| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the estradiol-373 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTN4 | actinin, alpha 4 |
| AK1 | adenylate kinase 1 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| ANGPTL2 | angiopoietin-like 2 |
| ARMC7 | armadillo repeat containing 7 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATG13 | autophagy related 13 |
| ATR | ATR serine/threonine kinase |
| ATXN2L | ataxin 2-like |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BICD2 | bicaudal D homolog 2 (Drosophila) |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CA12 | carbonic anhydrase XII |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CBX8 | chromobox homolog 8 |
| CD53 | CD53 molecule |
| CDC37L1 | cell division cycle 37-like 1 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 |
| CHD1L | chromodomain helicase DNA binding protein 1-like |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
| DUS2 | dihydrouridine synthase 2 |
| DXO | decapping exoribonuclease |
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| GAS7 | growth arrest-specific 7 |
| GTPBP2 | GTP binding protein 2 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| IFNA17 | interferon, alpha 17 |
| ITGA6 | integrin, alpha 6 |
| JAK2 | Janus kinase 2 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIR3DS1 | killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 |
| KLHL28 | kelch-like family member 28 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MAGEA5 | melanoma antigen family A5 |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MEX3C | mex-3 RNA binding family member C |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MPPED2 | metallophosphoesterase domain containing 2 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MVP | major vault protein |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MZF1 | myeloid zinc finger 1 |
| NKX3-1 | NK3 homeobox 1 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| OTUD3 | OTU deubiquitinase 3 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PALLD | palladin, cytoskeletal associated protein |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PDZK1 | PDZ domain containing 1 |
| PGRMC2 | progesterone receptor membrane component 2 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLCD1 | phospholipase C, delta 1 |
| PLCL2 | phospholipase C-like 2 |
| PRDM11 | PR domain containing 11 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTGES | prostaglandin E synthase |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAB27A | RAB27A, member RAS oncogene family |
| RANBP10 | RAN binding protein 10 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RET | ret proto-oncogene |
| RFPL2 | ret finger protein-like 2 |
| RGS3 | regulator of G-protein signaling 3 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RUNX1 | runt-related transcription factor 1 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SEC23A | Sec23 homolog A (S. cerevisiae) |
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SH2B2 | SH2B adaptor protein 2 |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 |
| SIRT5 | sirtuin 5 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| TGM2 | transglutaminase 2 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TSPO2 | translocator protein 2 |
| ZMYM4 | zinc finger, MYM-type 4 |
| ZNF528 | zinc finger protein 528 |
| ZNF638 | zinc finger protein 638 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain |
| AES | amino-terminal enhancer of split |
| AIM2 | absent in melanoma 2 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| ARG1 | arginase 1 |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| BAGE | B melanoma antigen |
| BHMT | betaine--homocysteine S-methyltransferase |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BMP10 | bone morphogenetic protein 10 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCL16 | chemokine (C-C motif) ligand 16 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) |
| CHKB | choline kinase beta |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DAGLA | diacylglycerol lipase, alpha |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DLK2 | delta-like 2 homolog (Drosophila) |
| EPHA4 | EPH receptor A4 |
| FAM106A | family with sequence similarity 106, member A |
| FIGF | c-fos induced growth factor (vascular endothelial growth factor D) |
| FOLR2 | folate receptor 2 (fetal) |
| FSTL1 | follistatin-like 1 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GALR3 | galanin receptor 3 |
| GMIP | GEM interacting protein |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPR173 | G protein-coupled receptor 173 |
| HDAC11 | histone deacetylase 11 |
| HMP19 | HMP19 protein |
| HOXC13 | homeobox C13 |
| HPGDS | hematopoietic prostaglandin D synthase |
| HSD17B3 | hydroxysteroid (17-beta) dehydrogenase 3 |
| HTR3B | 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFT140 | intraflagellar transport 140 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| ILK | integrin-linked kinase |
| KCNAB3 | potassium channel, voltage gated subfamily A regulatory beta subunit 3 |
| KCNJ10 | potassium channel, inwardly rectifying subfamily J, member 10 |
| KCNJ9 | potassium channel, inwardly rectifying subfamily J, member 9 |
| KIAA0513 | KIAA0513 |
| KLHL25 | kelch-like family member 25 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 |
| LECT1 | leukocyte cell derived chemotaxin 1 |
| LHX6 | LIM homeobox 6 |
| LINC00574 | long intergenic non-protein coding RNA 574 |
| LMTK1 | lemur tail kinase 1 |
| LRRC61 | leucine rich repeat containing 61 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MST1 | macrophage stimulating 1 |
| MT1HL1 | metallothionein 1H-like 1 |
| MXRA5 | matrix-remodelling associated 5 |
| MYBPC3 | myosin binding protein C, cardiac |
| NLK | nemo-like kinase |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
| NPTX1 | neuronal pentraxin I |
| PADI1 | peptidyl arginine deiminase, type I |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PCTP | phosphatidylcholine transfer protein |
| PDCD1 | programmed cell death 1 |
| PRDM16 | PR domain containing 16 |
| PRRG3 | proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RAB1B | RAB1B, member RAS oncogene family |
| RNF141 | ring finger protein 141 |
| SCGN | secretagogin, EF-hand calcium binding protein |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNX6 | sorting nexin 6 |
| SPON2 | spondin 2, extracellular matrix protein |
| SPRR3 | small proline-rich protein 3 |
| STAB2 | stabilin 2 |
| STAG3 | stromal antigen 3 |
| STX1A | syntaxin 1A (brain) |
| SYF2 | SYF2 pre-mRNA-splicing factor |
| TCTN1 | tectonic family member 1 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TPK1 | thiamin pyrophosphokinase 1 |
| TSNAX | translin-associated factor X |
| TTC1 | tetratricopeptide repeat domain 1 |
| TTC26 | tetratricopeptide repeat domain 26 |
| TTC4 | tetratricopeptide repeat domain 4 |
| TTN | titin |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| ZNF358 | zinc finger protein 358 |
| ZNF701 | zinc finger protein 701 |
| ZNRF4 | zinc and ring finger 4 |