| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the esculin-5411 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADD2 | adducin 2 (beta) |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BCAN | brevican |
| BFSP2 | beaded filament structural protein 2, phakinin |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BMP3 | bone morphogenetic protein 3 |
| BTC | betacellulin |
| C11ORF21 | chromosome 11 open reading frame 21 |
| CALB1 | calbindin 1, 28kDa |
| CD83 | CD83 molecule |
| CDC14B | cell division cycle 14B |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLMN | calmin (calponin-like, transmembrane) |
| CRLF1 | cytokine receptor-like factor 1 |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| CYBB | cytochrome b-245, beta polypeptide |
| CYP3A7 | cytochrome P450, family 3, subfamily A, polypeptide 7 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 |
| ELAC2 | elaC ribonuclease Z 2 |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| ERCC2 | excision repair cross-complementation group 2 |
| EVA1B | eva-1 homolog B (C. elegans) |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FFAR2 | free fatty acid receptor 2 |
| FGA | fibrinogen alpha chain |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GHRHR | growth hormone releasing hormone receptor |
| GLRA1 | glycine receptor, alpha 1 |
| GM2A | GM2 ganglioside activator |
| GPM6A | glycoprotein M6A |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HEPH | hephaestin |
| HFE | hemochromatosis |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IRF4 | interferon regulatory factor 4 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNV2 | potassium channel, voltage gated modifier subfamily V, member 2 |
| KIAA1324 | KIAA1324 |
| KLF13 | Kruppel-like factor 13 |
| LAMC2 | laminin, gamma 2 |
| LEPR | leptin receptor |
| LIN7B | lin-7 homolog B (C. elegans) |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| LOC79999 | uncharacterized LOC79999 |
| LTK | leukocyte receptor tyrosine kinase |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MAL | mal, T-cell differentiation protein |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MED16 | mediator complex subunit 16 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MSI1 | musashi RNA-binding protein 1 |
| MSX2 | msh homeobox 2 |
| MYO7A | myosin VIIA |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| PCDH17 | protocadherin 17 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PHYHIP | phytanoyl-CoA 2-hydroxylase interacting protein |
| PIDD1 | p53-induced death domain protein 1 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| POU4F1 | POU class 4 homeobox 1 |
| PPARA | peroxisome proliferator-activated receptor alpha |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| RORA | RAR-related orphan receptor A |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SNX13 | sorting nexin 13 |
| SOD3 | superoxide dismutase 3, extracellular |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| T | T, brachyury homolog (mouse) |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TRIM29 | tripartite motif containing 29 |
| TTC39A | tetratricopeptide repeat domain 39A |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF747 | zinc finger protein 747 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| BBC3 | BCL2 binding component 3 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| BST2 | bone marrow stromal cell antigen 2 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC94 | coiled-coil domain containing 94 |
| CEP85 | centrosomal protein 85kDa |
| CFAP44 | cilia and flagella associated protein 44 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CLSPN | claspin |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| FAM212B | family with sequence similarity 212, member B |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| IFI27 | interferon, alpha-inducible protein 27 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| INO80D | INO80 complex subunit D |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KAT2A | K(lysine) acetyltransferase 2A |
| KIZ | kizuna centrosomal protein |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KRT15 | keratin 15, type I |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MCOLN1 | mucolipin 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MXD3 | MAX dimerization protein 3 |
| MYOZ3 | myozenin 3 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PCDHA6 | protocadherin alpha 6 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PER3 | period circadian clock 3 |
| PLXNA3 | plexin A3 |
| POM121 | POM121 transmembrane nucleoporin |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RIN2 | Ras and Rab interactor 2 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| S100A4 | S100 calcium binding protein A4 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAI | suppressor of cancer cell invasion |
| SCPEP1 | serine carboxypeptidase 1 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SETD1A | SET domain containing 1A |
| SIRAL2 | SIR2 antiphage like 2 |
| SIRT6 | sirtuin 6 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SMIM14 | small integral membrane protein 14 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM242 | transmembrane protein 242 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TTC33 | tetratricopeptide repeat domain 33 |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| VEGFC | vascular endothelial growth factor C |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR60 | WD repeat domain 60 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF248 | zinc finger protein 248 |
| ZNF778 | zinc finger protein 778 |
| ZNF804A | zinc finger protein 804A |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
