| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the estradiol-1149 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| AMT | aminomethyltransferase |
| APP | amyloid beta (A4) precursor protein |
| AREG | amphiregulin |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ATG10 | autophagy related 10 |
| ATG3 | autophagy related 3 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CCDC22 | coiled-coil domain containing 22 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CFAP69 | cilia and flagella associated protein 69 |
| CLEC4A | C-type lectin domain family 4, member A |
| CLIC5 | chloride intracellular channel 5 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DCTN1 | dynactin 1 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| EMD | emerin |
| FAM49B | family with sequence similarity 49, member B |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) |
| FCHO1 | FCH domain only 1 |
| FGF4 | fibroblast growth factor 4 |
| FHL3 | four and a half LIM domains 3 |
| FLOT1 | flotillin 1 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GID4 | GID complex subunit 4 |
| GLIPR1 | GLI pathogenesis-related 1 |
| GOLGA2 | golgin A2 |
| GOSR1 | golgi SNAP receptor complex member 1 |
| GPX2 | glutathione peroxidase 2 |
| HIST1H1T | histone cluster 1, H1t |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| ING4 | inhibitor of growth family, member 4 |
| INO80B | INO80 complex subunit B |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| KLF6 | Kruppel-like factor 6 |
| LAG3 | lymphocyte-activation gene 3 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LYRM9 | LYR motif containing 9 |
| MAGEA8 | melanoma antigen family A8 |
| MED13L | mediator complex subunit 13-like |
| METTL7A | methyltransferase like 7A |
| MMP25 | matrix metallopeptidase 25 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PHACTR2 | phosphatase and actin regulator 2 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLK3 | polo-like kinase 3 |
| PLK4 | polo-like kinase 4 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RAB28 | RAB28, member RAS oncogene family |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) |
| RANBP3 | RAN binding protein 3 |
| RBM26 | RNA binding motif protein 26 |
| REEP4 | receptor accessory protein 4 |
| REST | RE1-silencing transcription factor |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SSH3 | slingshot protein phosphatase 3 |
| STAT5B | signal transducer and activator of transcription 5B |
| SYN2 | synapsin II |
| TAS2R1 | taste receptor, type 2, member 1 |
| TEX261 | testis expressed 261 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TPMT | thiopurine S-methyltransferase |
| TRAF1 | TNF receptor-associated factor 1 |
| TULP3 | tubby like protein 3 |
| UBQLN4 | ubiquilin 4 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| WSB2 | WD repeat and SOCS box containing 2 |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| ZNF93 | zinc finger protein 93 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| AGO4 | argonaute RISC catalytic component 4 |
| AKTIP | AKT interacting protein |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARRB2 | arrestin, beta 2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BBS7 | Bardet-Biedl syndrome 7 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CAPN15 | calpain 15 |
| CCNJ | cyclin J |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CHML | choroideremia-like (Rab escort protein 2) |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CRTAP | cartilage associated protein |
| CSF1R | colony stimulating factor 1 receptor |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERCC2 | excision repair cross-complementation group 2 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| ETV4 | ets variant 4 |
| EXOC2 | exocyst complex component 2 |
| FAM127A | family with sequence similarity 127, member A |
| FAM172A | family with sequence similarity 172, member A |
| FAM204A | family with sequence similarity 204, member A |
| G6PD | glucose-6-phosphate dehydrogenase |
| GID8 | GID complex subunit 8 |
| GPR27 | G protein-coupled receptor 27 |
| HDAC5 | histone deacetylase 5 |
| HIRA | histone cell cycle regulator |
| HIST2H2BE | histone cluster 2, H2be |
| HOOK2 | hook microtubule-tethering protein 2 |
| HPSE | heparanase |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| KIAA0430 | KIAA0430 |
| MAGEB2 | melanoma antigen family B2 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| METTL8 | methyltransferase like 8 |
| MKL2 | MKL/myocardin-like 2 |
| MOSPD3 | motile sperm domain containing 3 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLTP | phospholipid transfer protein |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRDM13 | PR domain containing 13 |
| PROS1 | protein S (alpha) |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| RPL39L | ribosomal protein L39-like |
| RPP38 | ribonuclease P/MRP 38kDa subunit |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SCRN3 | secernin 3 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMAD5 | SMAD family member 5 |
| SMAD7 | SMAD family member 7 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPATA2L | spermatogenesis associated 2-like |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| STRN4 | striatin, calmodulin binding protein 4 |
| TBL3 | transducin (beta)-like 3 |
| TCTA | T-cell leukemia translocation altered |
| TESK2 | testis-specific kinase 2 |
| TMEM159 | transmembrane protein 159 |
| TMEM209 | transmembrane protein 209 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TPCN1 | two pore segment channel 1 |
| TRIM45 | tripartite motif containing 45 |
| TRIM52 | tripartite motif containing 52 |
| TTC26 | tetratricopeptide repeat domain 26 |
| TUBA3C | tubulin, alpha 3c |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VANGL1 | VANGL planar cell polarity protein 1 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF506 | zinc finger protein 506 |
| ZNF675 | zinc finger protein 675 |
| ZNF816 | zinc finger protein 816 |
