| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the estradiol-5955 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATN1 | atrophin 1 |
| BAIAP3 | BAI1-associated protein 3 |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BIRC7 | baculoviral IAP repeat containing 7 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CD22 | CD22 molecule |
| CD8A | CD8a molecule |
| CDC25A | cell division cycle 25A |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| COL21A1 | collagen, type XXI, alpha 1 |
| COL5A1 | collagen, type V, alpha 1 |
| COL6A3 | collagen, type VI, alpha 3 |
| CXADR | coxsackie virus and adenovirus receptor |
| DIO2 | deiodinase, iodothyronine, type II |
| DOCK6 | dedicator of cytokinesis 6 |
| DTNA | dystrobrevin, alpha |
| DUSP6 | dual specificity phosphatase 6 |
| DVL2 | dishevelled segment polarity protein 2 |
| ESR1 | estrogen receptor 1 |
| F12 | coagulation factor XII (Hageman factor) |
| FABP7 | fatty acid binding protein 7, brain |
| FMOD | fibromodulin |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| GPM6B | glycoprotein M6B |
| GPR3 | G protein-coupled receptor 3 |
| HHAT | hedgehog acyltransferase |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IRF5 | interferon regulatory factor 5 |
| ITGA6 | integrin, alpha 6 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LAT2 | linker for activation of T cells family, member 2 |
| LEFTY2 | left-right determination factor 2 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LINC00312 | long intergenic non-protein coding RNA 312 |
| LMAN1 | lectin, mannose-binding, 1 |
| LOXL3 | lysyl oxidase-like 3 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MAP1B | microtubule-associated protein 1B |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like |
| MAX | MYC associated factor X |
| MED18 | mediator complex subunit 18 |
| MLX | MLX, MAX dimerization protein |
| MORN1 | MORN repeat containing 1 |
| MVB12B | multivesicular body subunit 12B |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NF1 | neurofibromin 1 |
| NOV | nephroblastoma overexpressed |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PAPPA2 | pappalysin 2 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PCDHB13 | protocadherin beta 13 |
| PCNX | pecanex homolog (Drosophila) |
| PDE12 | phosphodiesterase 12 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POLL | polymerase (DNA directed), lambda |
| POU2F2 | POU class 2 homeobox 2 |
| PTCRA | pre T-cell antigen receptor alpha |
| QKI | QKI, KH domain containing, RNA binding |
| RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| SCARB1 | scavenger receptor class B, member 1 |
| SECTM1 | secreted and transmembrane 1 |
| SH2B1 | SH2B adaptor protein 1 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 |
| SPAG8 | sperm associated antigen 8 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STK3 | serine/threonine kinase 3 |
| STK38L | serine/threonine kinase 38 like |
| STRN | striatin, calmodulin binding protein |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TBC1D5 | TBC1 domain family, member 5 |
| TFG | TRK-fused gene |
| TMEM242 | transmembrane protein 242 |
| TRIM3 | tripartite motif containing 3 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBGCP2 | tubulin, gamma complex associated protein 2 |
| ULBP2 | UL16 binding protein 2 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF227 | zinc finger protein 227 |
| ZNF589 | zinc finger protein 589 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ALS2CL | ALS2 C-terminal like |
| AMH | anti-Mullerian hormone |
| ANXA1 | annexin A1 |
| ARMC4 | armadillo repeat containing 4 |
| ASIC2 | acid sensing (proton gated) ion channel 2 |
| ATP10D | ATPase, class V, type 10D |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CARD9 | caspase recruitment domain family, member 9 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CD53 | CD53 molecule |
| CFAP45 | cilia and flagella associated protein 45 |
| COLEC11 | collectin sub-family member 11 |
| DAPK2 | death-associated protein kinase 2 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DMTN | dematin actin binding protein |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ECEL1 | endothelin converting enzyme-like 1 |
| EPX | eosinophil peroxidase |
| F2R | coagulation factor II (thrombin) receptor |
| FAM131A | family with sequence similarity 131, member A |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| GPC3 | glypican 3 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GRM2 | glutamate receptor, metabotropic 2 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIST1H1T | histone cluster 1, H1t |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| KCNE2 | potassium channel, voltage gated subfamily E regulatory beta subunit 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA0319L | KIAA0319-like |
| KIAA0754 | KIAA0754 |
| KIAA1107 | KIAA1107 |
| KLRF1 | killer cell lectin-like receptor subfamily F, member 1 |
| LHX3 | LIM homeobox 3 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LMTK1 | lemur tail kinase 1 |
| LOC157562 | uncharacterized LOC157562 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LPAR3 | lysophosphatidic acid receptor 3 |
| MAP1S | microtubule-associated protein 1S |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MEFV | Mediterranean fever |
| MMRN2 | multimerin 2 |
| MX1 | MX dynamin-like GTPase 1 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NKX3-2 | NK3 homeobox 2 |
| NNAT | neuronatin |
| NOTCH4 | notch 4 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PALM | paralemmin |
| PGP | phosphoglycolate phosphatase |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| POU5F1B | POU class 5 homeobox 1B |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RGS2 | regulator of G-protein signaling 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RORC | RAR-related orphan receptor C |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| S100A9 | S100 calcium binding protein A9 |
| SCAMP3 | secretory carrier membrane protein 3 |
| SDC3 | syndecan 3 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SSTR5 | somatostatin receptor 5 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMPRSS6 | transmembrane protease, serine 6 |
| TRABD | TraB domain containing |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
| TRAPPC11 | trafficking protein particle complex 11 |
| VAX2 | ventral anterior homeobox 2 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| XYLT1 | xylosyltransferase I |
| ZNF286A | zinc finger protein 286A |
| ZNF510 | zinc finger protein 510 |
| ZNF747 | zinc finger protein 747 |