| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the estradiol-5910 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM10 | ADAM metallopeptidase domain 10 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| ASTN2 | astrotactin 2 |
| ATP5C1 | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 |
| ATP9A | ATPase, class II, type 9A |
| BBC3 | BCL2 binding component 3 |
| BMP2 | bone morphogenetic protein 2 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CALD1 | caldesmon 1 |
| CEP152 | centrosomal protein 152kDa |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| CHRNE | cholinergic receptor, nicotinic, epsilon (muscle) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLSTN3 | calsyntenin 3 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DOCK6 | dedicator of cytokinesis 6 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| EEA1 | early endosome antigen 1 |
| EGFR | epidermal growth factor receptor |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| FOXG1 | forkhead box G1 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GFER | growth factor, augmenter of liver regeneration |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR161 | G protein-coupled receptor 161 |
| GPR25 | G protein-coupled receptor 25 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| INADL | InaD-like (Drosophila) |
| IRF4 | interferon regulatory factor 4 |
| LRRC75B | leucine rich repeat containing 75B |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MFAP3L | microfibrillar-associated protein 3-like |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MMP25 | matrix metallopeptidase 25 |
| MST1 | macrophage stimulating 1 |
| MUC3A | mucin 3A, cell surface associated |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NDNF | neuron-derived neurotrophic factor |
| NF2 | neurofibromin 2 (merlin) |
| NKX3-2 | NK3 homeobox 2 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| NPTX1 | neuronal pentraxin I |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NRF1 | nuclear respiratory factor 1 |
| OGFR | opioid growth factor receptor |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PCDH1 | protocadherin 1 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PGM5 | phosphoglucomutase 5 |
| PI4KB | phosphatidylinositol 4-kinase, catalytic, beta |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| RAB27B | RAB27B, member RAS oncogene family |
| RAB2A | RAB2A, member RAS oncogene family |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
| RGS17 | regulator of G-protein signaling 17 |
| RHBDD3 | rhomboid domain containing 3 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF122 | ring finger protein 122 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCARB2 | scavenger receptor class B, member 2 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TM2D1 | TM2 domain containing 1 |
| TOX4 | TOX high mobility group box family member 4 |
| TRAIP | TRAF interacting protein |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
| TRIM22 | tripartite motif containing 22 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF268 | zinc finger protein 268 |
| ZNF41 | zinc finger protein 41 |
| ZNF675 | zinc finger protein 675 |
| ZNF74 | zinc finger protein 74 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| AADAC | arylacetamide deacetylase |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AEN | apoptosis enhancing nuclease |
| AIM2 | absent in melanoma 2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| APOL6 | apolipoprotein L, 6 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| AURKC | aurora kinase C |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC181 | coiled-coil domain containing 181 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CD80 | CD80 molecule |
| CEL | carboxyl ester lipase |
| CHRDL1 | chordin-like 1 |
| CLIC3 | chloride intracellular channel 3 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COBL | cordon-bleu WH2 repeat protein |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| EN2 | engrailed homeobox 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM110B | family with sequence similarity 110, member B |
| FAM131B | family with sequence similarity 131, member B |
| FAM46C | family with sequence similarity 46, member C |
| FAM63A | family with sequence similarity 63, member A |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FKBP5 | FK506 binding protein 5 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| FZD10 | frizzled class receptor 10 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GK2 | glycerol kinase 2 |
| GPR157 | G protein-coupled receptor 157 |
| GPR85 | G protein-coupled receptor 85 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3G | histone cluster 1, H3g |
| HIST1H4E | histone cluster 1, H4e |
| ICAM5 | intercellular adhesion molecule 5, telencephalin |
| IFT81 | intraflagellar transport 81 |
| KIAA1456 | KIAA1456 |
| KRT31 | keratin 31, type I |
| LIPG | lipase, endothelial |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| MANEA | mannosidase, endo-alpha |
| MAP3K7CL | MAP3K7 C-terminal like |
| MRAS | muscle RAS oncogene homolog |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| NCALD | neurocalcin delta |
| NIPAL2 | NIPA-like domain containing 2 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDZK1 | PDZ domain containing 1 |
| PIPOX | pipecolic acid oxidase |
| PRR4 | proline rich 4 (lacrimal) |
| PRSS22 | protease, serine, 22 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SCRT1 | scratch family zinc finger 1 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| STIM1 | stromal interaction molecule 1 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TFDP3 | transcription factor Dp family, member 3 |
| TFEB | transcription factor EB |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TMEM74B | transmembrane protein 74B |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TONSL | tonsoku-like, DNA repair protein |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TTC26 | tetratricopeptide repeat domain 26 |
| TTC30A | tetratricopeptide repeat domain 30A |
| VN1R1 | vomeronasal 1 receptor 1 |
| ZNF362 | zinc finger protein 362 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF573 | zinc finger protein 573 |