estradiol-1208 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the estradiol-1208 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANXA10 annexin A10
AQR aquarius intron-binding spliceosomal factor
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ATAD5 ATPase family, AAA domain containing 5
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B9D1 B9 protein domain 1
BBC3 BCL2 binding component 3
BMP5 bone morphogenetic protein 5
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CACTIN cactin, spliceosome C complex subunit
CALD1 caldesmon 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CES2 carboxylesterase 2
CNN1 calponin 1, basic, smooth muscle
CORT cortistatin
CPB2 carboxypeptidase B2 (plasma)
CSF1R colony stimulating factor 1 receptor
DAGLA diacylglycerol lipase, alpha
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DHODH dihydroorotate dehydrogenase (quinone)
DHRS12 dehydrogenase/reductase (SDR family) member 12
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
FAM174B family with sequence similarity 174, member B
FGFR2 fibroblast growth factor receptor 2
FN1 fibronectin 1
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GGT1 gamma-glutamyltransferase 1
GPR1 G protein-coupled receptor 1
GRIK5 glutamate receptor, ionotropic, kainate 5
GSTCD glutathione S-transferase, C-terminal domain containing
HAUS5 HAUS augmin-like complex, subunit 5
HIST1H2BJ histone cluster 1, H2bj
HOXB2 homeobox B2
IL6ST interleukin 6 signal transducer
INO80B INO80 complex subunit B
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0754 KIAA0754
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT6B keratin 6B, type II
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC100287590 uncharacterized LOC100287590
LRRC1 leucine rich repeat containing 1
LRRK1 leucine-rich repeat kinase 1
MADD MAP-kinase activating death domain
MAPK11 mitogen-activated protein kinase 11
MEGF9 multiple EGF-like-domains 9
MID1 midline 1
NBEAL2 neurobeachin-like 2
NCAPH2 non-SMC condensin II complex, subunit H2
NCDN neurochondrin
NMT1 N-myristoyltransferase 1
NOX1 NADPH oxidase 1
NRGN neurogranin (protein kinase C substrate, RC3)
OPCML opioid binding protein/cell adhesion molecule-like
PDCD6 programmed cell death 6
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDLIM7 PDZ and LIM domain 7 (enigma)
PHTF2 putative homeodomain transcription factor 2
PKP3 plakophilin 3
PLA2G1B phospholipase A2, group IB (pancreas)
PLD3 phospholipase D family, member 3
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POLH polymerase (DNA directed), eta
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRB1 proline-rich protein BstNI subfamily 1
PTGES prostaglandin E synthase
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RAB31 RAB31, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RHOBTB2 Rho-related BTB domain containing 2
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC63 SEC63 homolog (S. cerevisiae)
SIRT4 sirtuin 4
SIX1 SIX homeobox 1
SLC17A2 solute carrier family 17, member 2
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SMG5 SMG5 nonsense mediated mRNA decay factor
SREBF2 sterol regulatory element binding transcription factor 2
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
SYNGR1 synaptogyrin 1
SYT5 synaptotagmin V
TJAP1 tight junction associated protein 1 (peripheral)
TJP3 tight junction protein 3
TLR2 toll-like receptor 2
TMEM209 transmembrane protein 209
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TTC9 tetratricopeptide repeat domain 9
VNN2 vanin 2
WDR25 WD repeat domain 25
ZNF214 zinc finger protein 214
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACBD4 acyl-CoA binding domain containing 4
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADGRG2 adhesion G protein-coupled receptor G2
ANXA2P3 annexin A2 pseudogene 3
APH1B APH1B gamma secretase subunit
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARSJ arylsulfatase family, member J
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BCHE butyrylcholinesterase
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTC betacellulin
C14ORF169 chromosome 14 open reading frame 169
C1QTNF1 C1q and tumor necrosis factor related protein 1
C3ORF18 chromosome 3 open reading frame 18
CA11 carbonic anhydrase XI
CASZ1 castor zinc finger 1
CCL20 chemokine (C-C motif) ligand 20
CDC37L1 cell division cycle 37-like 1
CDR2L cerebellar degeneration-related protein 2-like
CEP83 centrosomal protein 83kDa
CHML choroideremia-like (Rab escort protein 2)
CLCN5 chloride channel, voltage-sensitive 5
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DBR1 debranching RNA lariats 1
DDIT4 DNA-damage-inducible transcript 4
DNAAF2 dynein, axonemal, assembly factor 2
DPH2 DPH2 homolog (S. cerevisiae)
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EYA4 EYA transcriptional coactivator and phosphatase 4
F3 coagulation factor III (thromboplastin, tissue factor)
FAM188A family with sequence similarity 188, member A
FBXL7 F-box and leucine-rich repeat protein 7
FSD1 fibronectin type III and SPRY domain containing 1
GMEB1 glucocorticoid modulatory element binding protein 1
GPR19 G protein-coupled receptor 19
GPRIN2 G protein regulated inducer of neurite outgrowth 2
H1F0 H1 histone family, member 0
HCG4 HLA complex group 4 (non-protein coding)
HIRA histone cell cycle regulator
HMG20A high mobility group 20A
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL32 interleukin 32
IREB2 iron-responsive element binding protein 2
IRF1 interferon regulatory factor 1
KIFC1 kinesin family member C1
KRT4 keratin 4, type II
MAGEA6 melanoma antigen family A6
MANEA mannosidase, endo-alpha
MATN3 matrilin 3
MCMBP minichromosome maintenance complex binding protein
MCRS1 microspherule protein 1
MMP9 matrix metallopeptidase 9
MOB3B MOB kinase activator 3B
MOXD1 monooxygenase, DBH-like 1
MRPL28 mitochondrial ribosomal protein L28
MTG1 mitochondrial ribosome-associated GTPase 1
MTMR11 myotubularin related protein 11
MTMR12 myotubularin related protein 12
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OLFML2A olfactomedin-like 2A
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRPH peripherin
RPIA ribose 5-phosphate isomerase A
SCN9A sodium channel, voltage gated, type IX alpha subunit
SECISBP2 SECIS binding protein 2
SIDT1 SID1 transmembrane family, member 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
STK16 serine/threonine kinase 16
STX1A syntaxin 1A (brain)
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TBC1D19 TBC1 domain family, member 19
TEAD3 TEA domain family member 3
TEX40 testis expressed 40
THBS3 thrombospondin 3
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPCN1 two pore segment channel 1
TPST2 tyrosylprotein sulfotransferase 2
USP6 ubiquitin specific peptidase 6
USP8 ubiquitin specific peptidase 8
VASH2 vasohibin 2
ZNF10 zinc finger protein 10
ZNF189 zinc finger protein 189
ZNF254 zinc finger protein 254
ZNF304 zinc finger protein 304
ZNF34 zinc finger protein 34
ZNF408 zinc finger protein 408
ZNF415 zinc finger protein 415
ZNF552 zinc finger protein 552
ZNF623 zinc finger protein 623