MMTV integration site family, member 2B |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| Symbol | Name |
|---|---|
| AEN | apoptosis enhancing nuclease |
| AGO3 | argonaute RISC catalytic component 3 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ANKRD36 | ankyrin repeat domain 36 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ANXA1 | annexin A1 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARMC7 | armadillo repeat containing 7 |
| ASRGL1 | asparaginase like 1 |
| AXIN1 | axin 1 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCNL2 | cyclin L2 |
| CD82 | CD82 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CIC | capicua transcriptional repressor |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAL4 | dynein, axonemal, light chain 4 |
| EFHC1 | EF-hand domain (C-terminal) containing 1 |
| EPHA2 | EPH receptor A2 |
| FBXO31 | F-box protein 31 |
| FCHO1 | FCH domain only 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GALK1 | galactokinase 1 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPX2 | glutathione peroxidase 2 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H4F | histone cluster 1, H4f |
| HS1BP3 | HCLS1 binding protein 3 |
| IL4R | interleukin 4 receptor |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IRF6 | interferon regulatory factor 6 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| KLHDC4 | kelch domain containing 4 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAPK12 | mitogen-activated protein kinase 12 |
| MGC12488 | |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MPI | mannose phosphate isomerase |
| MPST | mercaptopyruvate sulfurtransferase |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MTRF1 | mitochondrial translational release factor 1 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PGP | phosphoglycolate phosphatase |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PIGT | phosphatidylinositol glycan anchor biosynthesis, class T |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLA2G15 | phospholipase A2, group XV |
| PLD2 | phospholipase D2 |
| PMM1 | phosphomannomutase 1 |
| PODXL2 | podocalyxin-like 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RGS19 | regulator of G-protein signaling 19 |
| RNF2 | ring finger protein 2 |
| RNF25 | ring finger protein 25 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RRP1 | ribosomal RNA processing 1 |
| SETD3 | SET domain containing 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBC1D17 | TBC1 domain family, member 17 |
| TEAD3 | TEA domain family member 3 |
| TMEM104 | transmembrane protein 104 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TUBA3C | tubulin, alpha 3c |
| UBXN6 | UBX domain protein 6 |
| VEGFC | vascular endothelial growth factor C |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZNF248 | zinc finger protein 248 |
| ZNF8 | zinc finger protein 8 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
