| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the estradiol-5905 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide |
| ATP9B | ATPase, class II, type 9B |
| CADM3 | cell adhesion molecule 3 |
| CCT8L2 | chaperonin containing TCP1, subunit 8 (theta)-like 2 |
| CD22 | CD22 molecule |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CELF2 | CUGBP, Elav-like family member 2 |
| CEP295 | centrosomal protein 295kDa |
| CFAP69 | cilia and flagella associated protein 69 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CYHR1 | cysteine/histidine-rich 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DFNB31 | deafness, autosomal recessive 31 |
| DNMT3L | DNA (cytosine-5-)-methyltransferase 3-like |
| DTNA | dystrobrevin, alpha |
| EGR3 | early growth response 3 |
| EPHB2 | EPH receptor B2 |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| ETV7 | ets variant 7 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 |
| FAM182B | family with sequence similarity 182, member B |
| FHL1 | four and a half LIM domains 1 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GNAS | GNAS complex locus |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HFE | hemochromatosis |
| HLA-C | major histocompatibility complex, class I, C |
| IL11RA | interleukin 11 receptor, alpha |
| IQCC | IQ motif containing C |
| JAK2 | Janus kinase 2 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KLF2 | Kruppel-like factor 2 |
| KRT6B | keratin 6B, type II |
| LTC4S | leukotriene C4 synthase |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MED25 | mediator complex subunit 25 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MLANA | melan-A |
| MST1 | macrophage stimulating 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PADI3 | peptidyl arginine deiminase, type III |
| PDE5A | phosphodiesterase 5A, cGMP-specific |
| PGAM2 | phosphoglycerate mutase 2 (muscle) |
| PLAT | plasminogen activator, tissue |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PML | promyelocytic leukemia |
| PODNL1 | podocan-like 1 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRSS53 | protease, serine, 53 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| RARA | retinoic acid receptor, alpha |
| REC8 | REC8 meiotic recombination protein |
| RELN | reelin |
| RNF122 | ring finger protein 122 |
| RNF17 | ring finger protein 17 |
| RORC | RAR-related orphan receptor C |
| RPS11 | ribosomal protein S11 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SENP5 | SUMO1/sentrin specific peptidase 5 |
| SFTPC | surfactant protein C |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| STK24 | serine/threonine kinase 24 |
| STX7 | syntaxin 7 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 |
| TBKBP1 | TBK1 binding protein 1 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TDRKH | tudor and KH domain containing |
| TFF2 | trefoil factor 2 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMEM259 | transmembrane protein 259 |
| TMEM59L | transmembrane protein 59-like |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TSC22D2 | TSC22 domain family, member 2 |
| TTC22 | tetratricopeptide repeat domain 22 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| VWA5A | von Willebrand factor A domain containing 5A |
| WAS | Wiskott-Aldrich syndrome |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF235 | zinc finger protein 235 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ACTA1 | actin, alpha 1, skeletal muscle |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ART1 | ADP-ribosyltransferase 1 |
| AVPR1B | arginine vasopressin receptor 1B |
| BCL2A1 | BCL2-related protein A1 |
| BCO1 | beta-carotene oxygenase 1 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CABP5 | calcium binding protein 5 |
| CACNG3 | calcium channel, voltage-dependent, gamma subunit 3 |
| CBX8 | chromobox homolog 8 |
| CCDC71 | coiled-coil domain containing 71 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CETN1 | centrin, EF-hand protein, 1 |
| CLCA1 | chloride channel accessory 1 |
| CORT | cortistatin |
| CPLX2 | complexin 2 |
| CRLF1 | cytokine receptor-like factor 1 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DUOX2 | dual oxidase 2 |
| EMP3 | epithelial membrane protein 3 |
| ERCC6 | excision repair cross-complementation group 6 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GIPR | gastric inhibitory polypeptide receptor |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR21 | G protein-coupled receptor 21 |
| GRAMD1C | GRAM domain containing 1C |
| HAO1 | hydroxyacid oxidase (glycolate oxidase) 1 |
| HOXB2 | homeobox B2 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IFNA14 | interferon, alpha 14 |
| IFNA16 | interferon, alpha 16 |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| INHA | inhibin, alpha |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KCNIP2 | Kv channel interacting protein 2 |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA0125 | KIAA0125 |
| KLHL28 | kelch-like family member 28 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LECT2 | leukocyte cell-derived chemotaxin 2 |
| LENEP | lens epithelial protein |
| MALL | mal, T-cell differentiation protein-like |
| MAPK10 | mitogen-activated protein kinase 10 |
| NANOG | Nanog homeobox |
| NKX3-2 | NK3 homeobox 2 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PALM | paralemmin |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCDH12 | protocadherin 12 |
| PLAC4 | placenta-specific 4 |
| PLTP | phospholipid transfer protein |
| POU5F1B | POU class 5 homeobox 1B |
| RAB40A | RAB40A, member RAS oncogene family |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| S1PR2 | sphingosine-1-phosphate receptor 2 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLAMF7 | SLAM family member 7 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLFN12 | schlafen family member 12 |
| SOCS7 | suppressor of cytokine signaling 7 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STON1 | stonin 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TBC1D2 | TBC1 domain family, member 2 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TDRD12 | tudor domain containing 12 |
| TEX14 | testis expressed 14 |
| TMPRSS5 | transmembrane protease, serine 5 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| UPP1 | uridine phosphorylase 1 |
| USB1 | U6 snRNA biogenesis 1 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDR62 | WD repeat domain 62 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XCR1 | chemokine (C motif) receptor 1 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF329 | zinc finger protein 329 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF423 | zinc finger protein 423 |
| ZNF76 | zinc finger protein 76 |