| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the estradiol-5318 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ADCY9 | adenylate cyclase 9 |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| AREG | amphiregulin |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ASPH | aspartate beta-hydroxylase |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| CASKIN2 | CASK interacting protein 2 |
| CD44 | CD44 molecule (Indian blood group) |
| CD82 | CD82 molecule |
| CHMP6 | charged multivesicular body protein 6 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CIC | capicua transcriptional repressor |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| CSPP1 | centrosome and spindle pole associated protein 1 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNMBP | dynamin binding protein |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EGR3 | early growth response 3 |
| EPHA2 | EPH receptor A2 |
| ERI3 | ERI1 exoribonuclease family member 3 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM155A | family with sequence similarity 155, member A |
| FGFR3 | fibroblast growth factor receptor 3 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLOT1 | flotillin 1 |
| FZD7 | frizzled class receptor 7 |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GPATCH3 | G patch domain containing 3 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial |
| INSIG2 | insulin induced gene 2 |
| IRS2 | insulin receptor substrate 2 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| JAK2 | Janus kinase 2 |
| JRK | Jrk homolog (mouse) |
| JUND | jun D proto-oncogene |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LMF1 | lipase maturation factor 1 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MFAP2 | microfibrillar-associated protein 2 |
| MPC1 | mitochondrial pyruvate carrier 1 |
| MTMR3 | myotubularin related protein 3 |
| MXD4 | MAX dimerization protein 4 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| PC | pyruvate carboxylase |
| PCDHB3 | protocadherin beta 3 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PODXL2 | podocalyxin-like 2 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB6A | RAB6A, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RARA | retinoic acid receptor, alpha |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RPS28 | ribosomal protein S28 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| S100A4 | S100 calcium binding protein A4 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SHOX2 | short stature homeobox 2 |
| SIK3 | SIK family kinase 3 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SREBF2 | sterol regulatory element binding transcription factor 2 |
| STAT5B | signal transducer and activator of transcription 5B |
| STK10 | serine/threonine kinase 10 |
| TAOK1 | TAO kinase 1 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TP53I11 | tumor protein p53 inducible protein 11 |
| UBQLN4 | ubiquilin 4 |
| USP2 | ubiquitin specific peptidase 2 |
| VEGFA | vascular endothelial growth factor A |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| WDR19 | WD repeat domain 19 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| ZNF318 | zinc finger protein 318 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ADCY6 | adenylate cyclase 6 |
| ADORA2B | adenosine A2b receptor |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) |
| ATG9A | autophagy related 9A |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CCDC15 | coiled-coil domain containing 15 |
| CCDC91 | coiled-coil domain containing 91 |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CORO2A | coronin, actin binding protein, 2A |
| CPTP | ceramide-1-phosphate transfer protein |
| CYB5R1 | cytochrome b5 reductase 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DENND1B | DENN/MADD domain containing 1B |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNM1 | dynamin 1 |
| DUSP22 | dual specificity phosphatase 22 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EFNA1 | ephrin-A1 |
| EFNB2 | ephrin-B2 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 |
| ESRP2 | epithelial splicing regulatory protein 2 |
| FBRS | fibrosin |
| FHOD1 | formin homology 2 domain containing 1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GATAD2A | GATA zinc finger domain containing 2A |
| GHR | growth hormone receptor |
| GMIP | GEM interacting protein |
| H2AFJ | H2A histone family, member J |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HIRA | histone cell cycle regulator |
| HIRIP3 | HIRA interacting protein 3 |
| HOXA5 | homeobox A5 |
| HOXC6 | homeobox C6 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFI6 | interferon, alpha-inducible protein 6 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa |
| IREB2 | iron-responsive element binding protein 2 |
| IRF9 | interferon regulatory factor 9 |
| JADE3 | jade family PHD finger 3 |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KIF1B | kinesin family member 1B |
| KIZ | kizuna centrosomal protein |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LIN37 | lin-37 DREAM MuvB core complex component |
| LMNB1 | lamin B1 |
| LOC100287590 | uncharacterized LOC100287590 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MLYCD | malonyl-CoA decarboxylase |
| MSX1 | msh homeobox 1 |
| MXRA7 | matrix-remodelling associated 7 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| OSGEP | O-sialoglycoprotein endopeptidase |
| PGM1 | phosphoglucomutase 1 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PPAP2C | phosphatidic acid phosphatase type 2C |
| PPL | periplakin |
| PQLC1 | PQ loop repeat containing 1 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PROS1 | protein S (alpha) |
| PYGB | phosphorylase, glycogen; brain |
| RANBP17 | RAN binding protein 17 |
| RBM41 | RNA binding motif protein 41 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF219 | ring finger protein 219 |
| SAV1 | salvador family WW domain containing protein 1 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SOAT1 | sterol O-acyltransferase 1 |
| STBD1 | starch binding domain 1 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TCEAL1 | transcription elongation factor A (SII)-like 1 |
| TESK2 | testis-specific kinase 2 |
| TMC7 | transmembrane channel-like 7 |
| TMED1 | transmembrane emp24 protein transport domain containing 1 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TTC26 | tetratricopeptide repeat domain 26 |
| USP47 | ubiquitin specific peptidase 47 |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| WWC2 | WW and C2 domain containing 2 |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| ZNF226 | zinc finger protein 226 |
| ZNF239 | zinc finger protein 239 |
| ZNF571 | zinc finger protein 571 |
