estradiol-1241 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the estradiol-1241 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADPRH ADP-ribosylarginine hydrolase
AKAP13 A kinase (PRKA) anchor protein 13
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ARF6 ADP-ribosylation factor 6
ATP5SL ATP5S-like
BBC3 BCL2 binding component 3
BCAM basal cell adhesion molecule (Lutheran blood group)
C2ORF27A chromosome 2 open reading frame 27A
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CALD1 caldesmon 1
CD40 CD40 molecule, TNF receptor superfamily member 5
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
COBL cordon-bleu WH2 repeat protein
CPZ carboxypeptidase Z
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
ESRRA estrogen-related receptor alpha
ETV6 ets variant 6
FAM174B family with sequence similarity 174, member B
FBXW11 F-box and WD repeat domain containing 11
FGF23 fibroblast growth factor 23
FGFR1 fibroblast growth factor receptor 1
GAS7 growth arrest-specific 7
GLP1R glucagon-like peptide 1 receptor
GRIP2 glutamate receptor interacting protein 2
HAUS5 HAUS augmin-like complex, subunit 5
HIST1H2AJ histone cluster 1, H2aj
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
ICOSLG inducible T-cell co-stimulator ligand
IFT27 intraflagellar transport 27
IGHM immunoglobulin heavy constant mu
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
INF2 inverted formin, FH2 and WH2 domain containing
INO80B INO80 complex subunit B
INPP5J inositol polyphosphate-5-phosphatase J
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNIP1 Kv channel interacting protein 1
KRIT1 KRIT1, ankyrin repeat containing
LRRK1 leucine-rich repeat kinase 1
LYZ lysozyme
LZTR1 leucine-zipper-like transcription regulator 1
MLYCD malonyl-CoA decarboxylase
MTCP1 mature T-cell proliferation 1
NMT1 N-myristoyltransferase 1
NOS1 nitric oxide synthase 1 (neuronal)
OSMR oncostatin M receptor
PDIA2 protein disulfide isomerase family A, member 2
PDLIM3 PDZ and LIM domain 3
PHF3 PHD finger protein 3
PLA2G10 phospholipase A2, group X
PLD3 phospholipase D family, member 3
POLG polymerase (DNA directed), gamma
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRF1 perforin 1 (pore forming protein)
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PRRC2B proline-rich coiled-coil 2B
PSD4 pleckstrin and Sec7 domain containing 4
RAB26 RAB26, member RAS oncogene family
RAB28 RAB28, member RAS oncogene family
RAI2 retinoic acid induced 2
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RDH16 retinol dehydrogenase 16 (all-trans)
RGS14 regulator of G-protein signaling 14
RPP25 ribonuclease P/MRP 25kDa subunit
RPS28 ribosomal protein S28
RYR2 ryanodine receptor 2 (cardiac)
SBNO2 strawberry notch homolog 2 (Drosophila)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SIRT4 sirtuin 4
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SMC4 structural maintenance of chromosomes 4
SOX21 SRY (sex determining region Y)-box 21
SPTBN2 spectrin, beta, non-erythrocytic 2
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STBD1 starch binding domain 1
STS steroid sulfatase (microsomal), isozyme S
STXBP6 syntaxin binding protein 6 (amisyn)
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
SZT2 seizure threshold 2 homolog (mouse)
TBC1D17 TBC1 domain family, member 17
TGFB2 transforming growth factor, beta 2
TJP3 tight junction protein 3
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM206 transmembrane protein 206
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TRD T cell receptor delta locus
TRIM25 tripartite motif containing 25
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USF2 upstream transcription factor 2, c-fos interacting
WFDC2 WAP four-disulfide core domain 2
WIPI2 WD repeat domain, phosphoinositide interacting 2
ZFP64 ZFP64 zinc finger protein
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF214 zinc finger protein 214
ZNF557 zinc finger protein 557

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACAD10 acyl-CoA dehydrogenase family, member 10
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADGRG2 adhesion G protein-coupled receptor G2
AGMAT agmatine ureohydrolase (agmatinase)
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AHDC1 AT hook, DNA binding motif, containing 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
AXIN1 axin 1
BAHD1 bromo adjacent homology domain containing 1
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BTBD2 BTB (POZ) domain containing 2
C11ORF30 chromosome 11 open reading frame 30
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDR2L cerebellar degeneration-related protein 2-like
CFAP44 cilia and flagella associated protein 44
CHKB choline kinase beta
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CHST10 carbohydrate sulfotransferase 10
CS citrate synthase
DBF4B DBF4 zinc finger B
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DMTN dematin actin binding protein
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
ENO2 enolase 2 (gamma, neuronal)
ERCC4 excision repair cross-complementation group 4
ESM1 endothelial cell-specific molecule 1
FAM110B family with sequence similarity 110, member B
FAM155A family with sequence similarity 155, member A
FAM169A family with sequence similarity 169, member A
FPGS folylpolyglutamate synthase
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GLCE glucuronic acid epimerase
GPR39 G protein-coupled receptor 39
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HOXC10 homeobox C10
HOXC13 homeobox C13
HYAL3 hyaluronoglucosaminidase 3
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IFT54 intraflagellar transport 54
IGFLR1 IGF-like family receptor 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0513 KIAA0513
KIAA0895 KIAA0895
KRT33A keratin 33A, type I
KRT6B keratin 6B, type II
LYPLA2P1 lysophospholipase II pseudogene 1
MCTP2 multiple C2 domains, transmembrane 2
MFSD11 major facilitator superfamily domain containing 11
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
NECAP2 NECAP endocytosis associated 2
NME5 NME/NM23 family member 5
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NOD1 nucleotide-binding oligomerization domain containing 1
NT5DC3 5'-nucleotidase domain containing 3
NXPE3 neurexophilin and PC-esterase domain family, member 3
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRR14L proline rich 14-like
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTK6 protein tyrosine kinase 6
PTK7 protein tyrosine kinase 7 (inactive)
PYCRL pyrroline-5-carboxylate reductase-like
RAB5B RAB5B, member RAS oncogene family
RNF122 ring finger protein 122
RNF31 ring finger protein 31
RPH3AL rabphilin 3A-like (without C2 domains)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SCHIP1 schwannomin interacting protein 1
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SNPH syntaphilin
SYNGR3 synaptogyrin 3
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM2 transmembrane protein 2
TOM1 target of myb1 (chicken)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBG2 tubulin, gamma 2
TXNL4B thioredoxin-like 4B
WBP2 WW domain binding protein 2
ZNF254 zinc finger protein 254
ZNF408 zinc finger protein 408
ZNF468 zinc finger protein 468
ZNF668 zinc finger protein 668
ZNF711 zinc finger protein 711
ZNF84 zinc finger protein 84