| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the esculin-3052 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD6 | abhydrolase domain containing 6 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ADAM28 | ADAM metallopeptidase domain 28 |
| ALPL | alkaline phosphatase, liver/bone/kidney |
| AMBP | alpha-1-microglobulin/bikunin precursor |
| ANGPT2 | angiopoietin 2 |
| ANGPTL2 | angiopoietin-like 2 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
| ARHGAP26 | Rho GTPase activating protein 26 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BGN | biglycan |
| BMP15 | bone morphogenetic protein 15 |
| C10ORF12 | chromosome 10 open reading frame 12 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CD248 | CD248 molecule, endosialin |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLIC2 | chloride intracellular channel 2 |
| COL10A1 | collagen, type X, alpha 1 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| COPE | coatomer protein complex, subunit epsilon |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CUEDC1 | CUE domain containing 1 |
| DDX4 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EHD2 | EH-domain containing 2 |
| ELN | elastin |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FMO1 | flavin containing monooxygenase 1 |
| FOXO1 | forkhead box O1 |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GNAS | GNAS complex locus |
| GRHL2 | grainyhead-like 2 (Drosophila) |
| HEMK1 | HemK methyltransferase family member 1 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HR | hair growth associated |
| HRASLS2 | HRAS-like suppressor 2 |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| IL36RN | interleukin 36 receptor antagonist |
| KAT8 | K(lysine) acetyltransferase 8 |
| KCNMB2 | potassium channel subfamily M regulatory beta subunit 2 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KNG1 | kininogen 1 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOC57399 | uncharacterized gastric protein ZA52P |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MDK | midkine (neurite growth-promoting factor 2) |
| MEIS3P1 | Meis homeobox 3 pseudogene 1 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MYOZ2 | myozenin 2 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NEUROG2 | neurogenin 2 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| NRP1 | neuropilin 1 |
| NTM | neurotrimin |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RNF186 | ring finger protein 186 |
| ROM1 | retinal outer segment membrane protein 1 |
| RRBP1 | ribosome binding protein 1 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLCO1A2 | solute carrier organic anion transporter family, member 1A2 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| STEAP4 | STEAP family member 4 |
| STX11 | syntaxin 11 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TACR1 | tachykinin receptor 1 |
| TBX5 | T-box 5 |
| TMOD1 | tropomodulin 1 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNP2 | transition protein 2 (during histone to protamine replacement) |
| UPK2 | uroplakin 2 |
| VSIG10 | V-set and immunoglobulin domain containing 10 |
| WTAP | Wilms tumor 1 associated protein |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF235 | zinc finger protein 235 |
| ZNF276 | zinc finger protein 276 |
| ZNF287 | zinc finger protein 287 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| ALDOAP2 | aldolase A, fructose-bisphosphate pseudogene 2 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| AXIN1 | axin 1 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C8A | complement component 8, alpha polypeptide |
| C9ORF3 | chromosome 9 open reading frame 3 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CARF | calcium responsive transcription factor |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD300C | CD300c molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CELP | carboxyl ester lipase pseudogene |
| CFAP69 | cilia and flagella associated protein 69 |
| COQ6 | coenzyme Q6 monooxygenase |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DSPP | dentin sialophosphoprotein |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM50B | family with sequence similarity 50, member B |
| FBXO46 | F-box protein 46 |
| FGF23 | fibroblast growth factor 23 |
| FOXD1 | forkhead box D1 |
| FOXN2 | forkhead box N2 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FPGS | folylpolyglutamate synthase |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GPC3 | glypican 3 |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AG | histone cluster 1, H2ag |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3G | histone cluster 1, H3g |
| HOXB9 | homeobox B9 |
| IBSP | integrin-binding sialoprotein |
| IL18 | interleukin 18 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIAA1456 | KIAA1456 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LRRC20 | leucine rich repeat containing 20 |
| METTL21B | methyltransferase like 21B |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MYO15A | myosin XVA |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PKN1 | protein kinase N1 |
| PLTP | phospholipid transfer protein |
| POMZP3 | POM121 and ZP3 fusion |
| PRSS53 | protease, serine, 53 |
| RAB17 | RAB17, member RAS oncogene family |
| RAB3D | RAB3D, member RAS oncogene family |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RUSC2 | RUN and SH3 domain containing 2 |
| SALL2 | spalt-like transcription factor 2 |
| SGMS1 | sphingomyelin synthase 1 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC35F5 | solute carrier family 35, member F5 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| TAGLN | transgelin |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TBKBP1 | TBK1 binding protein 1 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TMEM212 | transmembrane protein 212 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA3D | tubulin, alpha 3d |
| UPB1 | ureidopropionase, beta |
| UPK3A | uroplakin 3A |
| WASF3 | WAS protein family, member 3 |
| YOD1 | YOD1 deubiquitinase |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF10 | zinc finger protein 10 |
