| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the estradiol-365 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ARHGAP19 | Rho GTPase activating protein 19 |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa |
| ASCL3 | achaete-scute family bHLH transcription factor 3 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATP13A2 | ATPase type 13A2 |
| B3GAT3 | beta-1,3-glucuronyltransferase 3 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| BRCA1 | breast cancer 1, early onset |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CADM3 | cell adhesion molecule 3 |
| CCDC94 | coiled-coil domain containing 94 |
| CDC25C | cell division cycle 25C |
| CDH8 | cadherin 8, type 2 |
| CDK6 | cyclin-dependent kinase 6 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| COBL | cordon-bleu WH2 repeat protein |
| COL1A2 | collagen, type I, alpha 2 |
| CRYAB | crystallin, alpha B |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific |
| EVPL | envoplakin |
| EXOC7 | exocyst complex component 7 |
| FAM153A | family with sequence similarity 153, member A |
| FAM76A | family with sequence similarity 76, member A |
| FASTK | Fas-activated serine/threonine kinase |
| FBLN5 | fibulin 5 |
| FOLR3 | folate receptor 3 (gamma) |
| FOSL2 | FOS-like antigen 2 |
| FZD10 | frizzled class receptor 10 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GNRH2 | gonadotropin-releasing hormone 2 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HLA-G | major histocompatibility complex, class I, G |
| HMGA1 | high mobility group AT-hook 1 |
| HMX1 | H6 family homeobox 1 |
| HNF1A | HNF1 homeobox A |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HSPA4 | heat shock 70kDa protein 4 |
| IKZF2 | IKAROS family zinc finger 2 (Helios) |
| IL19 | interleukin 19 |
| KIAA0040 | KIAA0040 |
| KLF2 | Kruppel-like factor 2 |
| LUZP1 | leucine zipper protein 1 |
| MPPE1 | metallophosphoesterase 1 |
| MPV17 | MpV17 mitochondrial inner membrane protein |
| MT1HL1 | metallothionein 1H-like 1 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow |
| MYO1F | myosin IF |
| NF1 | neurofibromin 1 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NRF1 | nuclear respiratory factor 1 |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
| ORC4 | origin recognition complex, subunit 4 |
| PARVA | parvin, alpha |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PQLC2 | PQ loop repeat containing 2 |
| PRG3 | proteoglycan 3 |
| PTEN | phosphatase and tensin homolog |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RAB3D | RAB3D, member RAS oncogene family |
| RAB8B | RAB8B, member RAS oncogene family |
| RARA | retinoic acid receptor, alpha |
| RFTN1 | raftlin, lipid raft linker 1 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SIRPA | signal-regulatory protein alpha |
| SLAMF8 | SLAM family member 8 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| SSTR2 | somatostatin receptor 2 |
| STX12 | syntaxin 12 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TG | thyroglobulin |
| TGFA | transforming growth factor, alpha |
| THBS4 | thrombospondin 4 |
| TP63 | tumor protein p63 |
| TRAC | T cell receptor alpha constant |
| TRAF2 | TNF receptor-associated factor 2 |
| TSPAN32 | tetraspanin 32 |
| TXNRD2 | thioredoxin reductase 2 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| YLPM1 | YLP motif containing 1 |
| ZFHX2 | zinc finger homeobox 2 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ACVRL1 | activin A receptor type II-like 1 |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| BNC1 | basonuclin 1 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CARS2 | cysteinyl-tRNA synthetase 2, mitochondrial (putative) |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CBX8 | chromobox homolog 8 |
| CCDC87 | coiled-coil domain containing 87 |
| CD2 | CD2 molecule |
| CEP41 | centrosomal protein 41kDa |
| CIDEB | cell death-inducing DFFA-like effector b |
| CORO1A | coronin, actin binding protein, 1A |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DCLRE1A | DNA cross-link repair 1A |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| ECE2 | endothelin converting enzyme 2 |
| EDA2R | ectodysplasin A2 receptor |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FCGR1B | Fc fragment of IgG, high affinity Ib, receptor (CD64) |
| FGGY | FGGY carbohydrate kinase domain containing |
| FRMD1 | FERM domain containing 1 |
| FSTL4 | follistatin-like 4 |
| GABRQ | gamma-aminobutyric acid (GABA) A receptor, theta |
| GFAP | glial fibrillary acidic protein |
| GLI1 | GLI family zinc finger 1 |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 |
| GP9 | glycoprotein IX (platelet) |
| GSPT2 | G1 to S phase transition 2 |
| H2AFY2 | H2A histone family, member Y2 |
| HINFP | histone H4 transcription factor |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IL36A | interleukin 36, alpha |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KLHDC8A | kelch domain containing 8A |
| KLHL11 | kelch-like family member 11 |
| KLHL25 | kelch-like family member 25 |
| KLHL3 | kelch-like family member 3 |
| LIN28A | lin-28 homolog A (C. elegans) |
| LINC00474 | long intergenic non-protein coding RNA 474 |
| LOC81691 | exonuclease NEF-sp |
| LUZP2 | leucine zipper protein 2 |
| MAGEC3 | melanoma antigen family C3 |
| MAOB | monoamine oxidase B |
| MC3R | melanocortin 3 receptor |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MT4 | metallothionein 4 |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast |
| MYOZ3 | myozenin 3 |
| OPRK1 | opioid receptor, kappa 1 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PCDH11X | protocadherin 11 X-linked |
| PDZD7 | PDZ domain containing 7 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PGC | progastricsin (pepsinogen C) |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| POMT1 | protein-O-mannosyltransferase 1 |
| POPDC2 | popeye domain containing 2 |
| PRKCZ | protein kinase C, zeta |
| PRO2964 | uncharacterized protein PRO2964 |
| RANBP17 | RAN binding protein 17 |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SLC10A2 | solute carrier family 10 (sodium/bile acid cotransporter), member 2 |
| SLC39A2 | solute carrier family 39 (zinc transporter), member 2 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STAB2 | stabilin 2 |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| STAT5A | signal transducer and activator of transcription 5A |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THBS2 | thrombospondin 2 |
| TMEM50A | transmembrane protein 50A |
| TMPRSS5 | transmembrane protease, serine 5 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TSLIG2 | tRNA splicing ligase complex subunit 2 |
| TWIST1 | twist family bHLH transcription factor 1 |
| UBQLN4 | ubiquilin 4 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VWA1 | von Willebrand factor A domain containing 1 |
| WNT2 | wingless-type MMTV integration site family member 2 |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZIC4 | Zic family member 4 |
| ZNF394 | zinc finger protein 394 |
| ZNRF4 | zinc and ring finger 4 |
