estradiol-1182 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the estradiol-1182 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARHGAP1 Rho GTPase activating protein 1
ASIC1 acid sensing (proton gated) ion channel 1
AXIN1 axin 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C6ORF47 chromosome 6 open reading frame 47
CAPN5 calpain 5
CD58 CD58 molecule
CDK3 cyclin-dependent kinase 3
CLEC4A C-type lectin domain family 4, member A
CRYL1 crystallin, lambda 1
CTNNBIP1 catenin, beta interacting protein 1
CTNND1 catenin (cadherin-associated protein), delta 1
CTSS cathepsin S
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DSPP dentin sialophosphoprotein
DUSP7 dual specificity phosphatase 7
DVL2 dishevelled segment polarity protein 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FAM53C family with sequence similarity 53, member C
FCHO1 FCH domain only 1
FER1L4 fer-1-like family member 4, pseudogene (functional)
FH fumarate hydratase
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GSTA4 glutathione S-transferase alpha 4
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HSPA1L heat shock 70kDa protein 1-like
IDS iduronate 2-sulfatase
INHBC inhibin, beta C
INO80B INO80 complex subunit B
IRX5 iroquois homeobox 5
JAG1 jagged 1
JRK Jrk homolog (mouse)
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KLF6 Kruppel-like factor 6
KLHDC10 kelch domain containing 10
KLHL20 kelch-like family member 20
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LRP6 low density lipoprotein receptor-related protein 6
MAGOH2P mago-nashi homolog 2, pseudogene
METTL7A methyltransferase like 7A
MIIP migration and invasion inhibitory protein
MSRB2 methionine sulfoxide reductase B2
MYBBP1A MYB binding protein (P160) 1a
NAG18 NAG18 mRNA
NOP16 NOP16 nucleolar protein
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHGB5 protocadherin gamma subfamily B, 5
PDCD2 programmed cell death 2
PDLIM7 PDZ and LIM domain 7 (enigma)
PHTF2 putative homeodomain transcription factor 2
PKP4 plakophilin 4
PLK3 polo-like kinase 3
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPP5C protein phosphatase 5, catalytic subunit
PRAMEF11 PRAME family member 11
RAD51B RAD51 paralog B
REST RE1-silencing transcription factor
RHOBTB3 Rho-related BTB domain containing 3
RPL7 ribosomal protein L7
RPS2 ribosomal protein S2
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SCAI suppressor of cancer cell invasion
SERGEF secretion regulating guanine nucleotide exchange factor
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNW1 SNW domain containing 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SREBF1 sterol regulatory element binding transcription factor 1
SSH3 slingshot protein phosphatase 3
SSX3 synovial sarcoma, X breakpoint 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STS steroid sulfatase (microsomal), isozyme S
STX7 syntaxin 7
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
SYN2 synapsin II
SYNJ2 synaptojanin 2
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TMEM231 transmembrane protein 231
TOP3A topoisomerase (DNA) III alpha
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USF2 upstream transcription factor 2, c-fos interacting
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
WDR62 WD repeat domain 62
WNT6 wingless-type MMTV integration site family, member 6
YY1 YY1 transcription factor
ZBTB25 zinc finger and BTB domain containing 25
ZNF155 zinc finger protein 155
ZNF335 zinc finger protein 335

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AKTIP AKT interacting protein
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARID5A AT rich interactive domain 5A (MRF1-like)
ASB7 ankyrin repeat and SOCS box containing 7
ASCC2 activating signal cointegrator 1 complex subunit 2
ASPN asporin
BBS10 Bardet-Biedl syndrome 10
BIN2 bridging integrator 2
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC88C coiled-coil domain containing 88C
CDADC1 cytidine and dCMP deaminase domain containing 1
CDR2L cerebellar degeneration-related protein 2-like
CEP97 centrosomal protein 97kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHML choroideremia-like (Rab escort protein 2)
CLSPN claspin
DYSF dysferlin
EDC3 enhancer of mRNA decapping 3
ELP6 elongator acetyltransferase complex subunit 6
ERCC8 excision repair cross-complementation group 8
ETAA1 Ewing tumor-associated antigen 1
FAM114A1 family with sequence similarity 114, member A1
FAM160B2 family with sequence similarity 160, member B2
FAM53B family with sequence similarity 53, member B
FAM63A family with sequence similarity 63, member A
FANCC Fanconi anemia, complementation group C
FBXL7 F-box and leucine-rich repeat protein 7
FGGY FGGY carbohydrate kinase domain containing
FGL2 fibrinogen-like 2
FKBP5 FK506 binding protein 5
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMPPA GDP-mannose pyrophosphorylase A
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR27 G protein-coupled receptor 27
HDAC5 histone deacetylase 5
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BF histone cluster 1, H2bf
HP1BP3 heterochromatin protein 1, binding protein 3
IFT81 intraflagellar transport 81
IL4R interleukin 4 receptor
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0355 KIAA0355
KIF1B kinesin family member 1B
KLHL12 kelch-like family member 12
KLHL28 kelch-like family member 28
LIG4 ligase IV, DNA, ATP-dependent
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LIMD2 LIM domain containing 2
LTB lymphotoxin beta (TNF superfamily, member 3)
MAST3 microtubule associated serine/threonine kinase 3
MBTD1 mbt domain containing 1
MBTPS1 membrane-bound transcription factor peptidase, site 1
MED15 mediator complex subunit 15
MIR22HG MIR22 host gene
MITF microphthalmia-associated transcription factor
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NT5C 5', 3'-nucleotidase, cytosolic
OCEL1 occludin/ELL domain containing 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSBPL2 oxysterol binding protein-like 2
P3H1 prolyl 3-hydroxylase 1
PARPBP PARP1 binding protein
PCSK7 proprotein convertase subtilisin/kexin type 7
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PMM1 phosphomannomutase 1
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRAF2 PRA1 domain family, member 2
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PTPRA protein tyrosine phosphatase, receptor type, A
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RGS19 regulator of G-protein signaling 19
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RNF122 ring finger protein 122
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RWDD2A RWD domain containing 2A
SARS2 seryl-tRNA synthetase 2, mitochondrial
SETD6 SET domain containing 6
SETD8 SET domain containing (lysine methyltransferase) 8
SPAG7 sperm associated antigen 7
SPATA2L spermatogenesis associated 2-like
SREK1IP1 SREK1-interacting protein 1
STBD1 starch binding domain 1
SURF2 surfeit 2
TBX19 T-box 19
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEC tec protein tyrosine kinase
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM68 tripartite motif containing 68
USB1 U6 snRNA biogenesis 1
VANGL1 VANGL planar cell polarity protein 1
ZBED8 zinc finger, BED-type containing 8
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF37BP zinc finger protein 37B, pseudogene
ZNF506 zinc finger protein 506
ZNF510 zinc finger protein 510
ZNF536 zinc finger protein 536
ZNF669 zinc finger protein 669
ZNF747 zinc finger protein 747
ZNF816 zinc finger protein 816