| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the estradiol-387 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCF2 | ATP-binding cassette, sub-family F (GCN20), member 2 |
| ACOT9 | acyl-CoA thioesterase 9 |
| ADAM20 | ADAM metallopeptidase domain 20 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AP4S1 | adaptor-related protein complex 4, sigma 1 subunit |
| ARMC7 | armadillo repeat containing 7 |
| ATF6 | activating transcription factor 6 |
| BAIAP2 | BAI1-associated protein 2 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| C8B | complement component 8, beta polypeptide |
| CA12 | carbonic anhydrase XII |
| CAV3 | caveolin 3 |
| CCDC85B | coiled-coil domain containing 85B |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHRNG | cholinergic receptor, nicotinic, gamma (muscle) |
| CIITA | class II, major histocompatibility complex, transactivator |
| CLIC4 | chloride intracellular channel 4 |
| COQ3 | coenzyme Q3 methyltransferase |
| CRYM | crystallin, mu |
| CSN2 | casein beta |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DIXDC1 | DIX domain containing 1 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DOCK10 | dedicator of cytokinesis 10 |
| DPF2 | D4, zinc and double PHD fingers family 2 |
| DYSF | dysferlin |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| ERCC8 | excision repair cross-complementation group 8 |
| FEM1C | fem-1 homolog c (C. elegans) |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GLRA2 | glycine receptor, alpha 2 |
| GPKOW | G patch domain and KOW motifs |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BI | histone cluster 1, H2bi |
| HK2 | hexokinase 2 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HMOX2 | heme oxygenase 2 |
| ICAM1 | intercellular adhesion molecule 1 |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| KAT6B | K(lysine) acetyltransferase 6B |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLHL25 | kelch-like family member 25 |
| KRT6A | keratin 6A, type II |
| L1CAM | L1 cell adhesion molecule |
| LMF2 | lipase maturation factor 2 |
| LOXL2 | lysyl oxidase-like 2 |
| LRMP | lymphoid-restricted membrane protein |
| LUC7L | LUC7-like (S. cerevisiae) |
| LUZP1 | leucine zipper protein 1 |
| MAGEC1 | melanoma antigen family C1 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MED8 | mediator complex subunit 8 |
| MGMT | O-6-methylguanine-DNA methyltransferase |
| MIPEP | mitochondrial intermediate peptidase |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NDRG3 | NDRG family member 3 |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| NR1I3 | nuclear receptor subfamily 1, group I, member 3 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| OCRL | oculocerebrorenal syndrome of Lowe |
| PADI2 | peptidyl arginine deiminase, type II |
| PDE8A | phosphodiesterase 8A |
| PIGV | phosphatidylinositol glycan anchor biosynthesis, class V |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 |
| PTCD1 | pentatricopeptide repeat domain 1 |
| RASL11B | RAS-like, family 11, member B |
| RASSF7 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SCARB2 | scavenger receptor class B, member 2 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 |
| SLC38A7 | solute carrier family 38, member 7 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| SPN | sialophorin |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| TCF3 | transcription factor 3 |
| TGFA | transforming growth factor, alpha |
| THADA | thyroid adenoma associated |
| TMEM127 | transmembrane protein 127 |
| TMEM161A | transmembrane protein 161A |
| TMF1 | TATA element modulatory factor 1 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TUBA4B | tubulin, alpha 4b |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| ZNF592 | zinc finger protein 592 |
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| AURKC | aurora kinase C |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BHMT | betaine--homocysteine S-methyltransferase |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BTN1A1 | butyrophilin, subfamily 1, member A1 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CD207 | CD207 molecule, langerin |
| CD68 | CD68 molecule |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CD82 | CD82 molecule |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 |
| CEP170B | centrosomal protein 170B |
| CHMP1A | charged multivesicular body protein 1A |
| CLEC2B | C-type lectin domain family 2, member B |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| CRYAB | crystallin, alpha B |
| CST4 | cystatin S |
| CSTB | cystatin B (stefin B) |
| CTAGE9 | CTAGE family, member 9 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DDR2 | discoidin domain receptor tyrosine kinase 2 |
| DENND6B | DENN/MADD domain containing 6B |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| EGR2 | early growth response 2 |
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa |
| EPS8L3 | EPS8-like 3 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FAM64A | family with sequence similarity 64, member A |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| FSTL4 | follistatin-like 4 |
| GAPDHS | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic |
| GDF3 | growth differentiation factor 3 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GML | glycosylphosphatidylinositol anchored molecule like |
| GP6 | glycoprotein VI (platelet) |
| GPC3 | glypican 3 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HDAC5 | histone deacetylase 5 |
| HMX1 | H6 family homeobox 1 |
| HPGDS | hematopoietic prostaglandin D synthase |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KLC2 | kinesin light chain 2 |
| KLF15 | Kruppel-like factor 15 |
| KLK8 | kallikrein-related peptidase 8 |
| LHB | luteinizing hormone beta polypeptide |
| LIPF | lipase, gastric |
| LOC145678 | uncharacterized LOC145678 |
| LYRM9 | LYR motif containing 9 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MB | myoglobin |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MGC12488 | |
| MYO9A | myosin IXA |
| NAT8 | N-acetyltransferase 8 (GCN5-related, putative) |
| NCS1 | neuronal calcium sensor 1 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NOTCH4 | notch 4 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 |
| NRSN2 | neurensin 2 |
| OR7A17 | olfactory receptor, family 7, subfamily A, member 17 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PCTP | phosphatidylcholine transfer protein |
| PF4 | platelet factor 4 |
| PLBD1 | phospholipase B domain containing 1 |
| PNPO | pyridoxamine 5'-phosphate oxidase |
| PRDM16 | PR domain containing 16 |
| PYGM | phosphorylase, glycogen, muscle |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RBP1 | retinol binding protein 1, cellular |
| RLBP1 | retinaldehyde binding protein 1 |
| RNF220 | ring finger protein 220 |
| SETMAR | SET domain and mariner transposase fusion gene |
| SHPK | sedoheptulokinase |
| SLIT2 | slit homolog 2 (Drosophila) |
| SNRNP35 | small nuclear ribonucleoprotein 35kDa (U11/U12) |
| SPAG11A | sperm associated antigen 11A |
| SPEF1 | sperm flagellar 1 |
| SST | somatostatin |
| ST5 | suppression of tumorigenicity 5 |
| SUSD4 | sushi domain containing 4 |
| TMSB15B | thymosin beta 15B |
| TNF | tumor necrosis factor |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| WNT2 | wingless-type MMTV integration site family member 2 |
| ZNF35 | zinc finger protein 35 |
| ZNF507 | zinc finger protein 507 |
