| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the estradiol-1079 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| ARMC8 | armadillo repeat containing 8 |
| ATP11A | ATPase, class VI, type 11A |
| AXIN1 | axin 1 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| BMP1 | bone morphogenetic protein 1 |
| BRE | brain and reproductive organ-expressed (TNFRSF1A modulator) |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C17ORF75 | chromosome 17 open reading frame 75 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CCNG2 | cyclin G2 |
| CENPQ | centromere protein Q |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CREBZF | CREB/ATF bZIP transcription factor |
| CRYL1 | crystallin, lambda 1 |
| CTBS | chitobiase, di-N-acetyl- |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DDX52 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DIAPH1 | diaphanous-related formin 1 |
| DND1 | DND microRNA-mediated repression inhibitor 1 |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 |
| EFNA3 | ephrin-A3 |
| EGR3 | early growth response 3 |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| EIF1 | eukaryotic translation initiation factor 1 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FADS3 | fatty acid desaturase 3 |
| FEM1C | fem-1 homolog c (C. elegans) |
| FGFR2 | fibroblast growth factor receptor 2 |
| FOXC1 | forkhead box C1 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FXR2 | fragile X mental retardation, autosomal homolog 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| HABP4 | hyaluronan binding protein 4 |
| HSF1 | heat shock transcription factor 1 |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| ITGB5 | integrin, beta 5 |
| JUN | jun proto-oncogene |
| KAT2A | K(lysine) acetyltransferase 2A |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLHL22 | kelch-like family member 22 |
| KPTN | kaptin (actin binding protein) |
| MANEA | mannosidase, endo-alpha |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MEIS1 | Meis homeobox 1 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NIPBL | Nipped-B homolog (Drosophila) |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 |
| OGFR | opioid growth factor receptor |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PDZK1 | PDZ domain containing 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLK4 | polo-like kinase 4 |
| POLDIP3 | polymerase (DNA-directed), delta interacting protein 3 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PVR | poliovirus receptor |
| RAB28 | RAB28, member RAS oncogene family |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
| SLK | STE20-like kinase |
| SMA4 | glucuronidase, beta pseudogene |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SOAT1 | sterol O-acyltransferase 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STC1 | stanniocalcin 1 |
| STX2 | syntaxin 2 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 |
| TBL1X | transducin (beta)-like 1X-linked |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TGFA | transforming growth factor, alpha |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 |
| TMEM194A | transmembrane protein 194A |
| TMEM2 | transmembrane protein 2 |
| TOP3A | topoisomerase (DNA) III alpha |
| TWF2 | twinfilin actin binding protein 2 |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) |
| UBE3C | ubiquitin protein ligase E3C |
| WDHD1 | WD repeat and HMG-box DNA binding protein 1 |
| WDR48 | WD repeat domain 48 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF124 | zinc finger protein 124 |
| Symbol | Name |
|---|---|
| AEN | apoptosis enhancing nuclease |
| ANKMY2 | ankyrin repeat and MYND domain containing 2 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ARMC7 | armadillo repeat containing 7 |
| ASB8 | ankyrin repeat and SOCS box containing 8 |
| ATG2A | autophagy related 2A |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BBC3 | BCL2 binding component 3 |
| C12ORF43 | chromosome 12 open reading frame 43 |
| C19ORF24 | chromosome 19 open reading frame 24 |
| C1ORF216 | chromosome 1 open reading frame 216 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| C5 | complement component 5 |
| CBR4 | carbonyl reductase 4 |
| CCNL2 | cyclin L2 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CEP83 | centrosomal protein 83kDa |
| CHKB | choline kinase beta |
| CHMP7 | charged multivesicular body protein 7 |
| CLDN9 | claudin 9 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CTSV | cathepsin V |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DHDDS | dehydrodolichyl diphosphate synthase |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DNA2 | DNA replication helicase/nuclease 2 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) |
| ECD | ecdysoneless homolog (Drosophila) |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 |
| EFNA1 | ephrin-A1 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERCC5 | excision repair cross-complementation group 5 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FAM172A | family with sequence similarity 172, member A |
| FBXO46 | F-box protein 46 |
| FDXR | ferredoxin reductase |
| FOCAD | focadhesin |
| FOXJ2 | forkhead box J2 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2BF | histone cluster 1, H2bf |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IP6K1 | inositol hexakisphosphate kinase 1 |
| JADE1 | jade family PHD finger 1 |
| JUNB | jun B proto-oncogene |
| KLHL21 | kelch-like family member 21 |
| LIN37 | lin-37 DREAM MuvB core complex component |
| LRP10 | low density lipoprotein receptor-related protein 10 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 |
| MB | myoglobin |
| MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MYLIP | myosin regulatory light chain interacting protein |
| NABP2 | nucleic acid binding protein 2 |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NUBPL | nucleotide binding protein-like |
| ORC3 | origin recognition complex, subunit 3 |
| PADI2 | peptidyl arginine deiminase, type II |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PKN1 | protein kinase N1 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| PPOX | protoporphyrinogen oxidase |
| PRSS8 | protease, serine, 8 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYTL2 | synaptotagmin-like 2 |
| TESK2 | testis-specific kinase 2 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM115 | transmembrane protein 115 |
| TMEM132A | transmembrane protein 132A |
| TMEM183A | transmembrane protein 183A |
| TRIP10 | thyroid hormone receptor interactor 10 |
| TXLNA | taxilin alpha |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 |
| UNC13B | unc-13 homolog B (C. elegans) |
| VPS37C | vacuolar protein sorting 37 homolog C (S. cerevisiae) |
| WDR60 | WD repeat domain 60 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF672 | zinc finger protein 672 |
| ZNF675 | zinc finger protein 675 |
| ZNF721 | zinc finger protein 721 |
