| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the esculin-6310 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABI2 | abl-interactor 2 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANAPC5 | anaphase promoting complex subunit 5 |
| APOE | apolipoprotein E |
| APOM | apolipoprotein M |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ATXN2L | ataxin 2-like |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BEX4 | brain expressed, X-linked 4 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| CALD1 | caldesmon 1 |
| CAPN5 | calpain 5 |
| CASZ1 | castor zinc finger 1 |
| CCDC88A | coiled-coil domain containing 88A |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| EFNA3 | ephrin-A3 |
| EFNB3 | ephrin-B3 |
| EGFR | epidermal growth factor receptor |
| EML3 | echinoderm microtubule associated protein like 3 |
| EXOG | endo/exonuclease (5'-3'), endonuclease G-like |
| FBXO31 | F-box protein 31 |
| FKBP15 | FK506 binding protein 15, 133kDa |
| GAS8 | growth arrest-specific 8 |
| GTF2I | general transcription factor IIi |
| GYPA | glycophorin A (MNS blood group) |
| HDAC11 | histone deacetylase 11 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IFFO1 | intermediate filament family orphan 1 |
| INO80D | INO80 complex subunit D |
| IPO8 | importin 8 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 |
| KLF12 | Kruppel-like factor 12 |
| KLHL36 | kelch-like family member 36 |
| KRT6B | keratin 6B, type II |
| KRT9 | keratin 9, type I |
| LAT2 | linker for activation of T cells family, member 2 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LMAN1 | lectin, mannose-binding, 1 |
| LOC81691 | exonuclease NEF-sp |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MAT2A | methionine adenosyltransferase II, alpha |
| MCL1 | myeloid cell leukemia 1 |
| MED16 | mediator complex subunit 16 |
| MFN2 | mitofusin 2 |
| MON1B | MON1 secretory trafficking family member B |
| MST1 | macrophage stimulating 1 |
| NKX3-2 | NK3 homeobox 2 |
| NNAT | neuronatin |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NRP1 | neuropilin 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| PAPPA2 | pappalysin 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PIDD1 | p53-induced death domain protein 1 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLD3 | phospholipase D family, member 3 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PROSC | proline synthetase co-transcribed homolog (bacterial) |
| RABGGTA | Rab geranylgeranyltransferase, alpha subunit |
| RANGAP1 | Ran GTPase activating protein 1 |
| RARG | retinoic acid receptor, gamma |
| RHEB | Ras homolog enriched in brain |
| SCAMP1 | secretory carrier membrane protein 1 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SFRP1 | secreted frizzled-related protein 1 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPRYD7 | SPRY domain containing 7 |
| SSH3 | slingshot protein phosphatase 3 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 |
| TAPBP | TAP binding protein (tapasin) |
| TRABD | TraB domain containing |
| TSPAN1 | tetraspanin 1 |
| VARS | valyl-tRNA synthetase |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF573 | zinc finger protein 573 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CCNL2 | cyclin L2 |
| CCNT1 | cyclin T1 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CENPO | centromere protein O |
| CEP85 | centrosomal protein 85kDa |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CNTNAP1 | contactin associated protein 1 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| FAM102A | family with sequence similarity 102, member A |
| FAM131A | family with sequence similarity 131, member A |
| FANCF | Fanconi anemia, complementation group F |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FUZ | fuzzy planar cell polarity protein |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GALK1 | galactokinase 1 |
| GMIP | GEM interacting protein |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR176 | G protein-coupled receptor 176 |
| GSTT1 | glutathione S-transferase theta 1 |
| GTPBP2 | GTP binding protein 2 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HOXA2 | homeobox A2 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IFI35 | interferon-induced protein 35 |
| IFT81 | intraflagellar transport 81 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IRF1 | interferon regulatory factor 1 |
| IRGQ | immunity-related GTPase family, Q |
| KLHL12 | kelch-like family member 12 |
| LINS | lines homolog (Drosophila) |
| LOC729164 | hCG1732469 |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAGEH1 | melanoma antigen family H1 |
| MCCC1 | methylcrotonoyl-CoA carboxylase 1 (alpha) |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MLYCD | malonyl-CoA decarboxylase |
| MMP1 | matrix metallopeptidase 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDE1 | nudE neurodevelopment protein 1 |
| NDP | Norrie disease (pseudoglioma) |
| NLRX1 | NLR family member X1 |
| NOTCH1 | notch 1 |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDE12 | phosphodiesterase 12 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PSKH1 | protein serine kinase H1 |
| PTGES2 | prostaglandin E synthase 2 |
| RAB5B | RAB5B, member RAS oncogene family |
| RASA2 | RAS p21 protein activator 2 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF31 | ring finger protein 31 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SMAD7 | SMAD family member 7 |
| SNTA1 | syntrophin, alpha 1 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAOK1 | TAO kinase 1 |
| TIGD6 | tigger transposable element derived 6 |
| TMEM120B | transmembrane protein 120B |
| TMEM121 | transmembrane protein 121 |
| TMEM132A | transmembrane protein 132A |
| TOR4A | torsin family 4, member A |
| TRIM66 | tripartite motif containing 66 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TUBA4B | tubulin, alpha 4b |
| UBXN2B | UBX domain protein 2B |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 |
| ULBP2 | UL16 binding protein 2 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| ZNF282 | zinc finger protein 282 |
| ZNF34 | zinc finger protein 34 |
| ZNF862 | zinc finger protein 862 |
