| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the estradiol-1182 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| AXIN1 | axin 1 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CAPN5 | calpain 5 |
| CD58 | CD58 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CLEC4A | C-type lectin domain family 4, member A |
| CRYL1 | crystallin, lambda 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 |
| CTSS | cathepsin S |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DSPP | dentin sialophosphoprotein |
| DUSP7 | dual specificity phosphatase 7 |
| DVL2 | dishevelled segment polarity protein 2 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| FAM53C | family with sequence similarity 53, member C |
| FCHO1 | FCH domain only 1 |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| FH | fumarate hydratase |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IDS | iduronate 2-sulfatase |
| INHBC | inhibin, beta C |
| INO80B | INO80 complex subunit B |
| IRX5 | iroquois homeobox 5 |
| JAG1 | jagged 1 |
| JRK | Jrk homolog (mouse) |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KLF6 | Kruppel-like factor 6 |
| KLHDC10 | kelch domain containing 10 |
| KLHL20 | kelch-like family member 20 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| METTL7A | methyltransferase like 7A |
| MIIP | migration and invasion inhibitory protein |
| MSRB2 | methionine sulfoxide reductase B2 |
| MYBBP1A | MYB binding protein (P160) 1a |
| NAG18 | NAG18 mRNA |
| NOP16 | NOP16 nucleolar protein |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDCD2 | programmed cell death 2 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PHTF2 | putative homeodomain transcription factor 2 |
| PKP4 | plakophilin 4 |
| PLK3 | polo-like kinase 3 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRAMEF11 | PRAME family member 11 |
| RAD51B | RAD51 paralog B |
| REST | RE1-silencing transcription factor |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RPL7 | ribosomal protein L7 |
| RPS2 | ribosomal protein S2 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
| SCAI | suppressor of cancer cell invasion |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SNW1 | SNW domain containing 1 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| SSH3 | slingshot protein phosphatase 3 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STS | steroid sulfatase (microsomal), isozyme S |
| STX7 | syntaxin 7 |
| SULT2A1 | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 |
| SYN2 | synapsin II |
| SYNJ2 | synaptojanin 2 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| TMEM231 | transmembrane protein 231 |
| TOP3A | topoisomerase (DNA) III alpha |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| WDR62 | WD repeat domain 62 |
| WNT6 | wingless-type MMTV integration site family, member 6 |
| YY1 | YY1 transcription factor |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZNF155 | zinc finger protein 155 |
| ZNF335 | zinc finger protein 335 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AKTIP | AKT interacting protein |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 |
| ASPN | asporin |
| BBS10 | Bardet-Biedl syndrome 10 |
| BIN2 | bridging integrator 2 |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| CCDC88C | coiled-coil domain containing 88C |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CEP97 | centrosomal protein 97kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLSPN | claspin |
| DYSF | dysferlin |
| EDC3 | enhancer of mRNA decapping 3 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERCC8 | excision repair cross-complementation group 8 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM114A1 | family with sequence similarity 114, member A1 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FAM53B | family with sequence similarity 53, member B |
| FAM63A | family with sequence similarity 63, member A |
| FANCC | Fanconi anemia, complementation group C |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FGL2 | fibrinogen-like 2 |
| FKBP5 | FK506 binding protein 5 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GMPPA | GDP-mannose pyrophosphorylase A |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPR27 | G protein-coupled receptor 27 |
| HDAC5 | histone deacetylase 5 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BF | histone cluster 1, H2bf |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFT81 | intraflagellar transport 81 |
| IL4R | interleukin 4 receptor |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KIAA0355 | KIAA0355 |
| KIF1B | kinesin family member 1B |
| KLHL12 | kelch-like family member 12 |
| KLHL28 | kelch-like family member 28 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LILRB4 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 |
| LIMD2 | LIM domain containing 2 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBTD1 | mbt domain containing 1 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 |
| MED15 | mediator complex subunit 15 |
| MIR22HG | MIR22 host gene |
| MITF | microphthalmia-associated transcription factor |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| OCEL1 | occludin/ELL domain containing 1 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OSBPL2 | oxysterol binding protein-like 2 |
| P3H1 | prolyl 3-hydroxylase 1 |
| PARPBP | PARP1 binding protein |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| PMM1 | phosphomannomutase 1 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRAF2 | PRA1 domain family, member 2 |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| PTPRA | protein tyrosine phosphatase, receptor type, A |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RGS19 | regulator of G-protein signaling 19 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RNF122 | ring finger protein 122 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RWDD2A | RWD domain containing 2A |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SETD6 | SET domain containing 6 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SPAG7 | sperm associated antigen 7 |
| SPATA2L | spermatogenesis associated 2-like |
| SREK1IP1 | SREK1-interacting protein 1 |
| STBD1 | starch binding domain 1 |
| SURF2 | surfeit 2 |
| TBX19 | T-box 19 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TEC | tec protein tyrosine kinase |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRIM68 | tripartite motif containing 68 |
| USB1 | U6 snRNA biogenesis 1 |
| VANGL1 | VANGL planar cell polarity protein 1 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF506 | zinc finger protein 506 |
| ZNF510 | zinc finger protein 510 |
| ZNF536 | zinc finger protein 536 |
| ZNF669 | zinc finger protein 669 |
| ZNF747 | zinc finger protein 747 |
| ZNF816 | zinc finger protein 816 |