| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the estradiol-2653 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| AAK1 | AP2 associated kinase 1 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ABHD2 | abhydrolase domain containing 2 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| AREG | amphiregulin |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BRCA2 | breast cancer 2, early onset |
| C3 | complement component 3 |
| CA4 | carbonic anhydrase IV |
| CD70 | CD70 molecule |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNMBP | dynamin binding protein |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DUSP2 | dual specificity phosphatase 2 |
| EGR3 | early growth response 3 |
| EIF5B | eukaryotic translation initiation factor 5B |
| ELF2 | E74-like factor 2 (ets domain transcription factor) |
| FAM76A | family with sequence similarity 76, member A |
| FBXO21 | F-box protein 21 |
| FOXG1 | forkhead box G1 |
| FXR2 | fragile X mental retardation, autosomal homolog 2 |
| GLP1R | glucagon-like peptide 1 receptor |
| HOXC8 | homeobox C8 |
| HR | hair growth associated |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MED28 | mediator complex subunit 28 |
| MID2 | midline 2 |
| MITF | microphthalmia-associated transcription factor |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MTM1 | myotubularin 1 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NCALD | neurocalcin delta |
| NCS1 | neuronal calcium sensor 1 |
| NOL12 | nucleolar protein 12 |
| NOP16 | NOP16 nucleolar protein |
| NR2C1 | nuclear receptor subfamily 2, group C, member 1 |
| PDHA2 | pyruvate dehydrogenase (lipoamide) alpha 2 |
| PER1 | period circadian clock 1 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POU2F2 | POU class 2 homeobox 2 |
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRKCI | protein kinase C, iota |
| PSPH | phosphoserine phosphatase |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RHOQ | ras homolog family member Q |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RPL10 | ribosomal protein L10 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SAV1 | salvador family WW domain containing protein 1 |
| SEC24A | SEC24 family member A |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SOCS5 | suppressor of cytokine signaling 5 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPON2 | spondin 2, extracellular matrix protein |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| SUN1 | Sad1 and UNC84 domain containing 1 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TBC1D2B | TBC1 domain family, member 2B |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TGM2 | transglutaminase 2 |
| TMEM120B | transmembrane protein 120B |
| TRIM29 | tripartite motif containing 29 |
| UTRN | utrophin |
| VEGFA | vascular endothelial growth factor A |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF696 | zinc finger protein 696 |
| ZNF747 | zinc finger protein 747 |
| ZNF778 | zinc finger protein 778 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| BMP4 | bone morphogenetic protein 4 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C5AR2 | complement component 5a receptor 2 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CBX7 | chromobox homolog 7 |
| CCDC25 | coiled-coil domain containing 25 |
| CCNO | cyclin O |
| CDK3 | cyclin-dependent kinase 3 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN9 | claudin 9 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTSV | cathepsin V |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DEAF1 | DEAF1 transcription factor |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNM1 | dynamin 1 |
| EFNA1 | ephrin-A1 |
| EMID1 | EMI domain containing 1 |
| EPHA4 | EPH receptor A4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EXO5 | exonuclease 5 |
| FCHSD2 | FCH and double SH3 domains 2 |
| FILIP1L | filamin A interacting protein 1-like |
| FLCN | folliculin |
| FPGS | folylpolyglutamate synthase |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GAMT | guanidinoacetate N-methyltransferase |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPR157 | G protein-coupled receptor 157 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| HYI | hydroxypyruvate isomerase (putative) |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| JMJD4 | jumonji domain containing 4 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LRRC61 | leucine rich repeat containing 61 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MCOLN3 | mucolipin 3 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MYO1F | myosin IF |
| NDE1 | nudE neurodevelopment protein 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NNAT | neuronatin |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| PCDHB3 | protocadherin beta 3 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POLL | polymerase (DNA directed), lambda |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RIN2 | Ras and Rab interactor 2 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RSG1 | REM2 and RAB-like small GTPase 1 |
| SAA4 | serum amyloid A4, constitutive |
| SECTM1 | secreted and transmembrane 1 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SSTR5 | somatostatin receptor 5 |
| TEP1 | telomerase-associated protein 1 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM121 | transmembrane protein 121 |
| TMEM212 | transmembrane protein 212 |
| TONSL | tonsoku-like, DNA repair protein |
| TRIM21 | tripartite motif containing 21 |
| TUBA3C | tubulin, alpha 3c |
| UNC119 | unc-119 homolog (C. elegans) |
| USP20 | ubiquitin specific peptidase 20 |
| VASH1 | vasohibin 1 |
| VPS9D1 | VPS9 domain containing 1 |
| XAB2 | XPA binding protein 2 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF446 | zinc finger protein 446 |
