| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the estradiol-121 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATG12 | autophagy related 12 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BBC3 | BCL2 binding component 3 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CCDC71 | coiled-coil domain containing 71 |
| CDK12 | cyclin-dependent kinase 12 |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CEP68 | centrosomal protein 68kDa |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CXXC1 | CXXC finger protein 1 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DMTN | dematin actin binding protein |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DUS2 | dihydrouridine synthase 2 |
| E2F3 | E2F transcription factor 3 |
| EFCAB14 | EF-hand calcium binding domain 14 |
| EFNB3 | ephrin-B3 |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 |
| EMC1 | ER membrane protein complex subunit 1 |
| EPS8L1 | EPS8-like 1 |
| ERCC1 | excision repair cross-complementation group 1 |
| FANCA | Fanconi anemia, complementation group A |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| FKBP2 | FK506 binding protein 2, 13kDa |
| GALK2 | galactokinase 2 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GPR107 | G protein-coupled receptor 107 |
| GPX2 | glutathione peroxidase 2 |
| GSK3A | glycogen synthase kinase 3 alpha |
| H2AFX | H2A histone family, member X |
| HIST1H3G | histone cluster 1, H3g |
| HLA-G | major histocompatibility complex, class I, G |
| HOXB1 | homeobox B1 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| JOSD1 | Josephin domain containing 1 |
| KHK | ketohexokinase (fructokinase) |
| LDLR | low density lipoprotein receptor |
| LEMD3 | LEM domain containing 3 |
| MAP4 | microtubule-associated protein 4 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MT1HL1 | metallothionein 1H-like 1 |
| MTFR1 | mitochondrial fission regulator 1 |
| MYL10 | myosin, light chain 10, regulatory |
| MYO9B | myosin IXB |
| NFYA | nuclear transcription factor Y, alpha |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NTAN1 | N-terminal asparagine amidase |
| ODF2 | outer dense fiber of sperm tails 2 |
| OGFR | opioid growth factor receptor |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PEX10 | peroxisomal biogenesis factor 10 |
| PGM3 | phosphoglucomutase 3 |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
| PLSCR3 | phospholipid scramblase 3 |
| PNISR | PNN-interacting serine/arginine-rich protein |
| PPAN | peter pan homolog (Drosophila) |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PRRC2A | proline-rich coiled-coil 2A |
| PYGB | phosphorylase, glycogen; brain |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RANBP10 | RAN binding protein 10 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| RGS12 | regulator of G-protein signaling 12 |
| RGS3 | regulator of G-protein signaling 3 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 |
| SLC41A3 | solute carrier family 41, member 3 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| STX12 | syntaxin 12 |
| SYF2 | SYF2 pre-mRNA-splicing factor |
| TBRG4 | transforming growth factor beta regulator 4 |
| TMEM127 | transmembrane protein 127 |
| TMEM161A | transmembrane protein 161A |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TTC13 | tetratricopeptide repeat domain 13 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 |
| UFSP2 | UFM1-specific peptidase 2 |
| VEZF1 | vascular endothelial zinc finger 1 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WRAP73 | WD repeat containing, antisense to TP73 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF14 | zinc finger protein 14 |
| ZNF35 | zinc finger protein 35 |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| ADIRF | adipogenesis regulatory factor |
| AEN | apoptosis enhancing nuclease |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARMC7 | armadillo repeat containing 7 |
| ATG14 | autophagy related 14 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CEP192 | centrosomal protein 192kDa |
| CHEK2 | checkpoint kinase 2 |
| CHGB | chromogranin B |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CNTNAP1 | contactin associated protein 1 |
| CRYL1 | crystallin, lambda 1 |
| DENND6B | DENN/MADD domain containing 6B |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| EPX | eosinophil peroxidase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FGF6 | fibroblast growth factor 6 |
| FKBP6 | FK506 binding protein 6, 36kDa |
| GDF3 | growth differentiation factor 3 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GNRH2 | gonadotropin-releasing hormone 2 |
| GOLM1 | golgi membrane protein 1 |
| GPATCH3 | G patch domain containing 3 |
| GPR21 | G protein-coupled receptor 21 |
| GRB7 | growth factor receptor-bound protein 7 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRM6 | glutamate receptor, metabotropic 6 |
| GSTA4 | glutathione S-transferase alpha 4 |
| GUCA1B | guanylate cyclase activator 1B (retina) |
| HOXA5 | homeobox A5 |
| HOXB2 | homeobox B2 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IL13 | interleukin 13 |
| IMPA1 | inositol(myo)-1(or 4)-monophosphatase 1 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIF15 | kinesin family member 15 |
| KIF5A | kinesin family member 5A |
| KLHL12 | kelch-like family member 12 |
| LEFTY1 | left-right determination factor 1 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LMBR1L | limb development membrane protein 1-like |
| LMTK1 | lemur tail kinase 1 |
| MIR22HG | MIR22 host gene |
| MNT | MAX network transcriptional repressor |
| NBEAL2 | neurobeachin-like 2 |
| NCSTN | nicastrin |
| NDE1 | nudE neurodevelopment protein 1 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| OSGEP | O-sialoglycoprotein endopeptidase |
| OVOL1 | ovo-like zinc finger 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| P3H1 | prolyl 3-hydroxylase 1 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PARG | poly (ADP-ribose) glycohydrolase |
| PGP | phosphoglycolate phosphatase |
| PLCD1 | phospholipase C, delta 1 |
| POU2F1 | POU class 2 homeobox 1 |
| PPOX | protoporphyrinogen oxidase |
| PRLH | prolactin releasing hormone |
| PRMT3 | protein arginine methyltransferase 3 |
| PRPH | peripherin |
| PRR4 | proline rich 4 (lacrimal) |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PSAT1 | phosphoserine aminotransferase 1 |
| RAD54L | RAD54-like (S. cerevisiae) |
| RAMP3 | receptor (G protein-coupled) activity modifying protein 3 |
| RANBP17 | RAN binding protein 17 |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SPEF1 | sperm flagellar 1 |
| SQRDL | sulfide quinone reductase-like (yeast) |
| ST5 | suppression of tumorigenicity 5 |
| STAC | SH3 and cysteine rich domain |
| STAT4 | signal transducer and activator of transcription 4 |
| STX1A | syntaxin 1A (brain) |
| TAS2R1 | taste receptor, type 2, member 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TIPRL | TOR signaling pathway regulator |
| TMPRSS6 | transmembrane protease, serine 6 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TSPYL2 | TSPY-like 2 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| ZNF267 | zinc finger protein 267 |