esotropia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description Esotropia is a strabismus in which the eye turns inward toward the nose. (Human Disease Ontology, DOID_9840)
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Genes

78 genes co-occuring with the disease esotropia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
LMLN leishmanolysin-like (metallopeptidase M8 family) 1.72639
PRELID1 PRELI domain containing 1 1.4913
EBP emopamil binding protein (sterol isomerase) 1.40176
CHN1 chimerin 1 1.34592
GLRB glycine receptor, beta 1.14942
ZC3H13 zinc finger CCCH-type containing 13 1.13839
SURF1 surfeit 1 1.07362
UBE2A ubiquitin-conjugating enzyme E2A 1.03409
PDLIM1 PDZ and LIM domain 1 1.01554
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 1.0109
PMM2 phosphomannomutase 2 0.999924
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 0.975903
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 0.965825
DDT D-dopachrome tautomerase 0.936214
FRMD7 FERM domain containing 7 0.901978
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 0.890488
PPT1 palmitoyl-protein thioesterase 1 0.880653
FOXL2 forkhead box L2 0.874919
ADGRG1 adhesion G protein-coupled receptor G1 0.873281
VANGL2 VANGL planar cell polarity protein 2 0.870006
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.867549
PTCH1 patched 1 0.859362
EVC2 Ellis van Creveld syndrome 2 0.859362
OSTM1 osteopetrosis associated transmembrane protein 1 0.821257
COL9A1 collagen, type IX, alpha 1 0.814693
NMS neuromedin S 0.796232
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.75005
TBCE tubulin folding cofactor E 0.727738
CLCN7 chloride channel, voltage-sensitive 7 0.718039
EVC Ellis van Creveld protein 0.703134
KIF21A kinesin family member 21A 0.701526
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 0.687491
HTN3 histatin 3 0.640645
FBLIM1 filamin binding LIM protein 1 0.640251
NR2E3 nuclear receptor subfamily 2, group E, member 3 0.632777
CYCS cytochrome c, somatic 0.631991
YARS tyrosyl-tRNA synthetase 0.630813
EFNB1 ephrin-B1 0.617094
DPT dermatopontin 0.615138
COL11A1 collagen, type XI, alpha 1 0.612792
DSE dermatan sulfate epimerase 0.606543
FZD4 frizzled class receptor 4 0.60108
CLCN1 chloride channel, voltage-sensitive 1 0.580439
GREM2 gremlin 2, DAN family BMP antagonist 0.578494
GK glycerol kinase 0.550911
EFNB2 ephrin-B2 0.550522
TYRP1 tyrosinase-related protein 1 0.517265
EP300 E1A binding protein p300 0.496175
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.454847
TBP TATA box binding protein 0.428516
HEXB hexosaminidase B (beta polypeptide) 0.415773
FGF19 fibroblast growth factor 19 0.407172
AXL AXL receptor tyrosine kinase 0.394491
LRP2 low density lipoprotein receptor-related protein 2 0.385193
PTER phosphotriesterase related 0.384079
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.382594
WDFY2 WD repeat and FYVE domain containing 2 0.367779
MCM8 minichromosome maintenance complex component 8 0.362609
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.359289
TF transferrin 0.356709
CREBBP CREB binding protein 0.348981
LARS leucyl-tRNA synthetase 0.34384
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.335778
COL2A1 collagen, type II, alpha 1 0.321545
PKD1P6 polycystic kidney disease 1 (autosomal dominant) pseudogene 6 0.316092
FOXP2 forkhead box P2 0.315366
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.294053
BSG basigin (Ok blood group) 0.263014
ATP7B ATPase, Cu++ transporting, beta polypeptide 0.260184
PIDD1 p53-induced death domain protein 1 0.254888
PAX6 paired box 6 0.254183
F12 coagulation factor XII (Hageman factor) 0.248203
CA2 carbonic anhydrase II 0.234225
HEXA hexosaminidase A (alpha polypeptide) 0.229024
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.218034
OXA1L oxidase (cytochrome c) assembly 1-like 0.196779
SUMO2 small ubiquitin-like modifier 2 0.188632
FGFR3 fibroblast growth factor receptor 3 0.164359