esculin-3390 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the esculin-3390 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACSL5 acyl-CoA synthetase long-chain family member 5
AKAP6 A kinase (PRKA) anchor protein 6
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARHGAP26 Rho GTPase activating protein 26
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BAHCC1 BAH domain and coiled-coil containing 1
BAIAP3 BAI1-associated protein 3
BARX2 BARX homeobox 2
BCAN brevican
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BST2 bone marrow stromal cell antigen 2
C10ORF12 chromosome 10 open reading frame 12
C6ORF10 chromosome 6 open reading frame 10
CD6 CD6 molecule
CEP112 centrosomal protein 112kDa
CLTB clathrin, light chain B
COL9A3 collagen, type IX, alpha 3
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CRELD1 cysteine-rich with EGF-like domains 1
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
CTNS cystinosin, lysosomal cystine transporter
DIO2 deiodinase, iodothyronine, type II
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
ELL elongation factor RNA polymerase II
ELP6 elongator acetyltransferase complex subunit 6
ERO1LB ERO1-like beta (S. cerevisiae)
FRMD1 FERM domain containing 1
FRMD4A FERM domain containing 4A
FYN FYN proto-oncogene, Src family tyrosine kinase
GCK glucokinase (hexokinase 4)
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
GREB1L growth regulation by estrogen in breast cancer-like
HIST1H4C histone cluster 1, H4c
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXD11 homeobox D11
IL36G interleukin 36, gamma
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
JADE2 jade family PHD finger 2
KEL Kell blood group, metallo-endopeptidase
KIAA0040 KIAA0040
KIF25-AS1 KIF25 antisense RNA 1
LENEP lens epithelial protein
LINC00216 long intergenic non-protein coding RNA 216
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MDFI MyoD family inhibitor
MLXIPL MLX interacting protein-like
MNMIP1 manchette microtubule inner protein 1
MOBP myelin-associated oligodendrocyte basic protein
MRPL41 mitochondrial ribosomal protein L41
MST1 macrophage stimulating 1
MUC3B mucin 3B, cell surface associated
MZT2B mitotic spindle organizing protein 2B
N4BP2L1 NEDD4 binding protein 2-like 1
OGDHL oxoglutarate dehydrogenase-like
OMG oligodendrocyte myelin glycoprotein
PAX5 paired box 5
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAT plasminogen activator, tissue
POU2F2 POU class 2 homeobox 2
PQLC2 PQ loop repeat containing 2
PTAFR platelet-activating factor receptor
PTPRD protein tyrosine phosphatase, receptor type, D
RGS12 regulator of G-protein signaling 12
RNF122 ring finger protein 122
RNF17 ring finger protein 17
RPL35A ribosomal protein L35a
RPS4Y1 ribosomal protein S4, Y-linked 1
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SMR3B submaxillary gland androgen regulated protein 3B
SNX1 sorting nexin 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPTBN5 spectrin, beta, non-erythrocytic 5
SSX3 synovial sarcoma, X breakpoint 3
STAG3 stromal antigen 3
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAGLN3 transgelin 3
TBXA2R thromboxane A2 receptor
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPMT thiopurine S-methyltransferase
TPSG1 tryptase gamma 1
TRD T cell receptor delta locus
TRIB2 tribbles pseudokinase 2
TRIL TLR4 interactor with leucine-rich repeats
TTC38 tetratricopeptide repeat domain 38
UNC5B unc-5 homolog B (C. elegans)
WNT16 wingless-type MMTV integration site family, member 16
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XYLB xylulokinase homolog (H. influenzae)
ZMAT4 zinc finger, matrin-type 4
ZNF646 zinc finger protein 646

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADGRG2 adhesion G protein-coupled receptor G2
AFAP1 actin filament associated protein 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARSB arylsulfatase B
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
BCORL1 BCL6 corepressor-like 1
C19ORF73 chromosome 19 open reading frame 73
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CALML5 calmodulin-like 5
CCNK cyclin K
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CNTNAP1 contactin associated protein 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DCAF4 DDB1 and CUL4 associated factor 4
DGAT1 diacylglycerol O-acyltransferase 1
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNM3 dynamin 3
ERCC5 excision repair cross-complementation group 5
FBXL15 F-box and leucine-rich repeat protein 15
FBXL7 F-box and leucine-rich repeat protein 7
FBXO2 F-box protein 2
FER fer (fps/fes related) tyrosine kinase
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUZ fuzzy planar cell polarity protein
GLDC glycine dehydrogenase (decarboxylating)
GMPR guanosine monophosphate reductase
GPATCH4 G patch domain containing 4
HDAC11 histone deacetylase 11
HIST1H2AI histone cluster 1, H2ai
HIST1H2BO histone cluster 1, H2bo
HOXC8 homeobox C8
HPX hemopexin
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HYAL1 hyaluronoglucosaminidase 1
IDI2-AS1 IDI2 antisense RNA 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL22 interleukin 22
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM5C lysine (K)-specific demethylase 5C
KDM8 lysine (K)-specific demethylase 8
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LIME1 Lck interacting transmembrane adaptor 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGEA5 melanoma antigen family A5
MBTPS2 membrane-bound transcription factor peptidase, site 2
MFGE8 milk fat globule-EGF factor 8 protein
MITF microphthalmia-associated transcription factor
MRPS18C mitochondrial ribosomal protein S18C
MST1R macrophage stimulating 1 receptor
MTL5 metallothionein-like 5, testis-specific (tesmin)
NACA2 nascent polypeptide-associated complex alpha subunit 2
NCALD neurocalcin delta
NEUROD4 neuronal differentiation 4
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPM3 nucleophosmin/nucleoplasmin 3
NT5DC3 5'-nucleotidase domain containing 3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUP62CL nucleoporin 62kDa C-terminal like
NXPE3 neurexophilin and PC-esterase domain family, member 3
ODF2 outer dense fiber of sperm tails 2
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PALM paralemmin
PHF14 PHD finger protein 14
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCD1 phospholipase C, delta 1
PPP1R9A protein phosphatase 1, regulatory subunit 9A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFPL1S RFPL1 antisense RNA 1
RNF126P1 ring finger protein 126 pseudogene 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SEC14L2 SEC14-like 2 (S. cerevisiae)
SECTM1 secreted and transmembrane 1
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERGEF secretion regulating guanine nucleotide exchange factor
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SNX15 sorting nexin 15
SP1 Sp1 transcription factor
STK16 serine/threonine kinase 16
SYT17 synaptotagmin XVII
TBKBP1 TBK1 binding protein 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TH tyrosine hydroxylase
TMEM254 transmembrane protein 254
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TOM1 target of myb1 (chicken)
TUBA3C tubulin, alpha 3c
UNC93B1 unc-93 homolog B1 (C. elegans)
UPK2 uroplakin 2
UPP1 uridine phosphorylase 1
XYLT1 xylosyltransferase I
ZNF227 zinc finger protein 227
ZNF37BP zinc finger protein 37B, pseudogene
ZNF552 zinc finger protein 552