estradiol-1633 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the estradiol-1633 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTL8 actin-like 8
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
AMPH amphiphysin
ANKRD6 ankyrin repeat domain 6
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APLP1 amyloid beta (A4) precursor-like protein 1
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BAHCC1 BAH domain and coiled-coil containing 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BGN biglycan
CA12 carbonic anhydrase XII
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC85C coiled-coil domain containing 85C
CCDC88C coiled-coil domain containing 88C
CD82 CD82 molecule
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CLCN2 chloride channel, voltage-sensitive 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CYHR1 cysteine/histidine-rich 1
CYTH1 cytohesin 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGAT1 diacylglycerol O-acyltransferase 1
DGKE diacylglycerol kinase, epsilon 64kDa
DNAH17 dynein, axonemal, heavy chain 17
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EGR3 early growth response 3
ETV7 ets variant 7
FAM49B family with sequence similarity 49, member B
FAXDC2 fatty acid hydroxylase domain containing 2
GIF gastric intrinsic factor (vitamin B synthesis)
GPR107 G protein-coupled receptor 107
GRK5 G protein-coupled receptor kinase 5
HIST1H1D histone cluster 1, H1d
HLA-C major histocompatibility complex, class I, C
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
HOMER3 homer scaffolding protein 3
HOXC4 homeobox C4
HSPA1L heat shock 70kDa protein 1-like
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
LAMB3 laminin, beta 3
LHX1 LIM homeobox 1
LPCAT3 lysophosphatidylcholine acyltransferase 3
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MARK4 MAP/microtubule affinity-regulating kinase 4
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MPO myeloperoxidase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEK9 NIMA-related kinase 9
NPY1R neuropeptide Y receptor Y1
NR4A1 nuclear receptor subfamily 4, group A, member 1
PDZK1 PDZ domain containing 1
PEX5 peroxisomal biogenesis factor 5
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLXNB3 plexin B3
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP1R37 protein phosphatase 1, regulatory subunit 37
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PTPRS protein tyrosine phosphatase, receptor type, S
PTRF polymerase I and transcript release factor
RAD52 RAD52 homolog (S. cerevisiae)
RAD54B RAD54 homolog B (S. cerevisiae)
RGS10 regulator of G-protein signaling 10
RGS12 regulator of G-protein signaling 12
RNF170 ring finger protein 170
RPGRIP1L RPGRIP1-like
RPS4Y1 ribosomal protein S4, Y-linked 1
SAFB2 scaffold attachment factor B2
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SGK1 serum/glucocorticoid regulated kinase 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMAD4 SMAD family member 4
SORBS3 sorbin and SH3 domain containing 3
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPPL2B signal peptide peptidase like 2B
SSBP3 single stranded DNA binding protein 3
SSTR4 somatostatin receptor 4
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAOK2 TAO kinase 2
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBX10 T-box 10
TCP11L1 t-complex 11, testis-specific-like 1
TFF2 trefoil factor 2
TMEM212 transmembrane protein 212
TRIM25 tripartite motif containing 25
TTLL5 tubulin tyrosine ligase-like family member 5
VAC14 Vac14 homolog (S. cerevisiae)
VGF VGF nerve growth factor inducible
WDTC1 WD and tetratricopeptide repeats 1
WSCD1 WSC domain containing 1
YIPF4 Yip1 domain family, member 4
ZC3H7B zinc finger CCCH-type containing 7B
ZNF611 zinc finger protein 611

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADAM15 ADAM metallopeptidase domain 15
ADORA2B adenosine A2b receptor
ANXA1 annexin A1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGAP12 Rho GTPase activating protein 12
ARL15 ADP-ribosylation factor-like 15
ASB9 ankyrin repeat and SOCS box containing 9
ATP11B ATPase, class VI, type 11B
BBS7 Bardet-Biedl syndrome 7
BTBD2 BTB (POZ) domain containing 2
C11ORF68 chromosome 11 open reading frame 68
C11ORF80 chromosome 11 open reading frame 80
C17ORF70 chromosome 17 open reading frame 70
C19ORF40 chromosome 19 open reading frame 40
C1ORF56 chromosome 1 open reading frame 56
C4ORF29 chromosome 4 open reading frame 29
CCP110 centriolar coiled coil protein 110kDa
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLASP1 cytoplasmic linker associated protein 1
CLASRP CLK4-associating serine/arginine rich protein
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DSE dermatan sulfate epimerase
EAF2 ELL associated factor 2
EFNA1 ephrin-A1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FADS3 fatty acid desaturase 3
FCHSD2 FCH and double SH3 domains 2
FLJ22184
FMO4 flavin containing monooxygenase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FPGS folylpolyglutamate synthase
FSD1 fibronectin type III and SPRY domain containing 1
FZD4 frizzled class receptor 4
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GCDH glutaryl-CoA dehydrogenase
GHR growth hormone receptor
GLTSCR1 glioma tumor suppressor candidate region gene 1
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
GTPBP2 GTP binding protein 2
GUSBP3 glucuronidase, beta pseudogene 3
HOXC11 homeobox C11
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IRF6 interferon regulatory factor 6
KAT2A K(lysine) acetyltransferase 2A
KCTD20 potassium channel tetramerization domain containing 20
KIZ kizuna centrosomal protein
KLC2 kinesin light chain 2
LIMA1 LIM domain and actin binding 1
MANBA mannosidase, beta A, lysosomal
MICALL2 MICAL-like 2
MINPP1 multiple inositol-polyphosphate phosphatase 1
MNX1 motor neuron and pancreas homeobox 1
NABP2 nucleic acid binding protein 2
NHEJ1 nonhomologous end-joining factor 1
NPM3 nucleophosmin/nucleoplasmin 3
NUP62CL nucleoporin 62kDa C-terminal like
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PAN2 PAN2 poly(A) specific ribonuclease subunit
PCTP phosphatidylcholine transfer protein
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDZRN3 PDZ domain containing ring finger 3
PER3 period circadian clock 3
PGPEP1 pyroglutamyl-peptidase I
PHACTR4 phosphatase and actin regulator 4
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRR15L proline rich 15-like
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIPK4 receptor-interacting serine-threonine kinase 4
RLF rearranged L-myc fusion
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCAMP4 secretory carrier membrane protein 4
SHARPIN SHANK-associated RH domain interactor
SHPK sedoheptulokinase
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNX16 sorting nexin 16
SQRDL sulfide quinone reductase-like (yeast)
SYNGR3 synaptogyrin 3
TCTN1 tectonic family member 1
TPRA1 transmembrane protein, adipocyte asscociated 1
TPST1 tyrosylprotein sulfotransferase 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPYL2 TSPY-like 2
WDR19 WD repeat domain 19
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZC3H3 zinc finger CCCH-type containing 3
ZNF654 zinc finger protein 654
ZNF85 zinc finger protein 85