| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the estradiol-1241 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ADPRH | ADP-ribosylarginine hydrolase |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ARF6 | ADP-ribosylation factor 6 |
| ATP5SL | ATP5S-like |
| BBC3 | BCL2 binding component 3 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CALD1 | caldesmon 1 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| COBL | cordon-bleu WH2 repeat protein |
| CPZ | carboxypeptidase Z |
| CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
| ESRRA | estrogen-related receptor alpha |
| ETV6 | ets variant 6 |
| FAM174B | family with sequence similarity 174, member B |
| FBXW11 | F-box and WD repeat domain containing 11 |
| FGF23 | fibroblast growth factor 23 |
| FGFR1 | fibroblast growth factor receptor 1 |
| GAS7 | growth arrest-specific 7 |
| GLP1R | glucagon-like peptide 1 receptor |
| GRIP2 | glutamate receptor interacting protein 2 |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFT27 | intraflagellar transport 27 |
| IGHM | immunoglobulin heavy constant mu |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| INO80B | INO80 complex subunit B |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNIP1 | Kv channel interacting protein 1 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LRRK1 | leucine-rich repeat kinase 1 |
| LYZ | lysozyme |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MLYCD | malonyl-CoA decarboxylase |
| MTCP1 | mature T-cell proliferation 1 |
| NMT1 | N-myristoyltransferase 1 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| OSMR | oncostatin M receptor |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| PDLIM3 | PDZ and LIM domain 3 |
| PHF3 | PHD finger protein 3 |
| PLA2G10 | phospholipase A2, group X |
| PLD3 | phospholipase D family, member 3 |
| POLG | polymerase (DNA directed), gamma |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PRF1 | perforin 1 (pore forming protein) |
| PROC | protein C (inactivator of coagulation factors Va and VIIIa) |
| PRRC2B | proline-rich coiled-coil 2B |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| RAB26 | RAB26, member RAS oncogene family |
| RAB28 | RAB28, member RAS oncogene family |
| RAI2 | retinoic acid induced 2 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RDH16 | retinol dehydrogenase 16 (all-trans) |
| RGS14 | regulator of G-protein signaling 14 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RPS28 | ribosomal protein S28 |
| RYR2 | ryanodine receptor 2 (cardiac) |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SIRT4 | sirtuin 4 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMC4 | structural maintenance of chromosomes 4 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| STBD1 | starch binding domain 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| STXBP6 | syntaxin binding protein 6 (amisyn) |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TBC1D17 | TBC1 domain family, member 17 |
| TGFB2 | transforming growth factor, beta 2 |
| TJP3 | tight junction protein 3 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TMEM206 | transmembrane protein 206 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TRD | T cell receptor delta locus |
| TRIM25 | tripartite motif containing 25 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USF2 | upstream transcription factor 2, c-fos interacting |
| WFDC2 | WAP four-disulfide core domain 2 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| ZFP64 | ZFP64 zinc finger protein |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF214 | zinc finger protein 214 |
| ZNF557 | zinc finger protein 557 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| AXIN1 | axin 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CFAP44 | cilia and flagella associated protein 44 |
| CHKB | choline kinase beta |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CHST10 | carbohydrate sulfotransferase 10 |
| CS | citrate synthase |
| DBF4B | DBF4 zinc finger B |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DMTN | dematin actin binding protein |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFNA3 | ephrin-A3 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERCC4 | excision repair cross-complementation group 4 |
| ESM1 | endothelial cell-specific molecule 1 |
| FAM110B | family with sequence similarity 110, member B |
| FAM155A | family with sequence similarity 155, member A |
| FAM169A | family with sequence similarity 169, member A |
| FPGS | folylpolyglutamate synthase |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GLCE | glucuronic acid epimerase |
| GPR39 | G protein-coupled receptor 39 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HOXC10 | homeobox C10 |
| HOXC13 | homeobox C13 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IFT54 | intraflagellar transport 54 |
| IGFLR1 | IGF-like family receptor 1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIAA0513 | KIAA0513 |
| KIAA0895 | KIAA0895 |
| KRT33A | keratin 33A, type I |
| KRT6B | keratin 6B, type II |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| NECAP2 | NECAP endocytosis associated 2 |
| NME5 | NME/NM23 family member 5 |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRR14L | proline rich 14-like |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PTK6 | protein tyrosine kinase 6 |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB5B | RAB5B, member RAS oncogene family |
| RNF122 | ring finger protein 122 |
| RNF31 | ring finger protein 31 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SCHIP1 | schwannomin interacting protein 1 |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SNPH | syntaphilin |
| SYNGR3 | synaptogyrin 3 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMEM2 | transmembrane protein 2 |
| TOM1 | target of myb1 (chicken) |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TUBG2 | tubulin, gamma 2 |
| TXNL4B | thioredoxin-like 4B |
| WBP2 | WW domain binding protein 2 |
| ZNF254 | zinc finger protein 254 |
| ZNF408 | zinc finger protein 408 |
| ZNF468 | zinc finger protein 468 |
| ZNF668 | zinc finger protein 668 |
| ZNF711 | zinc finger protein 711 |
| ZNF84 | zinc finger protein 84 |