estradiol-5601 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the estradiol-5601 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AGRP agouti related neuropeptide
AHSP alpha hemoglobin stabilizing protein
AKAP1 A kinase (PRKA) anchor protein 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDOB aldolase B, fructose-bisphosphate
APOL3 apolipoprotein L, 3
ARC activity-regulated cytoskeleton-associated protein
ART1 ADP-ribosyltransferase 1
ATF6B activating transcription factor 6 beta
ATP10B ATPase, class V, type 10B
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
C6ORF10 chromosome 6 open reading frame 10
CA1 carbonic anhydrase I
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CCDC181 coiled-coil domain containing 181
CCDC64 coiled-coil domain containing 64
CCL23 chemokine (C-C motif) ligand 23
CCR9 chemokine (C-C motif) receptor 9
CD209 CD209 molecule
CD58 CD58 molecule
CD70 CD70 molecule
CDHR2 cadherin-related family member 2
CDK12 cyclin-dependent kinase 12
COL14A1 collagen, type XIV, alpha 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DFNB31 deafness, autosomal recessive 31
DGAT1 diacylglycerol O-acyltransferase 1
DOCK5 dedicator of cytokinesis 5
DOK2 docking protein 2, 56kDa
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EGR3 early growth response 3
EHD2 EH-domain containing 2
EXOSC2 exosome component 2
FLJ11292
FSCN1 fascin actin-bundling protein 1
GH1 growth hormone 1
GHRHR growth hormone releasing hormone receptor
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIPK2 homeodomain interacting protein kinase 2
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
HPSE2 heparanase 2 (inactive)
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
INSR insulin receptor
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB6 integrin, beta 6
JAK3 Janus kinase 3
KAZN kazrin, periplakin interacting protein
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KHSRP KH-type splicing regulatory protein
KLK1 kallikrein 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LINC00597 long intergenic non-protein coding RNA 597
LONRF3 LON peptidase N-terminal domain and ring finger 3
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCAM1 neural cell adhesion molecule 1
NKX2-8 NK2 homeobox 8
NOP14-AS1 NOP14 antisense RNA 1
NPAS2 neuronal PAS domain protein 2
NRF1 nuclear respiratory factor 1
OMD osteomodulin
OSBPL10 oxysterol binding protein-like 10
PCDHB12 protocadherin beta 12
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PLVAP plasmalemma vesicle associated protein
PLXNA2 plexin A2
POU2F2 POU class 2 homeobox 2
PRELP proline/arginine-rich end leucine-rich repeat protein
PSD4 pleckstrin and Sec7 domain containing 4
RAG2 recombination activating gene 2
RGS12 regulator of G-protein signaling 12
RGS14 regulator of G-protein signaling 14
RNF17 ring finger protein 17
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCN5A sodium channel, voltage gated, type V alpha subunit
SIX3 SIX homeobox 3
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SOGA1 suppressor of glucose, autophagy associated 1
SPATA1 spermatogenesis associated 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPRR2B small proline-rich protein 2B
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRSF7 serine/arginine-rich splicing factor 7
SYBU syntabulin (syntaxin-interacting)
TAL1 T-cell acute lymphocytic leukemia 1
TIMP3 TIMP metallopeptidase inhibitor 3
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TSHR thyroid stimulating hormone receptor
TYRP1 tyrosinase-related protein 1
UNC5B unc-5 homolog B (C. elegans)
YY2 YY2 transcription factor

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ACSF2 acyl-CoA synthetase family member 2
ADAP2 ArfGAP with dual PH domains 2
ADM adrenomedullin
ADTRP androgen-dependent TFPI-regulating protein
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAHCC1 BAH domain and coiled-coil containing 1
C19ORF73 chromosome 19 open reading frame 73
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C5AR2 complement component 5a receptor 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CIR1 corepressor interacting with RBPJ, 1
COPZ2 coatomer protein complex, subunit zeta 2
CSTA cystatin A (stefin A)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DNAL4 dynein, axonemal, light chain 4
EGFL7 EGF-like-domain, multiple 7
ERCC6 excision repair cross-complementation group 6
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLJ11710 uncharacterized protein FLJ11710
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GALK1 galactokinase 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLB1L galactosidase, beta 1-like
GPATCH2L G patch domain containing 2-like
HDAC5 histone deacetylase 5
HIST1H2AL histone cluster 1, H2al
HLA-J major histocompatibility complex, class I, J (pseudogene)
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IFT54 intraflagellar transport 54
INO80D INO80 complex subunit D
INPP5J inositol polyphosphate-5-phosphatase J
IRF6 interferon regulatory factor 6
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0319L KIAA0319-like
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KREMEN2 kringle containing transmembrane protein 2
LAMP3 lysosomal-associated membrane protein 3
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC157562 uncharacterized LOC157562
LOC730101 uncharacterized LOC730101
LRRC8E leucine rich repeat containing 8 family, member E
LZTS3 leucine zipper, putative tumor suppressor family member 3
MCOLN3 mucolipin 3
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MRPL41 mitochondrial ribosomal protein L41
NCALD neurocalcin delta
NIPAL2 NIPA-like domain containing 2
NXPH4 neurexophilin 4
OSGIN1 oxidative stress induced growth inhibitor 1
PADI1 peptidyl arginine deiminase, type I
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLK3 polo-like kinase 3
PLSCR4 phospholipid scramblase 4
PLXNA3 plexin A3
POMT2 protein-O-mannosyltransferase 2
PROS1 protein S (alpha)
RHBDD3 rhomboid domain containing 3
RNF122 ring finger protein 122
RNF39 ring finger protein 39
RPL23AP32 ribosomal protein L23a pseudogene 32
RPUSD2 RNA pseudouridylate synthase domain containing 2
RRAGB Ras-related GTP binding B
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SENP7 SUMO1/sentrin specific peptidase 7
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLMO1 slowmo homolog 1 (Drosophila)
SLPI secretory leukocyte peptidase inhibitor
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
STX5 syntaxin 5
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D17 TBC1 domain family, member 17
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFBR1 transforming growth factor, beta receptor 1
TICAM1 toll-like receptor adaptor molecule 1
TMEM242 transmembrane protein 242
TMEM254 transmembrane protein 254
TNS2 tensin 2
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM25 tripartite motif containing 25
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBTD1 ubiquitin domain containing 1
UPP1 uridine phosphorylase 1
USP19 ubiquitin specific peptidase 19
WDR25 WD repeat domain 25
WDR62 WD repeat domain 62
WLS wntless Wnt ligand secretion mediator
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF137P zinc finger protein 137, pseudogene
ZNF211 zinc finger protein 211
ZNF219 zinc finger protein 219
ZNF446 zinc finger protein 446
ZNF510 zinc finger protein 510
ZNF606 zinc finger protein 606
ZNF804A zinc finger protein 804A