| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the estradiol-2701 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTN2 | actinin, alpha 2 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AKR1C4 | aldo-keto reductase family 1, member C4 |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ARHGAP35 | Rho GTPase activating protein 35 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BMP8B | bone morphogenetic protein 8b |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CD84 | CD84 molecule |
| CDY1 | chromodomain protein, Y-linked, 1 |
| CEP295 | centrosomal protein 295kDa |
| COL1A2 | collagen, type I, alpha 2 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CXXC4 | CXXC finger protein 4 |
| CYHR1 | cysteine/histidine-rich 1 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DIAPH2 | diaphanous-related formin 2 |
| DMC1 | DNA meiotic recombinase 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DZIP3 | DAZ interacting zinc finger protein 3 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EPHB2 | EPH receptor B2 |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| FAM63B | family with sequence similarity 63, member B |
| FCAR | Fc fragment of IgA receptor |
| FCMR | Fc fragment of IgM receptor |
| FHL1 | four and a half LIM domains 1 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GK3P | glycerol kinase 3 pseudogene |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HIST1H3H | histone cluster 1, H3h |
| HPSE2 | heparanase 2 (inactive) |
| ICAM1 | intercellular adhesion molecule 1 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIF1C | kinesin family member 1C |
| KIF24 | kinesin family member 24 |
| KLHL23 | kelch-like family member 23 |
| MDFIC | MyoD family inhibitor domain containing |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MMRN2 | multimerin 2 |
| MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MVP | major vault protein |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NOL10 | nucleolar protein 10 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAPPA2 | pappalysin 2 |
| PDLIM3 | PDZ and LIM domain 3 |
| PENK | proenkephalin |
| PER3 | period circadian clock 3 |
| PHTF2 | putative homeodomain transcription factor 2 |
| PIP | prolactin-induced protein |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PROL1 | proline rich, lacrimal 1 |
| RANBP1 | RAN binding protein 1 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 |
| RASAL2 | RAS protein activator like 2 |
| RDX | radixin |
| RPGRIP1L | RPGRIP1-like |
| RPH3A | rabphilin 3A |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC38A7 | solute carrier family 38, member 7 |
| SPAG1 | sperm associated antigen 1 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| TAGLN3 | transgelin 3 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TECPR2 | tectonin beta-propeller repeat containing 2 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TRIM45 | tripartite motif containing 45 |
| TTC12 | tetratricopeptide repeat domain 12 |
| TTC30A | tetratricopeptide repeat domain 30A |
| UBE3A | ubiquitin protein ligase E3A |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| ZBTB1 | zinc finger and BTB domain containing 1 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZNF174 | zinc finger protein 174 |
| ZNF500 | zinc finger protein 500 |
| ZNF675 | zinc finger protein 675 |
| Symbol | Name |
|---|---|
| ADGB | androglobin |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BDKRB1 | bradykinin receptor B1 |
| BPY2 | basic charge, Y-linked, 2 |
| BSPRY | B-box and SPRY domain containing |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| C8A | complement component 8, alpha polypeptide |
| CA11 | carbonic anhydrase XI |
| CABP2 | calcium binding protein 2 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CCDC92 | coiled-coil domain containing 92 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CEMP1 | cementum protein 1 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| CPNE7 | copine VII |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 |
| DNM3 | dynamin 3 |
| DPEP2 | dipeptidase 2 |
| DSPP | dentin sialophosphoprotein |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| FGF23 | fibroblast growth factor 23 |
| FGF6 | fibroblast growth factor 6 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| G0S2 | G0/G1 switch 2 |
| GABARAPL3 | GABA(A) receptors associated protein like 3, pseudogene |
| GALK1 | galactokinase 1 |
| GPR68 | G protein-coupled receptor 68 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) |
| HEYL | hes-related family bHLH transcription factor with YRPW motif-like |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H3G | histone cluster 1, H3g |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HOXB9 | homeobox B9 |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| IBSP | integrin-binding sialoprotein |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| JAM3 | junctional adhesion molecule 3 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIAA1456 | KIAA1456 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC100287590 | uncharacterized LOC100287590 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PADI1 | peptidyl arginine deiminase, type I |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PCDHGA11 | protocadherin gamma subfamily A, 11 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PGP | phosphoglycolate phosphatase |
| PLA2G15 | phospholipase A2, group XV |
| PRDM12 | PR domain containing 12 |
| PRF1 | perforin 1 (pore forming protein) |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| RAB13 | RAB13, member RAS oncogene family |
| RAPSN | receptor-associated protein of the synapse |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SFRP5 | secreted frizzled-related protein 5 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 |
| SMR3B | submaxillary gland androgen regulated protein 3B |
| SPATA2L | spermatogenesis associated 2-like |
| SPIDR | scaffolding protein involved in DNA repair |
| STEAP4 | STEAP family member 4 |
| SYNPO2L | synaptopodin 2-like |
| TCTN1 | tectonic family member 1 |
| TMEM212 | transmembrane protein 212 |
| TPM3 | tropomyosin 3 |
| VASH1 | vasohibin 1 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VEGFC | vascular endothelial growth factor C |
| VNN1 | vanin 1 |
| ZNF10 | zinc finger protein 10 |
| ZNF480 | zinc finger protein 480 |
| ZNF85 | zinc finger protein 85 |