| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
196 genes differentially expressed following the estradiol-1021 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| AFF4 | AF4/FMR2 family, member 4 |
| AJAP1 | adherens junctions associated protein 1 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AP2S1 | adaptor-related protein complex 2, sigma 1 subunit |
| APBA3 | amyloid beta (A4) precursor protein-binding, family A, member 3 |
| APP | amyloid beta (A4) precursor protein |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP11A | ATPase, class VI, type 11A |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BTN2A1 | butyrophilin, subfamily 2, member A1 |
| C16ORF58 | chromosome 16 open reading frame 58 |
| CA11 | carbonic anhydrase XI |
| CBX7 | chromobox homolog 7 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLDN15 | claudin 15 |
| COPS8 | COP9 signalosome subunit 8 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DVL2 | dishevelled segment polarity protein 2 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal |
| EGR3 | early growth response 3 |
| EPS8L1 | EPS8-like 1 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FANCA | Fanconi anemia, complementation group A |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPR21 | G protein-coupled receptor 21 |
| GRK5 | G protein-coupled receptor kinase 5 |
| HIST1H1D | histone cluster 1, H1d |
| HOXB2 | homeobox B2 |
| HSPB11 | heat shock protein family B (small), member 11 |
| INHBE | inhibin, beta E |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| JAK2 | Janus kinase 2 |
| KIF13A | kinesin family member 13A |
| KLF10 | Kruppel-like factor 10 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LARS2 | leucyl-tRNA synthetase 2, mitochondrial |
| LOC644450 | uncharacterized LOC644450 |
| MBTD1 | mbt domain containing 1 |
| MED6 | mediator complex subunit 6 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| NAV2 | neuron navigator 2 |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| PCBP3 | poly(rC) binding protein 3 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDZK1 | PDZ domain containing 1 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PITX1 | paired-like homeodomain 1 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PLXNA1 | plexin A1 |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PRAF2 | PRA1 domain family, member 2 |
| PRKD3 | protein kinase D3 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| S100A8 | S100 calcium binding protein A8 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SETD4 | SET domain containing 4 |
| SFTPB | surfactant protein B |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SIK3 | SIK family kinase 3 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SOCS6 | suppressor of cytokine signaling 6 |
| SRSF8 | serine/arginine-rich splicing factor 8 |
| ST5 | suppression of tumorigenicity 5 |
| SUN1 | Sad1 and UNC84 domain containing 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| TBC1D17 | TBC1 domain family, member 17 |
| TGM2 | transglutaminase 2 |
| THBD | thrombomodulin |
| TMPRSS3 | transmembrane protease, serine 3 |
| TSPYL2 | TSPY-like 2 |
| TTBK2 | tau tubulin kinase 2 |
| TUBA3C | tubulin, alpha 3c |
| UBOX5 | U-box domain containing 5 |
| VEGFA | vascular endothelial growth factor A |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF286A | zinc finger protein 286A |
| ZNF34 | zinc finger protein 34 |
| ZNF573 | zinc finger protein 573 |
| ZNF580 | zinc finger protein 580 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ACVR2B | activin A receptor, type IIB |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARL15 | ADP-ribosylation factor-like 15 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BBC3 | BCL2 binding component 3 |
| BCOR | BCL6 corepressor |
| BMP4 | bone morphogenetic protein 4 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCDC130 | coiled-coil domain containing 130 |
| CCDC68 | coiled-coil domain containing 68 |
| CCNK | cyclin K |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COL4A5 | collagen, type IV, alpha 5 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTAGE9 | CTAGE family, member 9 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EFNA1 | ephrin-A1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| FKBP5 | FK506 binding protein 5 |
| GALK1 | galactokinase 1 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLB1L | galactosidase, beta 1-like |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HS1BP3 | HCLS1 binding protein 3 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IREB2 | iron-responsive element binding protein 2 |
| IRF7 | interferon regulatory factor 7 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIAA0513 | KIAA0513 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC20 | leucine rich repeat containing 20 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MCC | mutated in colorectal cancers |
| MDM4 | MDM4, p53 regulator |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MT1HL1 | metallothionein 1H-like 1 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PODXL2 | podocalyxin-like 2 |
| POLH | polymerase (DNA directed), eta |
| POM121 | POM121 transmembrane nucleoporin |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha |
| PVRL3 | poliovirus receptor-related 3 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF2 | ring finger protein 2 |
| RNF39 | ring finger protein 39 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCHIP1 | schwannomin interacting protein 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SCRN3 | secernin 3 |
| SIRT2 | sirtuin 2 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SNAI2 | snail family zinc finger 2 |
| SPIDR | scaffolding protein involved in DNA repair |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TNRC6B | trinucleotide repeat containing 6B |
| TNS2 | tensin 2 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRIM36 | tripartite motif containing 36 |
| TUBA3D | tubulin, alpha 3d |
| XK | X-linked Kx blood group |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZFAND3 | zinc finger, AN1-type domain 3 |
| ZNF710 | zinc finger protein 710 |
