esophagus Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A muscular tube that in humans is about nine inches (23 centimeters) long and passes from the pharynx down the neck between the trachea and the spinal column and behind the left bronchus where it pierces the diaphragm slightly to the left of the middle line and joins the cardiac end of the stomach. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000959)
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Genes

187 genes co-occuring with the biological term esophagus in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACKR3 atypical chemokine receptor 3
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
AHCY adenosylhomocysteinase
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C2 aldo-keto reductase family 1, member C2
AMACR alpha-methylacyl-CoA racemase
APC adenomatous polyposis coli
AR androgen receptor
ATOH1 atonal homolog 1 (Drosophila)
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
AXIN1 axin 1
BMP4 bone morphogenetic protein 4
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C15ORF48 chromosome 15 open reading frame 48
C1QA complement component 1, q subcomponent, A chain
CALR calreticulin
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle)
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CCNA2 cyclin A2
CCNE1 cyclin E1
CD44 CD44 molecule (Indian blood group)
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDK1 cyclin-dependent kinase 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX1 caudal type homeobox 1
CDX2 caudal type homeobox 2
CES2 carboxylesterase 2
CLDN1 claudin 1
COL10A1 collagen, type X, alpha 1
COL4A5 collagen, type IV, alpha 5
COL4A6 collagen, type IV, alpha 6
CRNN cornulin
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSD cathepsin D
CXADR coxsackie virus and adenovirus receptor
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DCLK1 doublecortin-like kinase 1
DEFB103B defensin, beta 103B
DKK1 dickkopf WNT signaling pathway inhibitor 1
DSE dermatan sulfate epimerase
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EGFR epidermal growth factor receptor
EMP1 epithelial membrane protein 1
EPCAM epithelial cell adhesion molecule
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERO1L ERO1-like (S. cerevisiae)
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAS Fas cell surface death receptor
FASN fatty acid synthase
FGF2 fibroblast growth factor 2 (basic)
FOXF1 forkhead box F1
GATA6 GATA binding protein 6
GPX1 glutathione peroxidase 1
GPX2 glutathione peroxidase 2
GPX3 glutathione peroxidase 3
GSTM1 glutathione S-transferase mu 1
GSTO1 glutathione S-transferase omega 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GUCY2C guanylate cyclase 2C
HDAC1 histone deacetylase 1
HDGF hepatoma-derived growth factor
HFE hemochromatosis
HFE2 hemochromatosis type 2 (juvenile)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HOXB5 homeobox B5
HOXB6 homeobox B6
HOXB7 homeobox B7
HSPA4 heat shock 70kDa protein 4
HSPB1 heat shock 27kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
ICAM1 intercellular adhesion molecule 1
ICAM2 intercellular adhesion molecule 2
ICAM3 intercellular adhesion molecule 3
IGF1R insulin-like growth factor 1 receptor
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL13 interleukin 13
IL18 interleukin 18
IL19 interleukin 19
IL23R interleukin 23 receptor
IL6 interleukin 6
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT20 keratin 20, type I
KRT7 keratin 7, type II
LCE3D late cornified envelope 3D
LEP leptin
LEPR leptin receptor
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LTA lymphotoxin alpha
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAL mal, T-cell differentiation protein
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MGMT O-6-methylguanine-DNA methyltransferase
MIR205 microRNA 205
MIR21 microRNA 21
MIR31 microRNA 31
MIR375 microRNA 375
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MTA1 metastasis associated 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC1 mucin 1, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO9B myosin IXB
NOTCH1 notch 1
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR1I2 nuclear receptor subfamily 1, group I, member 2
NRP1 neuropilin 1
OCLN occludin
OGG1 8-oxoguanine DNA glycosylase
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDPN podoplanin
PDS5B PDS5 cohesin associated factor B
PGA3 pepsinogen 3, group I (pepsinogen A)
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PITX1 paired-like homeodomain 1
PKP1 plakophilin 1
PLN phospholamban
POSTN periostin, osteoblast specific factor
POU5F1 POU class 5 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PRDX1 peroxiredoxin 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAD51 RAD51 recombinase
RBL2 retinoblastoma-like 2
REG1A regenerating islet-derived 1 alpha
RELN reelin
RETN resistin
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RUNX3 runt-related transcription factor 3
S100A2 S100 calcium binding protein A2
SEPP1 selenoprotein P, plasma, 1
SFRP1 secreted frizzled-related protein 1
SIRT1 sirtuin 1
SKI SKI proto-oncogene
SKIL SKI-like proto-oncogene
SMTN smoothelin
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOD2 superoxide dismutase 2, mitochondrial
SOX2 SRY (sex determining region Y)-box 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TERT telomerase reverse transcriptase
TFF1 trefoil factor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TK1 thymidine kinase 1, soluble
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2
TMEM97 transmembrane protein 97
TMPRSS11B transmembrane protease, serine 11B
TP53 tumor protein p53
TP63 tumor protein p63
TPM1 tropomyosin 1 (alpha)
TSC1 tuberous sclerosis 1
UMPS uridine monophosphate synthetase
VEGFA vascular endothelial growth factor A
WIF1 WNT inhibitory factor 1
WNT2 wingless-type MMTV integration site family member 2
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1