| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the esculin-3390 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| AP2S1 | adaptor-related protein complex 2, sigma 1 subunit |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BAIAP3 | BAI1-associated protein 3 |
| BARX2 | BARX homeobox 2 |
| BCAN | brevican |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BST2 | bone marrow stromal cell antigen 2 |
| C10ORF12 | chromosome 10 open reading frame 12 |
| C6ORF10 | chromosome 6 open reading frame 10 |
| CD6 | CD6 molecule |
| CEP112 | centrosomal protein 112kDa |
| CLTB | clathrin, light chain B |
| COL9A3 | collagen, type IX, alpha 3 |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CTAGE1 | cutaneous T-cell lymphoma-associated antigen 1 |
| CTNS | cystinosin, lysosomal cystine transporter |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| ELL | elongation factor RNA polymerase II |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FRMD1 | FERM domain containing 1 |
| FRMD4A | FERM domain containing 4A |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GCK | glucokinase (hexokinase 4) |
| GNAT1 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| HIST1H4C | histone cluster 1, H4c |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXD11 | homeobox D11 |
| IL36G | interleukin 36, gamma |
| ITIH3 | inter-alpha-trypsin inhibitor heavy chain 3 |
| JADE2 | jade family PHD finger 2 |
| KEL | Kell blood group, metallo-endopeptidase |
| KIAA0040 | KIAA0040 |
| KIF25-AS1 | KIF25 antisense RNA 1 |
| LENEP | lens epithelial protein |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MDFI | MyoD family inhibitor |
| MLXIPL | MLX interacting protein-like |
| MNMIP1 | manchette microtubule inner protein 1 |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MST1 | macrophage stimulating 1 |
| MUC3B | mucin 3B, cell surface associated |
| MZT2B | mitotic spindle organizing protein 2B |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| OGDHL | oxoglutarate dehydrogenase-like |
| OMG | oligodendrocyte myelin glycoprotein |
| PAX5 | paired box 5 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLAT | plasminogen activator, tissue |
| POU2F2 | POU class 2 homeobox 2 |
| PQLC2 | PQ loop repeat containing 2 |
| PTAFR | platelet-activating factor receptor |
| PTPRD | protein tyrosine phosphatase, receptor type, D |
| RGS12 | regulator of G-protein signaling 12 |
| RNF122 | ring finger protein 122 |
| RNF17 | ring finger protein 17 |
| RPL35A | ribosomal protein L35a |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SMR3B | submaxillary gland androgen regulated protein 3B |
| SNX1 | sorting nexin 1 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPRR1A | small proline-rich protein 1A |
| SPRR1B | small proline-rich protein 1B |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STAG3 | stromal antigen 3 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TAGLN3 | transgelin 3 |
| TBXA2R | thromboxane A2 receptor |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TPMT | thiopurine S-methyltransferase |
| TPSG1 | tryptase gamma 1 |
| TRD | T cell receptor delta locus |
| TRIB2 | tribbles pseudokinase 2 |
| TRIL | TLR4 interactor with leucine-rich repeats |
| TTC38 | tetratricopeptide repeat domain 38 |
| UNC5B | unc-5 homolog B (C. elegans) |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF646 | zinc finger protein 646 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AFAP1 | actin filament associated protein 1 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARSB | arylsulfatase B |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
| BCORL1 | BCL6 corepressor-like 1 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CALML5 | calmodulin-like 5 |
| CCNK | cyclin K |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CNTNAP1 | contactin associated protein 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DNM3 | dynamin 3 |
| ERCC5 | excision repair cross-complementation group 5 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO2 | F-box protein 2 |
| FER | fer (fps/fes related) tyrosine kinase |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FUZ | fuzzy planar cell polarity protein |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GMPR | guanosine monophosphate reductase |
| GPATCH4 | G patch domain containing 4 |
| HDAC11 | histone deacetylase 11 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BO | histone cluster 1, H2bo |
| HOXC8 | homeobox C8 |
| HPX | hemopexin |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| HYAL1 | hyaluronoglucosaminidase 1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL22 | interleukin 22 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KDM5C | lysine (K)-specific demethylase 5C |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAGEA5 | melanoma antigen family A5 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MITF | microphthalmia-associated transcription factor |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MST1R | macrophage stimulating 1 receptor |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NCALD | neurocalcin delta |
| NEUROD4 | neuronal differentiation 4 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PALM | paralemmin |
| PHF14 | PHD finger protein 14 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLCD1 | phospholipase C, delta 1 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RFPL1S | RFPL1 antisense RNA 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SECTM1 | secreted and transmembrane 1 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SNX15 | sorting nexin 15 |
| SP1 | Sp1 transcription factor |
| STK16 | serine/threonine kinase 16 |
| SYT17 | synaptotagmin XVII |
| TBKBP1 | TBK1 binding protein 1 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TH | tyrosine hydroxylase |
| TMEM254 | transmembrane protein 254 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TOM1 | target of myb1 (chicken) |
| TUBA3C | tubulin, alpha 3c |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| UPK2 | uroplakin 2 |
| UPP1 | uridine phosphorylase 1 |
| XYLT1 | xylosyltransferase I |
| ZNF227 | zinc finger protein 227 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF552 | zinc finger protein 552 |