| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the estradiol-2668 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ARMC6 | armadillo repeat containing 6 |
| ATXN2L | ataxin 2-like |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BCAN | brevican |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CD300C | CD300c molecule |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CREM | cAMP responsive element modulator |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DCN | decorin |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DUX1 | double homeobox 1 |
| DXO | decapping exoribonuclease |
| EPHB3 | EPH receptor B3 |
| F2RL2 | coagulation factor II (thrombin) receptor-like 2 |
| FAAH | fatty acid amide hydrolase |
| FAM46C | family with sequence similarity 46, member C |
| FHL1 | four and a half LIM domains 1 |
| FOXO4 | forkhead box O4 |
| GK3P | glycerol kinase 3 pseudogene |
| GP5 | glycoprotein V (platelet) |
| GPR182 | G protein-coupled receptor 182 |
| GPR45 | G protein-coupled receptor 45 |
| GPR50 | G protein-coupled receptor 50 |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HOXB5 | homeobox B5 |
| ITGA8 | integrin, alpha 8 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA0513 | KIAA0513 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LIMK2 | LIM domain kinase 2 |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MED14 | mediator complex subunit 14 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MMP3 | matrix metallopeptidase 3 |
| MNMIP1 | manchette microtubule inner protein 1 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
| NID1 | nidogen 1 |
| NPEPL1 | aminopeptidase-like 1 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PER3 | period circadian clock 3 |
| PERP | PERP, TP53 apoptosis effector |
| PHF1 | PHD finger protein 1 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PVR | poliovirus receptor |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RDX | radixin |
| RGS13 | regulator of G-protein signaling 13 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC35D2 | solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SOSTDC1 | sclerostin domain containing 1 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYNM | synemin, intermediate filament protein |
| TNIK | TRAF2 and NCK interacting kinase |
| TRAPPC9 | trafficking protein particle complex 9 |
| TRIM25 | tripartite motif containing 25 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TYMP | thymidine phosphorylase |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 |
| VSIG10 | V-set and immunoglobulin domain containing 10 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF337 | zinc finger protein 337 |
| ZNF34 | zinc finger protein 34 |
| Symbol | Name |
|---|---|
| ADAM2 | ADAM metallopeptidase domain 2 |
| ADGRE3 | adhesion G protein-coupled receptor E3 |
| AEN | apoptosis enhancing nuclease |
| AMT | aminomethyltransferase |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| BSPRY | B-box and SPRY domain containing |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| C8A | complement component 8, alpha polypeptide |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CCDC92 | coiled-coil domain containing 92 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD70 | CD70 molecule |
| CDK20 | cyclin-dependent kinase 20 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CDON | cell adhesion associated, oncogene regulated |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| CNN1 | calponin 1, basic, smooth muscle |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DOK3 | docking protein 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| GPR3 | G protein-coupled receptor 3 |
| GSTZ1 | glutathione S-transferase zeta 1 |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BF | histone cluster 1, H2bf |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H3G | histone cluster 1, H3g |
| HOXC8 | homeobox C8 |
| HPR | haptoglobin-related protein |
| IFNA14 | interferon, alpha 14 |
| IFT140 | intraflagellar transport 140 |
| IFT46 | intraflagellar transport 46 |
| IL2 | interleukin 2 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KCNA6 | potassium channel, voltage gated shaker related subfamily A, member 6 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIAA0754 | KIAA0754 |
| KIAA1456 | KIAA1456 |
| KIF20A | kinesin family member 20A |
| KRT81 | keratin 81, type II |
| LIMD2 | LIM domain containing 2 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MCPH1 | microcephalin 1 |
| METTL16 | methyltransferase like 16 |
| MXD3 | MAX dimerization protein 3 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NEUROD4 | neuronal differentiation 4 |
| NKX3-2 | NK3 homeobox 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NXF2 | nuclear RNA export factor 2 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PIPOX | pipecolic acid oxidase |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PRSS53 | protease, serine, 53 |
| RAPSN | receptor-associated protein of the synapse |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SIX3 | SIX homeobox 3 |
| SLC16A6 | solute carrier family 16, member 6 |
| SPON2 | spondin 2, extracellular matrix protein |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SYNPO2L | synaptopodin 2-like |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCTA | T-cell leukemia translocation altered |
| TMEM180 | transmembrane protein 180 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNS2 | tensin 2 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| UBQLN4 | ubiquilin 4 |
| UNC13A | unc-13 homolog A (C. elegans) |
| VEGFC | vascular endothelial growth factor C |
| WDR25 | WD repeat domain 25 |
| ZNF76 | zinc finger protein 76 |
